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RAB10 belongs to the RAS (see HRAS\; MIM 190020) superfamily of small GTPases. Additionally we are shipping RAB10 Antibodies (68) and RAB10 Proteins (10) and many more products for this protein.
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Rab10 is a target of the GTPase-activating protein (show RASA1 ELISA Kits) AS160, which is inhibited after phosphorylation by the protein kinase (show CDK7 ELISA Kits) Akt (show AKT1 ELISA Kits).
Rab10 silencing increased the plasma membrane residence of HAS3 (show HAS3 ELISA Kits), resulting in a significant increase of hyaluronan secretion and an enlarged cell surface HA coat, whereas Rab10 overexpression suppressed hyaluronan synthesis.
Rab10 regulates endoplasmic reticulum dynamics/morphology. Suggest that these dynamics could be coupled to phospholipid synthesis.
Insulin-stimulated GLUT4 protein translocation in adipocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C
Rab10 and Rab8A (show RAB8A ELISA Kits) are new cytoplasmic factors implicated in WPB biogenesis that play a role in generating granules that can rapidly respond to secretagogue
Rab10, acting upstream of Rab5 (show RAB5A ELISA Kits), plays a prominent role in phagolysosome formation and can modulate Mycobacterium-containing phagosomes maturation
Fibronectin 1 (show FN1 ELISA Kits) and RAB10 show elevated expression in uninvolved psoriatic epidermis.
a related Rab protein, Rab10, can interact with myosin Va, myosin Vb, and myosin Vc
Glut4 (show SLC2A4 ELISA Kits) traffics predominantly through the specialized Rab10-dependent pathway both before and after insulin (show INS ELISA Kits) stimulation.
role of Rab10 in mouse embryo
These results suggest that the association of Rab10-GTP (show AK3 ELISA Kits) with Exoc6 (show EXOC6 ELISA Kits)/6b is a molecular link between insulin (show INS ELISA Kits) signaling and the exocytic machinery in GLUT4 (show SLC2A4 ELISA Kits) translocation.
RAB10 and its GTPase-activating protein (show RASA1 ELISA Kits) AS160 comprise the principal signaling module downstream of insulin receptor (show INSR ELISA Kits) activation that regulates the accumulation of GLUT4 (show SLC2A4 ELISA Kits) transport vesicles at the plasma membrane.
Rab10 coordinates with myosin-Va (show MYO5A ELISA Kits) to mediate the final steps of insulin (show INS ELISA Kits)-stimulated vesicle translocation to the plasma membrane.
show that continuous replenishment of TLR4 (show TLR4 ELISA Kits) from Golgi to plasma membrane is regulated by the small GTPase (show RACGAP1 ELISA Kits) Rab10, which is essential for optimal macrophage activation following ipopolysaccharide stimulation.
Rab10 is a target of AS160 and a positive regulator of GLUT4 (show SLC2A4 ELISA Kits) trafficking to the cell surface upon insulin (show INS ELISA Kits) stimulation.
the subcellular distribution of Rab10, the fraction of Rab10 in the active GTP (show AK3 ELISA Kits) form in vivo; Rab10 participates in GLUT4 (show SLC2A4 ELISA Kits) translocation in 3T3-L1 adipocytes
RAB10 belongs to the RAS (see HRAS\; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998
GTP-binding protein RAB10
, ras-related GTP-binding protein
, ras-related protein Rab-10
, ras-related protein rab10
, rab10 GTP-binding protein