RAB1A, Member RAS Oncogene Family Proteins (RAB1A)

RAB1A encodes a member of the Ras superfamily of GTPases. Additionally we are shipping RAB1A Antibodies (43) and RAB1A Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RAB1A 19324 P62821
RAB1A 5861 P62820
RAB1A 81754 Q6NYB7
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Top RAB1A Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 15 to 19 Days
$319.00
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Dog His tag   1 mg Log in to see 60 to 71 Days
$2,498.83
Details
Yeast Wild boar His tag   1 mg Log in to see 60 to 71 Days
$2,498.83
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,498.83
Details
HOST_Escherichia coli (E. coli) Human GST tag   50 μg Log in to see 11 Days
$313.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$364.64
Details

RAB1A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,
Rat (Rattus)

Top referenced RAB1A Proteins

  1. Human RAB1A Protein expressed in Escherichia coli (E. coli) - ABIN667342 : Zahraoui, Touchot, Chardin, Tavitian: The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion. in The Journal of biological chemistry 1989 (PubMed)
    Show all 2 references for 667342

More Proteins for RAB1A, Member RAS Oncogene Family (RAB1A) Interaction Partners

Zebrafish RAB1A, Member RAS Oncogene Family (RAB1A) interaction partners

  1. The authors demonstrate in zebrafish that nf1 (show NF1 Proteins) loss leads to aberrant activation of RAS signaling in MYCN (show MYCN Proteins)-induced neuroblastomas that arise in these precursors, and that the GTPase-activating protein (GAP)-related domain (GRD) is sufficient to suppress the acceleration of neuroblastoma (show ARHGEF16 Proteins) in nf1 (show NF1 Proteins)-deficient fish, but not the hypertrophy of sympathoadrenal cells in nf1 (show NF1 Proteins) mutant embryos.

  2. Ras activity levels control the repopulation and expansion of adult melanocyte precursors after tissue loss, enabling the recovery of patterned melanocyte stripes during zebrafish appendage regeneration.

Fruit Fly (Drosophila melanogaster) RAB1A, Member RAS Oncogene Family (RAB1A) interaction partners

  1. Drosophila Tempura, a novel protein prenyltransferase alpha subunit, regulates notch signaling via Rab1 and Rab11.

  2. Results suggest a novel function for Rab1a in the regulation of cell migration through controlling integrin beta1 recycling and localization to lipid rafts via a specific downstream effector pathway.

Mouse (Murine) RAB1A, Member RAS Oncogene Family (RAB1A) interaction partners

  1. Rab1A regulates anterograde melanosome transport by recruiting kinesin-1 to melanosomes through interaction with SKIP

  2. These data indicate that AMPylation of Rab1 is an effective strategy to maintain this GTPase (show RACGAP1 Proteins) on the Legionella-containing vacuole membrane.

  3. Rab1A is the first crucial component of the anterograde melanosome transport machinery to be identified in mammalian skin melanocytes.

  4. Acute expression of Rab1 and Rab3d (show RAB3D Proteins) DN constructs partially alleviated this negative feedback mechanism and resulted in impaired ER to Golgi trafficking of procollagen.

  5. Legionella pneumophila SidD catalyzed AMP (show TMPRSS5 Proteins) release from Rab1, generating de-AMPylated Rab1 accessible for inactivation by LepB; identified SidD as missing link connecting processes of early Rab1 accumulation and subsequent removal during infection

  6. Results suggest a novel function for Rab1a in the regulation of cell migration through controlling integrin beta1 recycling and localization to lipid rafts via a specific downstream effector pathway.

  7. Rab1 and Rab6 GTPases may play a role in modulating the function of retina by mediating the transport of nascent proteins along the early secretary pathway, particularly in the process of the light adaptation.

  8. Data show Trs130 (show TRAPPC9 Proteins) (mTrs130) is a component of an analogous TRAPP complex that this complex is enriched on COPI (Coat Protein (show GOLPH3 Proteins) I (show ANXA2 Proteins))-coated vesicles it specifically activates Rab1.

  9. elevated expression of Rab1 protected against alpha-Synuclein-induced dopaminergic neuron loss in animal models of Parkinson Disease

Human RAB1A, Member RAS Oncogene Family (RAB1A) interaction partners

  1. In clinical samples, the expression of Rab1A or DHX33 (show DHX33 Proteins) was reversely correlated with miR (show MLXIP Proteins)-634. Re-expression of Rab1A or DHX33 (show DHX33 Proteins) abrogated the miR (show MLXIP Proteins)-634-mediated inhibition of cell proliferation and migration. Collectively, our data suggest a tumor suppressor role of miR (show MLXIP Proteins)-634 in hepatocellular carcinoma.

  2. New Rab1 binding sites have been discovered using an ensemble of clustering methods.

  3. Leucine-rich repeat kinase 2 (LRRK2 (show LRRK2 Proteins)) can interact with several Rab (show HRB Proteins) proteins, and such ractions may serve to recruit LRRK2 (show LRRK2 Proteins) to distinct subcellular organelles to phosphorylate select substrate proteins involved in membrane trafficking events.

  4. As a Rab1a effector, C9orf72 (show C9ORF72 Proteins) controls initiation of autophagy by regulating the Rab1a-dependent trafficking of the ULK1 (show ULK1 Proteins) autophagy initiation complex to the phagophore.

  5. our data indicate that miR (show MLXIP Proteins)-1202 suppresses proliferation and induces endoplasmic reticulum stress and apoptosis through targeting and inhibiting Rab1A in glioma cells. These results suggest miR (show MLXIP Proteins)-1202 as a potential therapeutic target for the treatment of glioma patients.

  6. Upregulation of RAB1A is associated with triple-negative breast cancer.

  7. For RAB1A, a high accuracy for the discrimination of human hepatocellular carcinoma and nontumorous liver tissue was observed.

  8. The ability of Rab1 to regulate WHAMM and the Arp2/3 complex represents a distinct strategy for membrane remodeling in which a Rab G-protein recruits the actin nucleation machinery but dampens its activity.

  9. Rab1A isoform 3 shows enhanced basal activity and is not controlled by accessory proteins

  10. Results demonstrate that ALS-mutant forms of TDP-43, FUS, and SOD1 all perturb protein transport in the early secretory pathway between ER and Golgi compartments, and imply that restoring Rab1-mediated ER-Golgi transport is a novel ALS therapeutic target

RAB1A Protein Profile

Protein Summary

This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms.

Gene names and symbols associated with RAB1A

  • RAB1A, member RAS oncogene family (rab1a)
  • RAB1A, member RAS oncogene family (RAB1A)
  • RAB1A, member RAS oncogene family (LOC100339709)
  • CG3320 gene product from transcript CG3320-RA (Rab1)
  • rab1A protein (rab1A)
  • PfRab1a (Rab1a)
  • hypothetical protein (Rab1a)
  • Rab GTPase (rab1A)
  • RAB1, member RAS oncogene family (Rab1)
  • RAB1A, member RAS oncogene family (Rab1a)
  • AAF55873 protein
  • Ac2-048 protein
  • CG3320 protein
  • dar6 protein
  • DDBDRAFT_0185730 protein
  • DDBDRAFT_0191476 protein
  • DDB_0185730 protein
  • DDB_0191476 protein
  • Dmel\\CG3320 protein
  • DmRab1 protein
  • Dm Rab1 protein
  • drab1 protein
  • fb53a02 protein
  • Gtbp protein
  • MGC53138 protein
  • mKIAA3012 protein
  • oncogene protein
  • Rab-1 protein
  • Rab1 protein
  • Rab1A protein
  • RAB1B protein
  • Rab1r protein
  • RAS protein
  • si:zc101n13.3 protein
  • wu:fb53a02 protein
  • YPT1 protein

Protein level used designations for RAB1A

ras-related protein Rab-1A , RAB1A, member RAS oncogene family , RAB1, member RAS oncogene family , Rab-protein 1 , CG3320-PA , Rab1-PA , dendritic arbor reduction 6 , rab1A protein , PfRab1a , hypothetical protein , YPT1-related protein , ras-related YPT1 protein , GTP binding protein Rab1a , Rab GTPase YPT1 homolog , RAB1B, member RAS oncogene family

GENE ID SPECIES
368883 Danio rerio
379830 Xenopus laevis
448007 Xenopus (Silurana) tropicalis
459280 Pan troglodytes
696962 Macaca mulatta
100196294 Salmo salar
100339709 Oryctolagus cuniculus
42524 Drosophila melanogaster
553886 Lotus japonicus
812953 Plasmodium falciparum 3D7
7195044 Phaeodactylum tricornutum CCAP 1055/1
8624312 Dictyostelium discoideum AX4
19324 Mus musculus
5861 Homo sapiens
403774 Canis lupus familiaris
81754 Rattus norvegicus
595116 Sus scrofa
421273 Gallus gallus
101087312 Felis catus
539339 Bos taurus
100860796 Capra hircus
100302065 Ovis aries
100719957 Cavia porcellus
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