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Small GTP-binding proteins of the RAB family, such as RAB33B, play important roles at defined steps of vesicular transport in protein secretion and the endocytosis pathway (Zheng et al., 1998 [PubMed 9512502]).[supplied by OMIM, Feb 2010].. Additionally we are shipping RAB33B Antibodies (17) and RAB33B Proteins (6) and many more products for this protein.
Rab33 modulates autophagosome formation through interaction with Atg16L (show ATG16L1 ELISA Kits)
Here we present three SMC (show DYM ELISA Kits) patients with four novel pathogenic variants in RAB33B, including homozygosity for c.211C>T (p.R71*), homozygosity for c.365T>C (p.F122S), and compound heterozygosity for c.48delCGGGGCAG (p.G17Vfs*58) and c.490C>T (p.Q164*).
Arg-24 of Atg16L1 (show ATG16L1 ELISA Kits) is crucial for its interaction with Atg5 (show ATG5 ELISA Kits) which has implications in the binding of the dimeric complex to Rab33B
Analysis of hepatitis B virus capsid maturation steps revealed that Rab33B and Atg5/12/16L1 are required for proper particle assembly and/or stability.
Ric1-Rgp1 complex is a guanine nucleotide exchange factor (show RASGRF1 ELISA Kits) for the late Golgi Rab6A (show RAB6A ELISA Kits) GTPase (show RACGAP1 ELISA Kits) and an effector of the medial Golgi Rab33B GTPase (show RACGAP1 ELISA Kits).
A second autosomal recessive locus for Dyggve-Melchior-Clausen syndrome exists on 4q31.1 and that Rab (show HRB ELISA Kits) protein-encoding gene, RAB33B, is the likely disease gene in that locus.
Small GTP-binding proteins of the RAB family, such as RAB33B, play important roles at defined steps of vesicular transport in protein secretion and the endocytosis pathway (Zheng et al., 1998
RAB33B, member RAS oncogene family
, ras-related protein Rab-33B
, RAB33B, member of RAS oncogene family