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The protein encoded by RAB23 belongs to the small GTPase superfamily, Rab family. Additionally we are shipping RAB23 Antibodies (72) and RAB23 Proteins (8) and many more products for this protein.
this study showed that Rab23 regulates Nodal signaling in left- right patterning of th emouse and zebrafish.
Our findings have uncovered a hitherto unknown effector of Rab23 and demonstrate how Rab23 could mediate the transport of Kif17 to the primary cilium
D1-type dopaminergic receptors are delivered to cilia by a mechanism requiring the receptor cytoplasmic tail, the intraflagellar transport complex-B (IFT-B), and ciliary kinesin KIF17. This targeting mechanism critically depends on Rab23.
Rab23 regulates subcellular localization of essential components of the Hedgehog (show SHH ELISA Kits) pathway that act downstream of Smoothened and upstream of Gli (show GLI1 ELISA Kits) proteins.
Expression of Rab23 in the adult brain is suggestive, however, of having a postnatal function beyond its role in embryonic development.
Rab23 functions downstream of Smo and affects the function of the Shh (show SHH ELISA Kits)-regulated Gli (show GLI1 ELISA Kits) family of transcription factors
Rab23 is involved in the control of Sox9 (show SOX9 ELISA Kits) expression via Gli1 (show GLI1 ELISA Kits) protein
Rab23 serves as an important oncoprotein in human astrocytoma by regulating cell invasion and migration through Rac1 activity
High Rab23 expression is associated with bladder cancer.
Forced expression of MiR (show MLXIP ELISA Kits)-92b decreased the mRNA and protein level of RAB23, and RAB23 rescued the biological functions of miR (show MLXIP ELISA Kits)-92b. Taken together, this study revealed the oncogenic roles and the regulation of RAB23 in esophageal squamous cell carcinoma, suggesting RAB23 might be a therapeutic target
Rab23 enhance squamous cell carcinoma cell invasion via up-regulating Rac1.
Rab23 is expressed in breast cancer cells, and ectopic expression of Rab23 inhibits the growth and proliferation as well as induces cell apoptosis in breast cancer cells These effects may be due to the inhibition by Rab23 of Gli1 (show GLI1 ELISA Kits) and Gli2 (show GLI2 ELISA Kits) mRNA expression
Data indicate the essential role of GTP binding protein RAB 23 (Rab23) in pancreatic ductal adenocarcinoma (PDAC) inva-sion, motility and metastasis.
Rab23 was a target gene of miR (show MLXIP ELISA Kits)-367, and ectopic expression of Rab23 could reverse the invasion and migration inhibitory activity of miR (show MLXIP ELISA Kits)-367.
The inhibition of the Rab23 cycle decreases the expression and nuclear localization of Gli1 (show GLI1 ELISA Kits).
Rab23 expression level was the highest in Bcap-37 (show PHB2 ELISA Kits) cells.
Rab9A (show RAB9A ELISA Kits) and Rab23 GTPases play crucial roles in autophagy of Group A Streptococcus.
The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It may be involved in small GTPase mediated signal transduction and intracellular protein transportation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
RAB23, member RAS oncogene family
, Ras-related protein Rab-23
, ras-related protein Rab-23
, open brain 2
, protein open brain
, RAB family small GTP binding protein RAB 23