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The protein encoded by PPA2 is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. Additionally we are shipping PPA2 Proteins (7) and many more products for this protein.
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Schizosaccharomyces pombe Polyclonal PPA2 Primary Antibody for IF, IP - ABIN2452079
Kinoshita, Yamano, Niwa, Yoshida, Yanagida: Negative regulation of mitosis by the fission yeast protein phosphatase ppa2. in Genes & development 1993
Show all 2 references for ABIN2452079
Single nucleotide polymorphisms in PPA2 is associated with response to antipsychotic agents in schizophrenia.
We think that PP2A (show PPP2R4 Antibodies) can be one of the key components to regulate the fusion of various endocytotic compartments and /or the trafficking along the microtubules.
No pathogenic mutations were identified in the PPA2 gene in patients with mitochondrial DNA depletion syndromes (MDS (show PAFAH1B1 Antibodies)).
downregulation of protein phosphatase 2 activity in PINK1 (show PINK1 Antibodies)-silenced cells promotes the protective effect of autophagy through phosphorylation of Bcl-2 (show BCL2 Antibodies)
The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
, inorganic pyrophosphatase 2, mitochondrial
, pyrophosphatase SID6-306
, pyrophosphate phospho-hydrolase 2