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Purinergic Receptor P2Y, G-Protein Coupled, 14 Proteins (P2RY14)

The product of P2RY14 belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. Additionally we are shipping P2RY14 Antibodies (60) and P2RY14 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
P2RY14 9934 Q15391
P2RY14 140795 Q9ESG6
Rat P2RY14 P2RY14 171108 O35881
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Top P2RY14 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$823.90
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$999.22
Details

P2RY14 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14) Interaction Partners

Human Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14) interaction partners

  1. UDP-glucose (show UGCG Proteins) activates P2Y14 receptor and JAK2 (show JAK2 Proteins), increases STAT3 (show STAT3 Proteins) Tyr705 phosphorylation, and enhances transcription of HAS2 (show HAS2 Proteins).

  2. PPTN as a highly selective high-affinity antagonist of the P2Y14-R.

  3. These results support the notion that UDP-glucose (show UGCG Proteins) is a stable and potent proinflammatory mediator that promotes P2Y (show P2RY1 Proteins)(14)-R-mediated neutrophil motility via Rho/Rho kinase (show ROCK1 Proteins) activation.

  4. The IUPHAR Subcommittee for P2Y (show P2RY1 Proteins) receptor nomenclature and classification reviews the current knowledge of the UDP-glucose receptor and presents reasons for including it in the P2Y (show P2RY1 Proteins) receptor family as the P2Y(14) receptor.

  5. a G-protein-coupled receptor (show ADRA1A Proteins) identifying a quiescent, primitive population of hematopoietic cells restricted to bone marrow; it mediates primitive cell responses to specific hematopoietic microenvironments

  6. Discrete expression of GPR105 demonstrated within the immature subset of monocyte-derived dendritic cells (DC) suggests a possible role for this receptor in DC activation.

  7. We have demonstrated the presence of P2Y(14) receptor protein in platelets, but no contribution of this receptor to several measures of platelet function has been observed

  8. UDP-glucose (show UGCG Proteins) stimulated IL-8 production via P2RY14 in human endometrial epithelial cells but not stromal cells

Mouse (Murine) Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14) interaction partners

  1. Insulin (show INS Proteins) secretion tests revealed a reduced insulin (show INS Proteins) release from P2Y14-deficient islets, highlighting P2Y14 as a new modulator of proper insulin (show INS Proteins) secretion

  2. the physiological importance of P2Y14 receptors in the vasculature

  3. P2Y14 on stem/progenitor cells of the hematopoietic system inhibits cell senescence by monitoring and responding to the extracellular manifestations of tissue stress

  4. Results suggest that P2Y14 may act as the receptor for UDP-sugars in osteoclast precusors and may regulate RANKL (show TNFSF11 Proteins)-induced osteoclastogenesis.

  5. P2Y14 is a receptor governing in utero tolerance to genotoxic stress.

  6. These studies indicate that GPR105 ablation mitigates high fat diet-induced insulin (show INS Proteins) resistance by inhibiting macrophage recruitment and tissue inflammation

  7. Data detected mRNA and protein for ADP receptors P2Y12 and P2Y13 in mouse dorsal root ganglia (DRG). P2Y14, a homologous Gi-coupled nucleotide receptor, is also expressed in DRG.

  8. These results demonstrate a novel function of the P2Y14 receptor in the rodent stomach and an ability of UDP-glucose (show UGCG Proteins) to delay gastric emptying without involving the P2Y14 receptor.

  9. UDP-glucose (show UGCG Proteins) and its receptor P2RY14 are key front line players able to trigger innate mucosal immune responses in the FRT bypassing the recognition of pathogen-associated molecular patterns

P2RY14 Protein Profile

Protein Summary

The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.

Gene names and symbols associated with P2RY14

  • purinergic receptor P2Y, G-protein coupled, 14 (P2RY14)
  • purinergic receptor P2Y, G-protein coupled, 14 (P2ry14)
  • A330108O13Rik protein
  • BPR105 protein
  • Gpr105 protein
  • P2Y14 protein

Protein level used designations for P2RY14

purinergic receptor P2Y, G-protein coupled, 14 , G protein coupled receptor for UDP-glucose , G protein-coupled receptor 105 , G-protein coupled receptor 105 , P2Y purinoceptor 14 , P2Y(14) receptor , P2Y14 receptor , UDP-glucose receptor , G protein-coupled receptor VTR 15-20 , P2Y14 , VTR 15-20

GENE ID SPECIES
425039 Gallus gallus
9934 Homo sapiens
140795 Mus musculus
171108 Rattus norvegicus
767936 Bos taurus
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