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anti-Pyruvate Dehydrogenase Phosphatase (PDP) Antibodies

Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Additionally we are shipping Pyruvate Dehydrogenase Phosphatase Kits (35) and Pyruvate Dehydrogenase Phosphatase Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDP 11801 Q9QWK4
PDP 54705  
PDP 54704 Q9P0J1
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Top anti-Pyruvate Dehydrogenase Phosphatase Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB PDP1 Antibody (Center) (ABIN656386) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with PDP1 Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of PDP1 Antibody (Center) in Jurkat,HepG2,293 cell line lysates (35ug/lane). This demonstrates the PDP1 antibody detected the PDP1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Cow Rabbit Un-conjugated WB Western blot analysis of PDP1 expression in A549 (A), NS-1 (B), MCF7 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$347.60
Details
Human Rabbit PE IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

PDP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Pyruvate Dehydrogenase Phosphatase Antibodies

  1. Human Polyclonal PDP Primary Antibody for EIA, IHC (p) - ABIN954075 : Kato, Kato: Crystallization and preliminary crystallographic studies of the catalytic subunits of human pyruvate dehydrogenase phosphatase isoforms 1 and 2. in Acta crystallographica. Section F, Structural biology and crystallization communications 2010 (PubMed)
    Show all 3 references for ABIN954075

  2. Human Polyclonal PDP Primary Antibody for IHC (p), WB - ABIN656386 : Shan, Kang, Elf, Xie, Gu, Aguiar, Lonning, Hitosugi, Chung, Arellano, Khoury, Shin, Khuri, Boggon, Fan: Tyr-94 phosphorylation inhibits pyruvate dehydrogenase phosphatase 1 and promotes tumor growth. in The Journal of biological chemistry 2014 (PubMed)

More Antibodies against Pyruvate Dehydrogenase Phosphatase Interaction Partners

Mouse (Murine) Pyruvate Dehydrogenase Phosphatase (PDP) interaction partners

  1. AIM enhances intratubular debris clearance and ameliorates acute kidney injury via interaction with KIM-1 (show HAVCR1 Antibodies).

  2. CD5L (show CD5L Antibodies) as a critical regulator that distinguishes Th17 functional states and identified T cell lipid metabolism as an integral component of the pathways regulating Th17 cell pathogenicity.

  3. the assembled p40 (show LANCL1 Antibodies)-CD5L (show CD5L Antibodies) heterodimer does not recapitulate the biological activity of IL-12 (show IL12A Antibodies).

  4. AIM-IgM association plays a critical role in the obesity-associated autoimmune process.

  5. AIM binds to cytosolic FAS (show FAS Antibodies) protein at various regions responsible for elongation of fatty acids, release of synthesized palmitate, and stabilization of FAS (show FAS Antibodies) dimerization.

  6. The protein inhibits apoptosis of T cells and NKT (show CTSL1 Antibodies) cells in Corynebacterium-induced granuloma formation in mice.

  7. Bacterial lipoteichoic acid might affect the pathogenesis of epithelial inflammation followed by fibrosis in systemic multifocal epithelial inflammations in chronic colitis-harboring TCR alpha(-/-) x AIM(-/-) mice

  8. defects in PP2Cm (show PPM1K Antibodies) may be responsible for a subset of human maple syrup urine disease

Human Pyruvate Dehydrogenase Phosphatase (PDP) interaction partners

  1. YB-1 (show YBX1 Antibodies) phosphorylation at Ser (show SIGLEC1 Antibodies)-102 is an important prerequisite for CCL5 (show CCL5 Antibodies) promoter activation during macrophage differentiation

  2. the pyruvate dehydrogenase complex is regulated by Tyr (show TYR Antibodies) phosphorylation of PDP1, which toggles recruitment between ACAT1 (show ACAT1 Antibodies) and SIRT3 (show SIRT3 Antibodies)

  3. Although 7 days of bed rest induced whole body glucose intolerance, exercise-induced PDH regulation in skeletal muscle was not changed, suggesting that exercise-induced PDH regulation in skeletal muscle is maintained in glucose-intolerant individuals.

  4. catalytic subunit of PDP1 crystals belonged to space group P4(1)2(1)2 or P4(3)2(1)2, with unit-cell parameters a = b = 65.1, c = 216.1 A.

  5. pyruvate dehydrogenase phosphatase PDP1 is down-regulated in circulating lymphocytes of obese subjects because it is poorly sensitive to magnesium/calcium; this defect is attenuated when plasma insulin (show INS Antibodies) is greatly enhanced

  6. Lower accumulation of free ADP and AMP (show APRT Antibodies) after the FAT-adapt trial may be responsible for the decreased glycogenolysis and PDH activation during sprinting.

  7. In cultured skin fibroblasts from three patients with congenital lactic acidemia due to a defect in activation of the pyruvate dehydrogenase complex, the PDP-activity was significantly reduced to 50.7%, 64.6% and 63.1% of that of control fibroblasts.

  8. In postmortem tissue samples, from male child with metabolic acidosis, PDK (show PDK2 Antibodies) normally reduced PDH-activity in ATP-presence. Addition of Ca++ and Mg++ did not restored PDH-activity. The defect was attributed to a markedly reduced PDP-activity.

Pyruvate Dehydrogenase Phosphatase (PDP) Antigen Profile

Protein Summary

Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported\; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with PDP

  • lethal (1) G0334 (l(1)G0334) antibody
  • Pyruvate dehydrogenase [acetyl-transferring]-phosphatase 1-like (LOC100153002) antibody
  • Pyruvate dehydrogenase phosphatase (Pdp) antibody
  • pyruvate dehydrogenase phosphatase (Pdp) antibody
  • CD5 antigen-like (Cd5l) antibody
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (Pdp1) antibody
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1) antibody
  • 1/6 antibody
  • 153332_at antibody
  • AAC-11 antibody
  • AI047839 antibody
  • Api6 antibody
  • CG7010 antibody
  • CG 7010 antibody
  • CG12151 antibody
  • CT2 antibody
  • Dmel\\CG7010 antibody
  • Dmel\\CG12151 antibody
  • Gm1024 antibody
  • L(1)g0334 antibody
  • l (1) G0334 antibody
  • PDH antibody
  • Pdp antibody
  • PDPC antibody
  • PPM2C antibody
  • Sp-alpha antibody

Protein level used designations for PDP

CG7010-PA , CG7010-PB , CG7010-PC , CG7010-PD , l(1)G0334-PA , l(1)G0334-PB , l(1)G0334-PC , l(1)G0334-PD , pyruvate dehydrogenase , CG12151-PA , CG12151-PB , Pdp-PA , Pdp-PB , pyruvate dehydrogenase phosphatase , AIM/Spalpha , CT-2 , Pdp 1/6 , apoptosis inhibitor 6 , apoptosis inhibitor expressed by macrophages , PDP 1 , PDPC 1 , [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial , protein phosphatase 2C, magnesium dependent, catalytic subunit , pyruvate dehydrogenase phosphatase catalytic subunit 1 , pyruvate dehydrogenase phosphatase isoenzyme 2 , protein phosphatase 2C, magnesium-dependent, catalytic subunit , pyruvate dehydrogenase phosphatase isoenzyme 1 , pyruvate dehydrogenase phosphatase, catalytic subunit 1 , pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase

GENE ID SPECIES
31406 Drosophila melanogaster
100153002 Sus scrofa
31683 Drosophila melanogaster
413080 Apis mellifera
11801 Mus musculus
381511 Mus musculus
54705 Rattus norvegicus
54704 Homo sapiens
477941 Canis lupus familiaris
280891 Bos taurus
Selected quality suppliers for anti-Pyruvate Dehydrogenase Phosphatase (PDP) Antibodies
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