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RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. Additionally we are shipping RAB14 Kits (15) and RAB14 Proteins (10) and many more products for this protein.
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Chicken Polyclonal RAB14 Primary Antibody for IHC, WB - ABIN2792300
Junutula, De Maziére, Peden, Ervin, Advani, van Dijk, Klumperman, Scheller: Rab14 is involved in membrane trafficking between the Golgi complex and endosomes. in Molecular biology of the cell 2004
Show all 3 references for ABIN2792300
PKCiota binds to Rab14 and that PKCiota requires Rab14 for its correct distribution in cells. As with Rab14, PKCiota protects claudin-2 (show CLDN2 Antibodies) from lysosomal degradation and, in consequence, modulates epithelial barrier.
We find that Rab14 indeed binds to RCP, albeit with reduced affinity relative to conventional Rab11-FIP and Rab25-FIP complexes. However, in vivo, Rab11 recruits RCP onto biological membranes.
RAB14 is a direct target of both MIR144 and MIR451. As MIR144 and MIR451 expression increased during human erythropoiesis, RAB14 protein expression decreased. RAB14 as a novel physiological inhibitor of human erythropoiesis.
the miR (show MLXIP Antibodies)-451/RAB14 interaction plays an important role in the enhancement of radiosensitivity in NPC (show NPC1 Antibodies) cells.
Data indicate that myosin Va (show MYO5A Antibodies) interacted with multiple new Rab (show HRB Antibodies) subfamilies including Rab6 (show RAB6A Antibodies), Rab14 and Rab39B (show RAB39B Antibodies).
Rab5a (show RAB5A Antibodies), Rab8a (show RAB8A Antibodies) and Rab14 are major regulators of MT1-MMP (show MMP14 Antibodies) trafficking and invasive migration of primary human macrophages.
Data indicate taht the parasitophorous vacuole (PV), marked with Rab14, Rab30, or Rab43, colocalize with host-derived sphingolipids in the vacuolar space.
findings support a model for HIV-1 Env (show ERVW-1 Antibodies) incorporation in which specific targeting to the particle assembly microdomain on the plasma membrane is mediated by FIP1C and Rab14
FAM116 and Rab14 therefore define an endocytic recycling pathway needed for ADAM protease trafficking and regulation of cell-cell junctions.
Data suggest that targeting with the miR (show MLXIP Antibodies)-451/RAB14 interaction might serve as a novel therapeutic application to treat NSCLC patients.
Rab14 activity promotes phagosome maturation during C. albicans infection but is dysregulated on the phagosome in the presence of the invasive hyphal form, which favors fungal survival and escape.
RAB14 functions upstream of RAB10 (show RAB10 Antibodies) in the sorting of GLUT4 (show SLC2A4 Antibodies) to the specialized transport vesicles that ferry GLUT4 (show SLC2A4 Antibodies) to the plasma membrane.
the primary role of Rab14 in GLUT4 (show SLC2A4 Antibodies) trafficking is to control the transit of internalised GLUT4 (show SLC2A4 Antibodies) from early endosomes into the Golgi complex, rather than direct GLUT4 (show SLC2A4 Antibodies) translocation to the plasma membrane.
Data show that Rinl is closely associated with the cytoskeleton and thus contributes to the spatial control of Rab5a and Rab22 signaling at actin-positive compartments.
The kinesin-3 motor KIF16B (show KIF16B Antibodies)/Rab14 complex acts in biosynthetic Golgi-to-endosome traffic of the fibroblast growth factor receptor (FGFR) during early embryonic development.
Rab14 enables mycobacterial phagosomes to maintain early endosomal characteristics and avoid late endosomal/lysosomal degradative components.
The complete coding sequences of three porcine genes--RAB14, S35A3 and ITM2A (show ITM2A Antibodies) were amplified and nucleotide sequence and tissue expression were analysed.
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004
RAB14, member RAS oncogene family
, rab14, member ras oncogene family
, Ras-related protein Rab-14
, ras-related protein Rab-14
, F protein-binding protein 1
, bA165P4.3 (member RAS oncogene family)
, small GTP binding protein RAB14
, GTPase Rab14
, RAB22, member RAS oncogene family
, ras-related protein Rab-22A