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RAB27A, Member RAS Oncogene Family (RAB27A) ELISA Kits

The protein encoded by RAB27A belongs to the small GTPase superfamily, Rab family. Additionally we are shipping RAB27A Antibodies (67) and RAB27A Proteins (17) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
RAB27A 5873 P51159
Anti-Mouse RAB27A RAB27A 11891 Q9ERI2
Anti-Rat RAB27A RAB27A 50645 P23640
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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 7.81 pg/ml 31.25-2000 pg/mL 96 Tests Log in to see 11 to 13 Days

More ELISA Kits for RAB27A Interaction Partners

Human RAB27A, Member RAS Oncogene Family (RAB27A) interaction partners

  1. We report two unrelated teenagers with hemophagocytic lymphohistiocytosis and an identical heterozygous RAB27A mutation (c.259G-->C).

  2. Data suggest that microRNA miR (show MLXIP ELISA Kits)-582-5p may function as a tumor suppressor in the development of colorectal carcinoma (CRC (show CALR ELISA Kits)) by targeting RAS-related GTP-binding protein (show RAB10 ELISA Kits) (Rab27a), indicating a novel therapeutic strategy for patients with CRC (show CALR ELISA Kits).

  3. Experimental data are reviewed with a focus on the secretory Rab27 family of small GTPases and their implications in cancer progression.

  4. miR (show MLXIP ELISA Kits)-122 has a Rab27a-dependent function in the hepatitis C virus lifecycle

  5. Rab27A may be used as a valuable prognostic biomarker for colorectal carcinoma patients.

  6. Our data indicate that RAB27A expression is an independent prognostic marker for pancreatic ductal adenocarcinoma

  7. This study identified a common variant located in RAB27A gene influencing FeNO levels specifically in adults and with a biological relevance to the regulation of FeNO levels.

  8. These studies highlight the need for RAB27A sequencing in patients with FHL (show FHL1 ELISA Kits) with normal pigmentation and identify a critical binding site for Munc13-4 (show UNC13D ELISA Kits) on Rab27a, revealing the molecular basis of this interaction.

  9. Data show that cystic fibrosis (show S100A8 ELISA Kits) (CF) neutrophils release less secondary and tertiary granule components and that activation of the low-molecular-mass GTP-binding protein Rab27a, involved in the regulation of granule trafficking, is defective.

  10. Rab27a was identified as a prognostic biomaker by mRNA profiling, correlated with malignant progression and subtype preference in gliomas.

Mouse (Murine) RAB27A, Member RAS Oncogene Family (RAB27A) interaction partners

  1. This paper showed an inhibitory effect of Rab27a directly at the pore forming CaV1.3 (show CACNA1D ELISA Kits) subunit of L-type channels, leading to decreased current density and reduced VEGF-A (show VEGFA ELISA Kits) secretion by the retinal pigment epithelium.

  2. results show that Rab27A is present in mouse pancreatic acinar cells and mainly regulates secretion through the minor-regulated pathway

  3. Rab27A deficiency shows the increased surface level of c-fms (show CSF1R ELISA Kits), and the delayed downregulation of RANK in ashen cells, resulting in enhanced signaling of M-CSF (show CSF1R ELISA Kits) and RANKL (show TNFSF11 ELISA Kits).

  4. Rab27b (show RAB27B ELISA Kits) is expressed in bone marrow derived neutrophils and Rab27b (show RAB27B ELISA Kits) knockout (Rab27b (show RAB27B ELISA Kits) KO) along with Rab27a/b double knockout (Rab27DKO) neutrophils exhibit impaired transwell migration in vitro in response to chemokines MIP-2 (show CXCL2 ELISA Kits) and LTB4 (show PTGR1 ELISA Kits).

  5. Our findings indicate that Slp2-a (show SYTL2 ELISA Kits) controls renal cell size through regulation of Rap (show LRPAP1 ELISA Kits)-ezrin (show EZR ELISA Kits) signaling independently of Rab27.

  6. The results showed that Rab27A(Q78L) is unable to localize on mature melanosomes and that its inhibitory activity on melanosome transport is completely dependent on its binding to the Rab27A effector Slac2-a/melanophilin (show MLPH ELISA Kits).

  7. Rab27a has a key role in eosinophil degranulation. Furthermore, these findings have implications for Rab27a-dependent eosinophil degranulation in airway inflammation.

  8. Upregulation of the Rab27a-dependent lysosomal trafficking and secretory pathways contributes to the correction of some of the cellular defects induced by lysosomal overload in cystinosis, including endoplasmic reticulum stress.

  9. Data suggest that Rab27a and Rab27b (show RAB27B ELISA Kits) regulate distinct steps in the bone marrow-derived mast cells (BMMC) degranulation pathway, with Rab27a/Mlph (show MLPH ELISA Kits)/MyoVa (show MYO5A ELISA Kits) regulating cortical actin stability upstream of Rab27a/b/Munc13-4 (show UNC13D ELISA Kits)-dependent granule exocytosis.

  10. Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1 (show PRF1 ELISA Kits), RAB27A, and STX11 (show STX11 ELISA Kits).

RAB27A Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Gene names and symbols associated with RAB27A

  • RAB27A, member RAS oncogene family (rab27a) antibody
  • RAB27A, member RAS oncogene family (RAB27A) antibody
  • RAB27A, member RAS oncogene family (rab27a-b) antibody
  • RAB27A, member RAS oncogene family (Rab27a) antibody
  • 2210402C08Rik antibody
  • 2410003M20Rik antibody
  • 4933437C11Rik antibody
  • ash antibody
  • GS2 antibody
  • HsT18676 antibody
  • MGC80943 antibody
  • MGC89827 antibody
  • RAB27 antibody
  • RAB27A antibody
  • RAM antibody
  • zgc:114135 antibody

Protein level used designations for RAB27A

RAB27A, member RAS oncogene family , Ras-related protein Rab-27A , rab27a, member ras oncogene family , ras-related protein Rab-27A , GTP-binding protein Ram , rab-27 , member RAS oncogene family, RAB27A , ashen , low Mr GTP-binding protein , ram p25 , RAS oncogene family member

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