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anti-R-Spondin 2 (RSPO2) Antibodies

R-spondins (RSPOs), such as RSPO2, are secreted proteins that regulate beta-catenin (CTNNB1\\\\; MIM 116806) signaling (Kim et al., 2006 [PubMed 16357527]).[supplied by OMIM, Mar 2008].. Additionally we are shipping R-Spondin 2 Proteins (9) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RSPO2 500863  
RSPO2 340419 Q6UXX9
RSPO2 239405 Q8BFU0
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Top anti-R-Spondin 2 Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p) RSPO2 Antibody (C-term) (ABIN651457) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining RSPO2 Antibody (C-term) (ABIN651457) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit APC FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated FACS, ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Rabbit Un-conjugated FACS, IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit APC FACS, IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit HRP IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit FITC FACS, IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit PE FACS, IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

RSPO2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human , ,


, , , , ,
Mouse (Murine)


More Antibodies against R-Spondin 2 Interaction Partners

Human R-Spondin 2 (RSPO2) interaction partners

  1. data reveal a RSPO2-induced, LGR5 (show LGR5 Antibodies)-dependent Wnt (show WNT2 Antibodies) signaling-negative feedback loop that exerts a net growth-suppressive effect on CRC (show CALR Antibodies) cells

  2. results suggest that the expression of RSPO (show RSPO1 Antibodies) fusion transcripts is related to a subset of colorectal cancers arising in the Japanese population

  3. Wnt (show WNT2 Antibodies)(high) cells were more likely to give rise to Wnt (show WNT2 Antibodies)(high) progeny, tended to be more metastatic, and revealed higher levels of RSPO2 expression.

  4. These findings suggest that R-Spondin2 may promote hepatic stellate cell activation by enhancing the canonical Wnt (show WNT2 Antibodies) pathway.

  5. using RNA-seq data, identification of multiple fusion transcripts including recurrent gene fusions involving R-spondin family members RSPO2 and RSPO3 (show RSPO3 Antibodies) that together occur in 10% of colon tumours

  6. Reduced Rspo-2 levels in osteoarthritis osteoblasts are responsible, at least in part, for their reduced Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling and abnormal mineralization.

Mouse (Murine) R-Spondin 2 (RSPO2) interaction partners

  1. Rspo2 activates Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling to reduce Col2a1 (show COL2A1 Antibodies) and Sox9 (show SOX9 Antibodies) and to facilitate differentiation of proliferating chondrocytes into hypertrophic chondrocytes in growth cartilage

  2. High resolution crystal structure of an ectodomain variant of human LGR5 (show LGR5 Antibodies) (hLGR5ecto) complexed with a signalling competent fragment of mouse Rspo2.

  3. The endogenously expressed Lgr4 (show LGR4 Antibodies) may act as an antagonist molecule that helps to fine-tune the R-spondin/norrin (show NDP Antibodies)-mediated Lgr4 (show LGR4 Antibodies)-Wnt (show WNT2 Antibodies) signaling during gonadal development.

  4. These findings suggest that R-Spondin2 may promote hepatic stellate cell activation by enhancing the canonical Wnt (show WNT2 Antibodies) pathway.

  5. identify the transforming growth factor beta antagonist follistatin (show FST Antibodies) as a key mediator of RSPO (show RSPO1 Antibodies)-LGR4 (show LGR4 Antibodies) signaling in myogenic differentiation

  6. Rspo2 is required to limit the number of outer hair cells to three rows and for optimal arrangement of peripheral nerve fibers in the developing cochlea.

  7. Rspo2 mutation in combination with Rspo3 (show RSPO3 Antibodies) mutation causes severe limb truncation.

  8. Recombinant R-spondin2 and Wnt3a (show WNT3A Antibodies) up- and down-regulate novel target genes in C57MG mouse mammary epithelial cells.

  9. Results indicate that Rspo2 and Wnt1 (show WNT1 Antibodies) have mutually distinct effects on mammary epithelial cell growth and these effects are context-dependent.

  10. Rspo2 is a mesenchyme-derived factor that plays critical roles in regulating branchial arch 1 patterning and morphogenesis through ectodermal-mesenchymal interaction and a novel genetic factor for cleft palate.

R-Spondin 2 (RSPO2) Antigen Profile

Protein Summary

R-spondins (RSPOs), such as RSPO2, are secreted proteins that regulate beta-catenin (CTNNB1\; MIM 116806) signaling (Kim et al., 2006

Gene names and symbols associated with anti-R-Spondin 2 (RSPO2) Antibodies

  • R-spondin 2 (Rspo2) antibody
  • R-spondin 2 (rspo2) antibody
  • R-spondin 2 (RSPO2) antibody
  • R-spondin 2 homolog (Xenopus laevis) (Rspo2) antibody
  • 2610028F08Rik antibody
  • AA673245 antibody
  • CRISTIN2 antibody
  • D430027K22 antibody
  • ftls antibody
  • RGD1562331 antibody

Protein level used designations for anti-R-Spondin 2 (RSPO2) Antibodies

R-spondin-2 , XRspo2 , roof plate-specific spondin-2 , activator of Wnt/beta-catenin pathway , R-spondin 2 homolog , R-spondin 2 , cristin-2 , cysteine-rich and single thrombospondin domain-containing protein 2 , mCristin-2

GENE ID SPECIES
500863 Rattus norvegicus
496383 Xenopus laevis
496854 Xenopus (Silurana) tropicalis
536121 Bos taurus
697376 Macaca mulatta
100056523 Equus caballus
340419 Homo sapiens
239405 Mus musculus
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