Pyrroline-5-Carboxylate Reductase 1 Proteins (PYCR1)

PYCR1 encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. Additionally we are shipping Pyrroline-5-Carboxylate Reductase 1 Antibodies (57) and Pyrroline-5-Carboxylate Reductase 1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PYCR1 5831 P32322
PYCR1 209027 Q922W5
Rat PYCR1 PYCR1 287877  
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Top Pyrroline-5-Carboxylate Reductase 1 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 2 to 3 Days
$375.00
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 15 to 19 Days
$407.00
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,856.33
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 2 to 3 Days
$5,769.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$467.86
Details
Human Un-conjugated   2 μg Log in to see 6 Days
$168.54
Details

PYCR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Pyrroline-5-Carboxylate Reductase 1 (PYCR1) Interaction Partners

Human Pyrroline-5-Carboxylate Reductase 1 (PYCR1) interaction partners

  1. these findings revealed that the mRNA and protein PYCR1 levels were significantly related to the poor outcome in either ER-negative or ER-positive breast cancer. PYCR1 could serve as a prognostic biomarker, therapeutic target and predictive biomarker for breast cancers.

  2. PYCR1 forms a concentration-dependent decamer in solution, consistent with the pentamer-of-dimers assembly seen crystallographically

  3. Authors found that PYCR1 was highly expressed in prostate cancer tissues and then knocked down PYCR1 in PCa (show FLVCR1 Proteins) cell lines (DU145, PC-3 (show PCSK1 Proteins) and LNCap) via lentivirus-mediated gene delivery and analyzed its biological function.

  4. Silencing of both PYCR1 and PYCR2 (show PYCR2 Proteins) completely abolished anti-oxidation activity of RRM2B (show RRM2B Proteins), demonstrating a functional collaboration of these metabolic enzymes in response to oxidative stress.

  5. confirming that indeed PYCR1 generates L-pipecolic acid from Delta(1)-piperideine-6-carboxylate

  6. our current study presents the second largest group of patients with PYCR1-related ARCL (show ATP6V0A2 Proteins) and expands the clinical and genetic spectrum.

  7. Identification of two new mutations in the PYCR1 gene in patients with autosomal recessive cutis laxa, type 2.

  8. Data suggest that DJ-1 (show PARK7 Proteins) and PYCR1 are on the same pathway of anti-oxidative stress protection of the cells.

  9. The findings presented here suggest a mutation screening of PYCR1 and cardiovascular survey in patients with De Barsy syndrome (DBS (show MCF2L Proteins)).

  10. Mutation analysis revealed the presence of disease-causing variants in PYCR1, including a novel deletion of the entire PYCR1 gene in one family, and in each of the other patients the homozygous missense mutations.

Mouse (Murine) Pyrroline-5-Carboxylate Reductase 1 (PYCR1) interaction partners

  1. susceptibility to experimental pancreatitis is determined by strain and model differences with Clusterin (show CLU Proteins) and Pycr1 alterations

Pyrroline-5-Carboxylate Reductase 1 (PYCR1) Protein Profile

Protein Summary

This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms.

Gene names and symbols associated with PYCR1

  • pyrroline-5-carboxylate reductase family, member 1 (pycr1)
  • pyrroline-5-carboxylate reductase 1 (PYCR1)
  • pyrroline-5-carboxylate reductase 1 (Pycr1)
  • pyrroline-5-carboxylate reductase 1 (pycr1)
  • ARCL2B protein
  • ARCL3B protein
  • P5C protein
  • P5CR protein
  • PIG45 protein
  • PP222 protein
  • PRO3 protein
  • PYCR protein
  • zgc:73112 protein

Protein level used designations for PYCR1

P5C reductase 1 , mitochondrial pyrroline-5-carboxylate reductase 1 , proliferation-inducing protein 45 , pyrroline-5-carboxylate reductase 1, mitochondrial , P5CR 1

GENE ID SPECIES
432159 Xenopus laevis
5831 Homo sapiens
209027 Mus musculus
287877 Rattus norvegicus
393799 Danio rerio
483372 Canis lupus familiaris
539606 Bos taurus
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