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anti-Pyrroline-5-Carboxylate Reductase 1 (PYCR1) Antibodies

PYCR1 encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. Additionally we are shipping Pyrroline-5-Carboxylate Reductase 1 Proteins (14) and Pyrroline-5-Carboxylate Reductase 1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PYCR1 5831 P32322
PYCR1 209027 Q922W5
PYCR1 287877  
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Top anti-Pyrroline-5-Carboxylate Reductase 1 Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PYCR1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PYCR1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram) using PYCR1  Antibody (C-term), followed by FITC-conjugated goat-anti-rabbit secondary antibodies. Immunohistochemistry analysis in colon carcinoma (Formalin-fixed, Paraffin-embedded) using PYCR1  Antibody (C-term), followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PYCR1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB PYCR1 Antibody (C-term) (ABIN653849) western blot analysis in K562,WiDr,HepG2 cell line lysates (35 µg/lane).This demonstrates the PYCR1 antibody detected the PYCR1 protein (arrow). PYCR1 Antibody (C-term) (ABIN653849) IHC analysis in formalin fixed and paraffin embedded colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of PYCR1 expression in transfected 293T cell line by PYCR1 MaxPab polyclonal antibody.Lane 1: PYCR1 transfected lysate(35.09 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to PYCR1 on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB PYCR1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated WB PYCR1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit APC FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IP, WB PYCR1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PYCR1 expression in HepG2. Immunoprecipitation of PYCR1 transfected lysate using anti-PYCR1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with PYCR1 purified MaxPab mouse polyclonal antibody (B01P) . 100 μL Log in to see 9 Days
$418.57
Details

PYCR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
,

, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-Pyrroline-5-Carboxylate Reductase 1 Antibodies

  1. Human Polyclonal PYCR1 Primary Antibody for FACS, IHC (p) - ABIN954393 : Reversade, Escande-Beillard, Dimopoulou, Fischer, Chng, Li, Shboul, Tham, Kayserili, Al-Gazali, Shahwan, Brancati, Lee, OConnor, Schmidt-von Kegler, Merriman, Nelson, Masri, Alkazaleh, Guerra et al.: Mutations in PYCR1 cause cutis laxa with progeroid features. ... in Nature genetics 2009 (PubMed)
    Show all 3 references for ABIN954393

  2. Cow (Bovine) Polyclonal PYCR1 Primary Antibody for WB - ABIN2787369 : Meng, Lou, Liu, Li, Zhao, Bartlam, Rao: Crystal structure of human pyrroline-5-carboxylate reductase. in Journal of molecular biology 2006 (PubMed)

  3. Human Polyclonal PYCR1 Primary Antibody for IF, WB - ABIN519565 : De Ingeniis, Ratnikov, Richardson, Scott, Aza-Blanc, De, Kazanov, Pellecchia, Ronai, Osterman, Smith: Functional specialization in proline biosynthesis of melanoma. in PLoS ONE 2012 (PubMed)

More Antibodies against Pyrroline-5-Carboxylate Reductase 1 Interaction Partners

Human Pyrroline-5-Carboxylate Reductase 1 (PYCR1) interaction partners

  1. confirming that indeed PYCR1 generates L-pipecolic acid from Delta(1)-piperideine-6-carboxylate

  2. our current study presents the second largest group of patients with PYCR1-related ARCL (show ATP6V0A2 Antibodies) and expands the clinical and genetic spectrum.

  3. Identification of two new mutations in the PYCR1 gene in patients with autosomal recessive cutis laxa, type 2.

  4. Data suggest that DJ-1 (show PARK7 Antibodies) and PYCR1 are on the same pathway of anti-oxidative stress protection of the cells.

  5. The findings presented here suggest a mutation screening of PYCR1 and cardiovascular survey in patients with De Barsy syndrome (DBS (show MCF2L Antibodies)).

  6. Mutation analysis revealed the presence of disease-causing variants in PYCR1, including a novel deletion of the entire PYCR1 gene in one family, and in each of the other patients the homozygous missense mutations.

  7. A novel mutation in PYCR1 causes an autosomal recessive cutis laxa with premature aging features in a family.

  8. The phenotype caused by PYCR1 mutations corresponds to geroderma osteodysplasticum rather than ARCL2B.

  9. Mutagenesis and kinetic studies reveal the pivotal roles of the dinucleotide-binding Rossmann motif and residue Glu221 in the human enzyme Pyrroline-5-carboxylate reductase (show PYCR2 Antibodies)(P5CR).

  10. In Autosomal-recessive cutis laxa type 2, a single nucleotide change leads to a missense mutation adjacent to a splice junction in the gene encoding PYCR1.

Pyrroline-5-Carboxylate Reductase 1 (PYCR1) Antigen Profile

Protein Summary

This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms.

Gene names and symbols associated with PYCR1

  • pyrroline-5-carboxylate reductase family, member 1 (pycr1) antibody
  • pyrroline-5-carboxylate reductase 1 (PYCR1) antibody
  • pyrroline-5-carboxylate reductase 1 (Pycr1) antibody
  • pyrroline-5-carboxylate reductase 1 (pycr1) antibody
  • ARCL2B antibody
  • ARCL3B antibody
  • P5C antibody
  • P5CR antibody
  • PIG45 antibody
  • PP222 antibody
  • PRO3 antibody
  • PYCR antibody
  • zgc:73112 antibody

Protein level used designations for PYCR1

P5C reductase 1 , mitochondrial pyrroline-5-carboxylate reductase 1 , proliferation-inducing protein 45 , pyrroline-5-carboxylate reductase 1, mitochondrial , P5CR 1

GENE ID SPECIES
432159 Xenopus laevis
5831 Homo sapiens
209027 Mus musculus
287877 Rattus norvegicus
393799 Danio rerio
483372 Canis lupus familiaris
539606 Bos taurus
Selected quality suppliers for anti-Pyrroline-5-Carboxylate Reductase 1 (PYCR1) Antibodies
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