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The product of P2RY1 belongs to the family of G-protein coupled receptors. Additionally we are shipping P2RY1 Kits (5) and P2RY1 Proteins (5) and many more products for this protein.
Showing 10 out of 91 products:
Cat (Feline) Polyclonal P2RY1 Primary Antibody for EIA, WB - ABIN493183
Abbracchio, Burnstock: Purinoceptors: are there families of P2X and P2Y purinoceptors? in Pharmacology & therapeutics 1995
Show all 5 references for ABIN493183
Human Polyclonal P2RY1 Primary Antibody for WB - ABIN2784500
Dilip, Ishii, Imada, Wada-Kiyama, Kiyama, Miyachi, Kaneda: Distribution and development of P2Y1-purinoceptors in the mouse retina. in Journal of molecular histology 2013
Human Monoclonal P2RY1 Primary Antibody for IF, ELISA - ABIN518571
Coyle, ODonnell, Puri: Altered distribution of small-conductance calcium-activated potassium channel SK3 in Hirschsprung's disease. in Journal of pediatric surgery 2015
Human Polyclonal P2RY1 Primary Antibody for ELISA, WB - ABIN334454
Arthur, Shen, Mu, Leon, Gachet, Berndt, Andrews: Calmodulin interacts with the platelet ADP receptor P2Y1. in The Biochemical journal 2006
Human Polyclonal P2RY1 Primary Antibody for IHC, WB - ABIN1742028
Jin, Daniel, Kunapuli: Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets. in The Journal of biological chemistry 1998
In P2Y1R (-/-) mice, the expression of P2Y2 (show P2RY2 Antibodies) receptor in muscle was reduced by over 50 %, as compared to P2Y1R (+/+) mice. P2Y1 receptor regulated the neuromuscular junction gene expression.
Our current results suggest that P2Y1 modulates heat responsiveness and chemosensation in muscle afferents to play a key role in the development of pain-related behaviors during ischemia.
Provide evidence for purinergic glio-endothelial coupling during neuronal activity, highlighting the role of ATP-mediated activation of eNOS (show NOS3 Antibodies) via P2Y1 receptors in functional hyperemia.
P2Y1 couples to and activates TRPV4 (show TRPV4 Antibodies). PKC (show PKC Antibodies) inhibitors prevented P2Y1 receptor activation of TRPV4 (show TRPV4 Antibodies).
The analysis of single and double KO mice demonstrated that NTPDase2 (show ENTPD2 Antibodies) and P2Y1 receptors are not required for murine eye formation
Data indicate that knock down of purinergic P2Y1 receptors inhibited directed migration in neurospheres.
In a mouse model of Alzheimer disease, astroglial network dysfunction is mediated by P2Y1 receptor signalling in reactive astrocytes.
RhoA (show RHOA Antibodies) signaling downstream of platelet P2Y, but not P2Y, represents a clear dichotomy in platelet activation during allergic inflammation versus hemostasis.
purines activate SK currents via mainly P2Y1 receptors in PDGFRalpha(+) cells
It involves in LPS (show TLR4 Antibodies)-induced IL-6 (show IL6 Antibodies) production in Kupffer cells, leading to the liver inflammation.
Synergistic inhibition of both P2Y1 and P2Y12 (show P2RY12 Antibodies) adenosine diphosphate receptors by GLS (show GLS Antibodies)-409 immediately attenuates platelet-mediated thrombosis and effectively blocks agonist-stimulated platelet aggregation irrespective of concomitant aspirin therapy.
P2Y1 couples to and activates TRPV4 (show TRPV4 Antibodies). PKC (show PRRT2 Antibodies) inhibitors prevented P2Y1 receptor activation of TRPV4 (show TRPV4 Antibodies).
P2Y1 receptors are a potential pharmacological target leading smooth muscle relaxation to treat spasticity in colonic motor disorders.
Data indicate that ATP-evoked Hoechst 33258 uptake was dependent on activation of P2Y receptors P2Y1 and P2Y2 (show P2RY2 Antibodies).
These studies demonstrate a role for P2Y receptor activation in stimulation of ATP release.
The immunohistochemical results were reflected in the immunoblotting data P2RY1 receptors were detected at higher levels of expression in patient with cortical dysplasia with intractable epilepsy.
P2Y1 and P2Y12 (show P2RY12 Antibodies) genes were polymorphic in a Korean population; 3 intronic P2Y12 (show P2RY12 Antibodies) polymorphisms (i-139C>T, i-744T>C, i-801insA) were in complete linkage disequilibrium but not with the c.52C>T polymorphism; platelet aggregation in response to ADP associated with c.52C>T polymorphism but not with the 3 intronic polymorphisms or the P2Y1 c.1622A>T polymorphism
We think that allele G provides a protective effect in events of ventilatory stress. Moreover, the significant lack of P2Y1 G allele homozygotes in the SIDS (show IDS Antibodies) group shows that respiratory response plays an important role in the etiology of SIDS (show IDS Antibodies)
The physiological impact of A87T mutation of the P2Y11 (show P2RY11 Antibodies) receptor derives from detrimental effects on P2Y1-P2Y11 (show P2RY11 Antibodies) receptor interaction.
Low ATP concentrations potentiated epinephrine-induced platelet aggregation that was abolished by P2Y1 antagonist MRS2500 suggesting P2Y1 receptor activation due to contaminating ADP.
P2Y1 receptor-mediated responses involve Flt3 (show FLT3 Antibodies) transactivation, and may identify a unique mechanism whereby cancer chemotherapy with receptor tyrosine kinase (show RET Antibodies) inhibitors promotes vascular dysfunction.
Purinergic P2Y1 receptor signaling mediates wound stimuli-induced cyclooxygenase-2 (show PTGS2 Antibodies) expression in intestinal subepithelial myofibroblasts.
P2Y1 and P2Y13 (show P2RY13 Antibodies) receptors play a major role in vasa (show DDX4 Antibodies) vasorum endothelial cells growth responses.
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
, P2Y purinoceptor 1
, P2Y1 receptor
, P2Y1 purinoceptor
, P2 purinoceptor subtype Y1
, platelet ADP receptor
, P2 purinoreceptor subclass 2Y
, P2Y ATP receptor 1
, ATP receptor P2Y1
, G protein-coupled receptor
, p2y1 purinoceptor