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anti-RAB27B, Member RAS Oncogene Family (RAB27B) Antibodies

Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking (Chen et al., 1997 [PubMed 9066979]).[supplied by OMIM, Nov 2010].. Additionally we are shipping RAB27B Proteins (13) and RAB27B Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RAB27B 5874 O00194
RAB27B 80718 Q99P58
RAB27B 84590 Q99P74
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Top anti-RAB27B Antibodies at antibodies-online.com

Showing 10 out of 60 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB RAB27B Antibody (Center) (ABIN656670) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin fixed and paraffin embedded human stomach tissue reacted with RAB27B Antibody  followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of RAB27B Antibody  in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the RAB27B antibody detected the RAB27B protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of RAB27B Antibody (C-term) (ABIN651177) in NCI-H460 cell line lysates (35 µg/lane). RAB27B (arrow) was detected using the purified polyclonal antibody. RAB27B Antibody (C-term) (ABIN651177) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Rab27b Antibody Titration: 0.5 ug/mlPositive Control: human testis, mouse liver, brain and testis 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$1,277.83
Details
Mouse Goat Un-conjugated IF   300 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB Western Blot showing Rab27b antibody used at a concentration of 1.0 ug/ml against Mouse Heart Lysate 50 μg Log in to see 7 to 9 Days
$473.93
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

RAB27B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Rat (Rattus)
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Top referenced anti-RAB27B Antibodies

  1. Human Polyclonal RAB27B Primary Antibody for EIA, IHC (p) - ABIN954410 : Hayasaka, Terada, Suzuki, Murakawa, Tachibana, Sankai, Murakami, Yaegashi, Okamura: Intramanchette transport during primate spermiogenesis: expression of dynein, myosin Va, motor recruiter myosin Va, VIIa-Rab27a/b interacting protein, and Rab27b in the manchette during human and monkey spermiogenesis. in Asian journal of andrology 2008 (PubMed)
    Show all 4 references for ABIN954410

  2. Human Polyclonal RAB27B Primary Antibody for IHC (p), WB - ABIN656670 : Hendrix, Maynard, Pauwels, Braems, Denys, Van den Broecke, Lambert, Van Belle, Cocquyt, Gespach, Bracke, Seabra, Gahl, De Wever, Westbroek: Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis. in Journal of the National Cancer Institute 2010 (PubMed)
    Show all 2 references for ABIN656670

  3. Human Polyclonal RAB27B Primary Antibody for FACS, WB - ABIN651177 : Tiwari, Italiano, Barral, Mules, Novak, Swank, Seabra, Shivdasani: A role for Rab27b in NF-E2-dependent pathways of platelet formation. in Blood 2003 (PubMed)

More Antibodies against RAB27B Interaction Partners

Rabbit RAB27B, Member RAS Oncogene Family (RAB27B) interaction partners

  1. Rab27b enrichment occurs early in secretory vesicle formation.

  2. Rab27b participates in aspects of lacrimal gland acinar cell secretory vesicle formation and release.

  3. Rab27b is associated with tubulovesicle membranes in the parietal cell and Rab27b may play a role in stimulation-associated membrane recruitment and gastric acid secretion.

Human RAB27B, Member RAS Oncogene Family (RAB27B) interaction partners

  1. decreased expression of Rab27A (show RAB27A Antibodies) and Rab27B, especially Rab27A (show RAB27A Antibodies), closely correlated with tumor progression and are valuable prognostic indicators in colorectal cancer patients.

  2. Data indicate that a significant correlation between rab (show HRB Antibodies) GTP-binding protein (RAB27B) and p53 tumor suppressor protein (p53 (show TP53 Antibodies)) expression was observed.

  3. MiR (show MLXIP Antibodies)-193a-3p and miR (show MLXIP Antibodies)-193a-5p play important roles in osteosarcoma metastasis through down-regulation of the Rab27B and SRR (show SRR Antibodies) genes and therefore may serve as useful biomarkers for the diagnosis of osteosarcoma

  4. These data indicate that Rab27B is involved at a different steps of zymogen granule maturation and secretion, which is distinct from that of Rab3D (show RAB3D Antibodies).

  5. Experimental data are reviewed with a focus on the secretory Rab27 (show RAB27A Antibodies) family of small GTPases and their implications in cancer progression.

  6. Decreased invasion partly resulted from reduced expression and activation of MMP-9 (show MMP9 Antibodies) after Rab27b knockdown. Downregulation of Rab27b also suppressed tumor growth in vivo.

  7. Data indicate that the secretion of microRNA miR (show MLXIP Antibodies)-143, depends on rab (show HRB Antibodies) GTP-binding (show RND2 Antibodies) proteins Rab7a (show RAB7A Antibodies) and Rab27b.

  8. Rab27B nuclear expression is correlated with several clinicopathological features of GIST patients, and it may serve as an unfavorable prognostic marker.

  9. Silencing of the exocytotic RAB (show HRB Antibodies) family members RAB27A (show RAB27A Antibodies) or RAB27B halted miR23b and miR921 secretion and reduced cellular invasion.

  10. inhibiting V-ATPase (show ATP6V1H Antibodies) activity by interfering agents and drugs might be an effective strategy for blocking Rab27B-dependent proinvasive secretory vesicle trafficking in ERalpha (show ESR1 Antibodies)-positive breast cancer patients

Mouse (Murine) RAB27B, Member RAS Oncogene Family (RAB27B) interaction partners

  1. Rab27b is expressed in bone marrow derived neutrophils and Rab27b knockout (Rab27b KO) along with Rab27a/b (show RAB27A Antibodies) double knockout (Rab27DKO) neutrophils exhibit impaired transwell migration in vitro in response to chemokines MIP-2 (show CXCL2 Antibodies) and LTB4 (show PTGR1 Antibodies).

  2. EPI64B (show TBC1D10B Antibodies) can serve as a potential physiological GAP for Rab27B and thereby participate in the regulation of exocytosis in pancreatic acinar cells.

  3. Expression of Rab27b DN constructs resulted in dispersed collagen vesicles which may represent failed secretory vesicles sequestered in the cytosol.

  4. Data suggest that Rab27a (show RAB27A Antibodies) and Rab27b regulate distinct steps in the bone marrow-derived mast cells (BMMC) degranulation pathway, with Rab27a (show RAB27A Antibodies)/Mlph (show MLPH Antibodies)/MyoVa (show MYO5A Antibodies) regulating cortical actin stability upstream of Rab27a/b (show RAB27A Antibodies)/Munc13-4 (show UNC13D Antibodies)-dependent granule exocytosis.

  5. Data indicate that inhibition of Rab27a (show RAB27A Antibodies), but not Rab27b, affects exosome secretion.

  6. Rab27b participates in aspects of lacrimal gland acinar cell secretory vesicle formation and release.

  7. Stimulation-dependent lysosomal RANKL (show TNFSF11 Antibodies) release is mediated by Rab27a/b (show RAB27A Antibodies) and their effector molecules, and this mechanism may be important for osteoclast activation in vivo.

  8. Morphological changes observed at the ultrastructural level in Rab27b-deficient lung samples result from secretory defects in alveolar epithelial type II and Clara cells that, over time, lead to atrophy of the epithelium.

  9. Both Rab27a (show RAB27A Antibodies) and Rab27b deficiencies impaired azurophilic granule exocytosis. Rab27a (show RAB27A Antibodies)(ash/ash) neutrophils showed upregulation of Rab27b expression which did not compensate for the secretory defects observed in Rab27a (show RAB27A Antibodies)-deficient cells.

  10. Chromosomal mapping and gene structure of the RAB27B gene.

Cow (Bovine) RAB27B, Member RAS Oncogene Family (RAB27B) interaction partners

RAB27B Antigen Profile

Protein Summary

Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking (Chen et al., 1997

Gene names and symbols associated with RAB27B

  • RAB27B, member RAS oncogene family (rab27b) antibody
  • RAB27B, member RAS oncogene family (RAB27B) antibody
  • RAB27B, member RAS oncogene family (LOC100343056) antibody
  • RAB27b, member RAS oncogene family (Rab27b) antibody
  • RAB27B, member RAS oncogene family (Rab27b) antibody
  • 2310021G14Rik antibody
  • B130064M09Rik antibody
  • C25KG antibody
  • MGC79588 antibody
  • MGC80016 antibody
  • RAB27B antibody

Protein level used designations for RAB27B

RAB27B, member RAS oncogene family , ras-related protein Rab-27B

GENE ID SPECIES
414551 Xenopus laevis
448182 Xenopus (Silurana) tropicalis
468542 Pan troglodytes
694445 Macaca mulatta
100343056 Oryctolagus cuniculus
5874 Homo sapiens
80718 Mus musculus
84590 Rattus norvegicus
282858 Bos taurus
483974 Canis lupus familiaris
101096852 Felis catus
101120036 Ovis aries
100732593 Cavia porcellus
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