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May be involved in melanosomal transport and docking. Additionally we are shipping RAB38, Member RAS Oncogene Family Proteins (5) and many more products for this protein.
Showing 10 out of 55 products:
Human Monoclonal RAB38 Primary Antibody for ELISA, WB - ABIN565150
Mueller, Rehli, Bosserhoff: miRNA expression profiling in melanocytes and melanoma cell lines reveals miRNAs associated with formation and progression of malignant melanoma. in The Journal of investigative dermatology 2009
Data suggest RUTBC1/SGSM2 in melanocytes functions as physiological GTPase-activating protein for Rab32/Rab38 in regulation of transport of melanogenic enzymes (tyrosinase, tyrosinase-related protein 1, dopachrome isomerase) into melanosomes.
RHOC (show RHOC Antibodies) and RAB38 are dispensable for osteoclast function.
Loss of functional Rab38 in the "chocolate" (cht (show ChT Antibodies)) mouse causes dramatically reduced numbers of melanosomes in adult retinal pigment epithelium, in contrast to the mild phenotype previously shown in skin melanocytes.
Rab38(cht/cht) mice show ocular characteristics reminiscent of human oculocutaneous albinism, as well as iris and RPE (show RPE Antibodies) thinning.
These results suggest that the genetic abnormality of Rab38 affects multiple lysosome-related organelles, resulting in lung disease in addition to oculocutaneous albinism.
Varp (show ANKRD27 Antibodies) functions as the Rab32 (show RAB32 Antibodies)/38 effector that controls trafficking of Tyrp1 (show TYRP1 Antibodies) in melanocytes.
Rab38 was associated with albuminuria in type 2 diabetes patients. Relative expression of RAB38 was higher in tubuli of patients with diabetic kidney disease compared with control subjects.
Rab38 and its close homolog Rab32 bind to Myosin Vc but not to Myosin Va or Myosin Vb. Binding depends on residues in the switch II region of Rab32 and Rab38 and regions of the Myosin Vc coiled-coil tail domain.
MiR (show MLXIP Antibodies)-124 significantly decreases the H2O2-induced apoptosis of human hepatic L02 cells by targeting the Rab38 gene and activating the AKT (show AKT1 Antibodies) pathway.
The expression levels of RAB38 were significantly associated with grade progression as well as prognosis in gliomas. RAB38 is an important prognostic biomarker and potential therapeutic target in gliomas.
BLOC-3 is a Rab32 (show RAB32 Antibodies) and Rab38 guanine nucleotide exchange factor (show RASGRF1 Antibodies), with a specific function in the biogenesis of lysosome-related organelles.
that Rab38 and Rab32 (show RAB32 Antibodies) are the specific factors that direct the ubiquitous machinery to mediate transport from early endosomes to maturing LROs.
Studies confirmed elevated expression of three target antigens RAB38, TBCE, and DUSP12 in CML.
Varp (show ANKRD27 Antibodies) physically interacts with Rab38, and preferentially binds to the active GTP (show AK3 Antibodies)-bound form of Rab38 both in vitro and in vivo.
May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1.
RAB38, member RAS oncogene family
, ras-related protein Rab-38
, Rab-related GTP-binding protein
, melanoma antigen NY-MEL-1
, Rab38, member of RAS oncogene family
, red eyed dilution
, ruby or red eyed dilution
, small GTP binding protein