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Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting (Bao et al., 2002 [PubMed 11784320]).[supplied by OMIM, Jul 2009].. Additionally we are shipping RAB31 Antibodies (34) and RAB31 Proteins (9) and many more products for this protein.
this study provides the evidence of Rab31 overexpression in HCC (show FAM126A ELISA Kits), and Rab31 is potentially used as a novel biomarker of poor prognosis in patients with HCC (show FAM126A ELISA Kits). PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits)/Bcl-2 (show BCL2 ELISA Kits)/BAX (show BAX ELISA Kits) axis was involved in Rab31-promoting HCC (show FAM126A ELISA Kits) progression.
Data indicate that early endosome antigen 1 (EEA1 (show EEA1 ELISA Kits)) is important for the small GTPase (show RACGAP1 ELISA Kits) Rab31-mediated enhancement of ligand-bound EGF receptor (EGFR (show EGFR ELISA Kits)) endocytic trafficking.
MUC1 (show MUC1 ELISA Kits)-C and Rab31 function in an autoinductive loop that contributes to overexpression of MUC1 (show MUC1 ELISA Kits)-C in breast cancer cells.
Overexpression of rab31 in breast cancer cells leads to a switch from an invasive to a proliferative phenotype as indicated by an increased cell proliferation, reduced adhesion and invasion in vitro, and a reduced capacity to form lung metastases in vivo.
Neither UPARwt, nor UPAR (show PLAUR ELISA Kits)-del4/5 nor RAB31 mRNA expression levels were found to be prognostic markers in advanced ovarian cancer.
RIN3 (show RIN3 ELISA Kits) specifically acts as a GEF for Rab31.
Thus, Rab22B may have a role in anterograde exit from the trans-Golgi network .
uPAR (show PLAUR ELISA Kits)-del4/5 and rab31 mRNA represent independent prognostic markers in breast cancer and may be components of different, but possibly associated, tumor-relevant signaling pathways.
Rab22B possibly plays role in regulating e (show NES ELISA Kits)pidermal growth factor receptor (EGFR) and mannose 6-phosphate receptor (M6PR) transport into late endosomes.
Rab31, with APPL2 (show APPL2 ELISA Kits) as its effector, play a role in FcgammaR-mediated phagocytosis through PI3K/Akt (show AKT1 ELISA Kits) signaling in macrophages.
a previously unrecognised role for Rab31 in influencing the differentiation and fate of neural progenitor cells
Insulin (show INS ELISA Kits) recruits the CIP4 (show TRIP10 ELISA Kits)/Gapex-5 (show GAPVD1 ELISA Kits) complex to the plasma membrane, thus reducing Rab31 activity and permitting Glut4 (show SLC2A4 ELISA Kits) vesicles to translocate to the cell surface, where Glut4 (show SLC2A4 ELISA Kits) docks and fuses to transport glucose into the cell.
Rab22B is exceptionally enriched in nestin (show NES ELISA Kits) and RC2-positive radial glia of the embryonic mouse brain. In the adult brain, Rab22B is rather specifically expressed in glial fibrillary acidic protein (GFAP (show GFAP ELISA Kits))-positive mature astrocytes.
Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting (Bao et al., 2002
RAB31, member RAS oncogene family
, ras-related protein Rab-31
, ras-related protein Rab-22B
, GTP-binding protein Rab0
, monomeric GTP-binding protein