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QPRT encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Additionally we are shipping QPRT Antibodies (62) and QPRT Kits (5) and many more products for this protein.
Showing 10 out of 17 products:
Human QPRT Protein expressed in Escherichia coli (E. coli) - ABIN667206
Delaney, Hodson, Thakkar, Connor, Sweatman, Kenny, McGill, Holder, Hutton, Haselden, Waterfield: Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation. in Archives of toxicology 2005
Show all 2 references for ABIN667206
Report of the crystal structure of human QPRT bound to its inhibitor phthalic acid (PHT) and kinetic analysis of PHT inhibition of human QPRT.
QPRT is a potential new marker for the immunohistochemical screening of follicular thyroid nodules.
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.
, nicotinate-nucleotide pyrophosphorylase (carboxylating)
, nicotinate-nucleotide pyrophosphorylase [carboxylating]
, nicotinate-nucleotide pyrophosphorylase
, quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating))