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anti-Pyruvate Dehydrogenase beta (PDHB) Antibodies

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid. Additionally we are shipping Pyruvate Dehydrogenase beta Proteins (15) and Pyruvate Dehydrogenase beta Kits (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDHB 5162 P11177
PDHB 289950 P49432
PDHB 68263 Q9D051
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Top anti-Pyruvate Dehydrogenase beta Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to PDHB on formalin-fixed paraffin-embedded human heart. [antibody concentration 3 ug/ml] PDHB monoclonal antibody (M03), clone 2B2 Western Blot analysis of PDHB expression in HeLa . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated WB PDHB monoclonal antibody (M03), clone 2B2 Western Blot analysis of PDHB expression in HeLa on formalin-fixed paraffin-embedded human heart (antibody concentration 3 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$365.20
Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$376.20
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Rabbit Un-conjugated WB PDHB antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details

PDHB Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Pyruvate Dehydrogenase beta Antibodies

  1. Cow (Bovine) Polyclonal PDHB Primary Antibody for WB - ABIN2783247 : Okajima, Korotchkina, Prasad, Rupar, Phillips, Ficicioglu, Hertecant, Patel, Kerr: Mutations of the E1beta subunit gene (PDHB) in four families with pyruvate dehydrogenase deficiency. in Molecular genetics and metabolism 2008 (PubMed)

  2. Human Polyclonal PDHB Primary Antibody for IF (p), IHC (p) - ABIN752833 : Xing, Yuan, Xu, Gu, Liang, Lu: Proteomic identification of mitochondrial targets involved in andrographolide sodium bisulfite-induced nephrotoxicity in a rat model. in Environmental toxicology and pharmacology 2015 (PubMed)

  3. Human Monoclonal PDHB Primary Antibody for IHC (p), ELISA - ABIN562157 : Coupland, Vorum, Mandal, Kalirai, Honoré, Urbak, Lake, Dopierala, Damato: Proteomics of uveal melanomas suggests HSP-27 as a possible surrogate marker of chromosome 3 loss. in Investigative ophthalmology & visual science 2010 (PubMed)

More Antibodies against Pyruvate Dehydrogenase beta Interaction Partners

Human Pyruvate Dehydrogenase beta (PDHB) interaction partners

  1. Data indicate that (pro)renin receptor (show ATP6AP2 Antibodies) ATP6PA2 interacts with the E1 beta subunit (show POLG Antibodies) of pyruvate dehydrogenase (show PDP Antibodies) and controlling its protein stability

  2. PHD3 (show EGLN3 Antibodies) depletion did not affect the expression of the PDH (show PDP Antibodies)-E1alpha, E1beta, and E2 subunits, or the phosphorylation status of E1alpha, but destabilized the PDH (show PDP Antibodies) complex (PDC (show PNKD Antibodies)), resulting in less functional PDC (show PNKD Antibodies).

  3. Sequencing of PDHB reveals a homozygous point mutation (c.302T>C), causing a predicted amino acid change in patient 1. Patient 2 is compound heterozygote for mutations c.301A>G (p.M101V) and c.313G>A (p.R105Q).

  4. Data indicate that PDH (show PDP Antibodies) deficiency in our patient involves a post-translational modification in which EGFR (show EGFR Antibodies)-PTK-mediated tyrosine phosphorylation of the E1beta protein leads to enhanced ubiquitination followed by proteasome-mediated degradation.

  5. clinical findings are similar to those of PDHA1 (show PDHA1 Antibodies) deficiency, except that ataxia (show USP14 Antibodies) was more frequent in PDHA1 (show PDHA1 Antibodies) cases and consanguinity was found only in PDHB families.

  6. Species specificity in the interaction between hE1beta and hE2 (show SPAG11B Antibodies) in pyruvate dehydrogenase (show PDP Antibodies) complex.

Cow (Bovine) Pyruvate Dehydrogenase beta (PDHB) interaction partners

  1. Polymorphisms in promoter regions of PDHB, SORBS1 (show SORBS1 Antibodies), and EDG1 (show S1PR1 Antibodies) genes showing marbling-associated expression changes.

Mouse (Murine) Pyruvate Dehydrogenase beta (PDHB) interaction partners

  1. PHD3 (show EGLN3 Antibodies) depletion did not affect the expression of the PDH (show PDP Antibodies)-E1alpha, E1beta, and E2 subunits, or the phosphorylation status of E1alpha, but destabilized the PDH (show PDP Antibodies) complex (PDC (show PDC Antibodies)), resulting in less functional PDC (show PDC Antibodies).

Pyruvate Dehydrogenase beta (PDHB) Antigen Profile

Protein Summary

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with PDHB

  • CG11876 gene product from transcript CG11876-RA (CG11876) antibody
  • pyruvate dehydrogenase (lipoamide) beta (pdhb) antibody
  • pyruvate dehydrogenase (lipoamide) beta (PDHB) antibody
  • pyruvate dehydrogenase (lipoamide) beta (Pdhb) antibody
  • 2610103L06Rik antibody
  • AL024199 antibody
  • C81408 antibody
  • CG 11876 antibody
  • Dmel\\CG11876 antibody
  • E1beta antibody
  • PDHB antibody
  • PDHBD antibody
  • PDHE1-B antibody
  • PHE1B antibody
  • wu:fc76a05 antibody
  • zgc:64062 antibody

Protein level used designations for PDHB

CG11876-PA , CG11876-PB , CG11876-PC , CG11876-PD , pyruvate dehydrogenase E1beta subunit , DKEYP-87E7.2 , nir , noir , pyruvate dehydrogenase E1 component subunit beta, mitochondrial , pyruvate dehydrogenase, E1 beta polypeptide , PDHE1-B

GENE ID SPECIES
43437 Drosophila melanogaster
406428 Danio rerio
100050581 Equus caballus
5162 Homo sapiens
289950 Rattus norvegicus
476574 Canis lupus familiaris
613610 Bos taurus
68263 Mus musculus
100171772 Pongo abelii
Selected quality suppliers for anti-Pyruvate Dehydrogenase beta (PDHB) Antibodies
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