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RAB18, Member RAS Oncogene Family Proteins (RAB18)

The protein encoded by RAB18 is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Additionally we are shipping RAB18 Antibodies (30) and RAB18 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RAB18 22931 Q9NP72
RAB18 19330 P35293
RAB18 307039 Q5EB77
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Top RAB18 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Caenorhabditis elegans His tag   1 mg Log in to see 56 to 66 Days
$2,495.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,495.17
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,495.17
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,495.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$498.21
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RAB18 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced RAB18 Proteins

  1. Human RAB18 Protein expressed in Escherichia coli (E. coli) - ABIN667980 : McMurtrie, Barbosa, Zerial, Kingsmore: Rab17 and rab18, small GTPases with specificity for polarized epithelial cells: genetic mapping in the mouse. in Genomics 1998 (PubMed)
    Show all 2 references for ABIN667980

More Proteins for RAB18, Member RAS Oncogene Family (RAB18) Interaction Partners

Human RAB18, Member RAS Oncogene Family (RAB18) interaction partners

  1. Warburg Micro syndrome is caused by RAB18 deficiency.

  2. findings suggest that RAB18 rs3765133 polymorphism affects the development of specific brain regions, particularly the cerebellum, in healthy people

  3. These results suggest that Rab18 has an important role in viral assembly through the trafficking of the hepatitis C virus core protein to lipid droplets.

  4. High RAB18 expression is associated with glioma.

  5. Rab18-mediated membrane trafficking of FASN (show FASN Proteins) and NS3 facilitates dengue virus replication.

  6. Rab18 and a Rab18 GEF complex of Rab3GAP1 and Rab3GAP2 have roles in the endoplasmic reticulum structure

  7. Rab18 interacts with the HCV nonstructural protein NS5A.

  8. One-hundred and forty-four Micro and nine Martsolf families were investigated, identifying mutations in RAB3GAP1 (show RAB3GAP1 Proteins) in 41% of cases, mutations in RAB3GAP2 in 7% of cases, and mutations in RAB18 in 5% of cases

  9. Hepatitis B virus X protein enhances proliferation of hepatoma cells through Rab18.

  10. Micro syndrome has been associated with causative mutations in three disease genes: RAB3GAP1, RAB3GAP2 and RAB18. Martsolf syndrome has been associated with a mutation in RAB3GAP2. [Review]

Mouse (Murine) RAB18, Member RAS Oncogene Family (RAB18) interaction partners

  1. RAB18 regulates neuronal migration and morphogenesis during development.

  2. Retinoid and cholesterol metabolism are linked in stellate cells by the LD-associated protein Rab18 and may have significant therapeutic benefit in liver fibrosis.

  3. The results of this study indicated that the sensory nervous system is more vulnerable to Rab18 deficiency and WARBM is not only a neurodevelopmental but also neurodegenerative disease.

  4. apparent similarities between the WARBM phenotype and the phenotype that we describe here indicate that the Rab18-mutant mouse provides an important platform for investigation of the disease pathogenesis and therapeutic interventions

  5. Data suggest that overexpression of Rab18 in its GDP-bound state favors peroxisome proliferation in hepatocytes; Rab18 (as well as Rab6 (show RAB6A Proteins), Rab10 (show RAB10 Proteins), and Rab14 (show RAB14 Proteins)) localizes to the peroxisomal compartment.

  6. Rab18 regulates lipid droplet-associated membrane formation

  7. results show that a Rab (show HRB Proteins) protein localizes directly to the monolayer surface of lipid droplets

  8. in neuroendocrine cells, Rab18 acts as a negative regulator of secretory activity, likely by impairing secretory granule transport

RAB18 Protein Profile

Protein Summary

The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with RAB18

  • RAB18, member RAS oncogene family (RAB18)
  • RAB18, member RAS oncogene family (rab18)
  • RAB18, member RAS oncogene family (LOC100219058)
  • RAB18, member RAS oncogene family (LOC100356575)
  • Protein RAB-18 (rab-18)
  • RAB18, member RAS oncogene family (Rab18)
  • AA959686 protein
  • LOC100219058 protein
  • RAB18 protein
  • RAB18LI1 protein
  • WARBM3 protein

Protein level used designations for RAB18

RAB18, member RAS oncogene family , RAB18 small GTPase , Ras-related protein Rab-18 , ras-related protein Rab-18 , GTP-binding protein Rab18

GENE ID SPECIES
282026 Bos taurus
450372 Pan troglodytes
550035 Xenopus (Silurana) tropicalis
708843 Macaca mulatta
100219058 Taeniopygia guttata
100356575 Oryctolagus cuniculus
175272 Caenorhabditis elegans
22931 Homo sapiens
19330 Mus musculus
307039 Rattus norvegicus
420483 Gallus gallus
491408 Canis lupus familiaris
511160 Bos taurus
100174695 Pongo abelii
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