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The protein encoded by RAB2A belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. Additionally we are shipping RAB2A, Member RAS Oncogene Family Antibodies (79) and RAB2A, Member RAS Oncogene Family Proteins (19) and many more products for this protein.
Identify Rab2 as a key factor for autophagic and endocytic cargo delivery to and degradation in lysosomes.
our data reveal that RAB2A is new critical membrane trafficking players in the regulation of mesenchymal properties of normal and tumorigenic cells and a critical determinant of an invasive, proteolytic mode of BC progression.
RAB2A variance has effect on the structure and function of the PFC (show CFP ELISA Kits) and related cognitive functions.
This study demonstrated that RAB2A mutation showing the highest statistical significance in Autism and Schizophrenia.
The immunohistochemistry-based validation using tissue microarray slides in oral squamous cell carcinoma revealed overexpression of the RAB2A and PRDX1 (show PRDX1 ELISA Kits) gene in 80 and 68 % of the tested clinical cases, respectively.
Pin1 (show PIN1 ELISA Kits)/Rab2A/Erk (show EPHB2 ELISA Kits) drives BCSC expansion and tumorigenicity, suggesting potential drug targets.
As a result of the translocations, RAB2A-PLAG1 (show PLAG1 ELISA Kits), the constitutively active promoter of the partner gene drives the ectopic expression of PLAG1 (show PLAG1 ELISA Kits).
first X-ray crystal structure of RicA to 2.7 A resolution and have quantified the affinity of RicA binding to human Rab2 in its GDP-bound and nucleotide-free forms
The authors identified a specific interaction between the human small GTPase Rab2 and a Brucella spp. protein named RicA.
The results of this study provided that RAB2A and SLC38A1 (show SLC38A1 ELISA Kits), were associated with the density of calbindin (show CALB1 ELISA Kits)-positive neurons and the number of perineuronal oligodendrocytes in psychiatric disorders.
An unprecedented direction of RAB2A-mediated vesicular transport in spermatids during acrosomal biogenesis, from the trans-side of the Golgi apparatus to the nuclear envelope.
These results suggest that the dual effector, Noc2 (show RPH3AL ELISA Kits), regulates the transition from Rab2a-mediated granule biogenesis to Rab27a (show RAB27A ELISA Kits)-mediated granule exocytosis.
Symbiotic bacteria directed selective cargo sorting in Paneth cells to promote symbiosis through Nod2 (show NOD2 ELISA Kits) and LRRK2 (show LRRK2 ELISA Kits). Deficiency of Nod2 (show NOD2 ELISA Kits), LRRK2 (show LRRK2 ELISA Kits) or Rab2a or depletion of commensals resulted in lysosomal degradation of lysozyme (show LYZ ELISA Kits).
Rab2A is a pivotal switch protein that promotes either secretion or endoplasmic reticulum-associated degradation of (pro)insulin (show INS ELISA Kits) in insulin (show INS ELISA Kits)-secreting cells.
CSFV proliferation was promoted by GBF1 (show GBF1 ELISA Kits) and Rab2 overexpression using a lentiviral system. Hence, Golgi function is important for CSFV multiplication, and GBF1 (show GBF1 ELISA Kits) and Rab2 participate in CSFV proliferation.
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
RAB2, member RAS oncogene family
, ras-related protein Rab-2A
, RAB2A, member RAS oncogene family
, GTP-binding protein
, small GTP binding protein RAB2A
, GTP-binding protein (rab2)
, tubulovesicle-membrane-associated GTP-binding protein