You are viewing an incomplete version of our website. Please click to reload the website as full version.

Pyrroline-5-Carboxylate Reductase 1 Proteins (PYCR1)

PYCR1 encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. Additionally we are shipping Pyrroline-5-Carboxylate Reductase 1 Antibodies (52) and Pyrroline-5-Carboxylate Reductase 1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PYCR1 5831 P32322
PYCR1 209027 Q922W5
Rat PYCR1 PYCR1 287877  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Pyrroline-5-Carboxylate Reductase 1 Proteins at antibodies-online.com

Showing 9 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,856.33
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$5,769.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$467.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated   2 μg Log in to see 6 Days
$168.54
Details

PYCR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced Pyrroline-5-Carboxylate Reductase 1 Proteins

  1. Human PYCR1 Protein expressed in Escherichia coli (E. coli) - ABIN667842 : Reversade, Escande-Beillard, Dimopoulou, Fischer, Chng, Li, Shboul, Tham, Kayserili, Al-Gazali, Shahwan, Brancati, Lee, OConnor, Schmidt-von Kegler, Merriman, Nelson, Masri, Alkazaleh, Guerra et al.: Mutations in PYCR1 cause cutis laxa with progeroid features. ... in Nature genetics 2009 (PubMed)
    Show all 2 references for ABIN667842

More Proteins for Pyrroline-5-Carboxylate Reductase 1 (PYCR1) Interaction Partners

Human Pyrroline-5-Carboxylate Reductase 1 (PYCR1) interaction partners

  1. confirming that indeed PYCR1 generates L-pipecolic acid from Delta(1)-piperideine-6-carboxylate

  2. our current study presents the second largest group of patients with PYCR1-related ARCL (show ATP6V0A2 Proteins) and expands the clinical and genetic spectrum.

  3. Identification of two new mutations in the PYCR1 gene in patients with autosomal recessive cutis laxa, type 2.

  4. Data suggest that DJ-1 (show PARK7 Proteins) and PYCR1 are on the same pathway of anti-oxidative stress protection of the cells.

  5. The findings presented here suggest a mutation screening of PYCR1 and cardiovascular survey in patients with De Barsy syndrome (DBS (show MCF2L Proteins)).

  6. Mutation analysis revealed the presence of disease-causing variants in PYCR1, including a novel deletion of the entire PYCR1 gene in one family, and in each of the other patients the homozygous missense mutations.

  7. A novel mutation in PYCR1 causes an autosomal recessive cutis laxa with premature aging features in a family.

  8. The phenotype caused by PYCR1 mutations corresponds to geroderma osteodysplasticum rather than ARCL2B.

  9. Mutagenesis and kinetic studies reveal the pivotal roles of the dinucleotide-binding Rossmann motif and residue Glu221 in the human enzyme Pyrroline-5-carboxylate reductase (show PYCR2 Proteins)(P5CR).

  10. In Autosomal-recessive cutis laxa type 2, a single nucleotide change leads to a missense mutation adjacent to a splice junction in the gene encoding PYCR1.

Pyrroline-5-Carboxylate Reductase 1 (PYCR1) Protein Profile

Protein Summary

This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms.

Gene names and symbols associated with PYCR1

  • pyrroline-5-carboxylate reductase family, member 1 (pycr1)
  • pyrroline-5-carboxylate reductase 1 (PYCR1)
  • pyrroline-5-carboxylate reductase 1 (Pycr1)
  • pyrroline-5-carboxylate reductase 1 (pycr1)
  • ARCL2B protein
  • ARCL3B protein
  • P5C protein
  • P5CR protein
  • PIG45 protein
  • PP222 protein
  • PRO3 protein
  • PYCR protein
  • zgc:73112 protein

Protein level used designations for PYCR1

P5C reductase 1 , mitochondrial pyrroline-5-carboxylate reductase 1 , proliferation-inducing protein 45 , pyrroline-5-carboxylate reductase 1, mitochondrial , P5CR 1

GENE ID SPECIES
432159 Xenopus laevis
5831 Homo sapiens
209027 Mus musculus
287877 Rattus norvegicus
393799 Danio rerio
483372 Canis lupus familiaris
539606 Bos taurus
Selected quality suppliers for Pyrroline-5-Carboxylate Reductase 1 Proteins (PYCR1)
Did you look for something else?