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Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Additionally we are shipping RAB3A, Member RAS Oncogene Family Proteins (10) and many more products for this protein.
Showing 10 out of 103 products:
Cow (Bovine) Polyclonal RAB3A Primary Antibody for ICC, IP - ABIN1742211
Vasileva, Horstmann, Geumann, Gitler, Kuner: Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission. in The European journal of neuroscience 2012
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Human Polyclonal RAB3A Primary Antibody for WB - ABIN658735
Szodorai, Kuan, Hunzelmann, Engel, Sakane, Sasaki, Takai, Kirsch, Müller, Beyreuther, Brady, Morfini, Kins: APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
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Human Polyclonal RAB3A Primary Antibody for EIA, WB - ABIN954411
Branham, Bustos, De Blas, Rehmann, Zarelli, Treviño, Darszon, Mayorga, Tomes: Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis. in The Journal of biological chemistry 2009
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Human Polyclonal RAB3A Primary Antibody for WB - ABIN372708
Schlüter, Schmitz, Jahn, Rosenmund, Südhof: A complete genetic analysis of neuronal Rab3 function. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2004
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Dog (Canine) Monoclonal RAB3A Primary Antibody for IF, IP - ABIN967929
Novick, Brennwald: Friends and family: the role of the Rab GTPases in vesicular traffic. in Cell 1993
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Human Polyclonal RAB3A Primary Antibody for ICC, IHC - ABIN1742210
Spangler, Schmitz, Kevenaar, de Graaff, de Wit, Demmers, Toonen, Hoogenraad: Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission. in The Journal of cell biology 2013
Cow (Bovine) Polyclonal RAB3A Primary Antibody for WB - ABIN2792282
Zahraoui, Touchot, Chardin, Tavitian: The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion. in The Journal of biological chemistry 1989
Rab3a accelerates cell proliferation by increasing cyclin D1 (show CCND1 Antibodies) expression, enhances anti-cancer drug resistance, and increases tumorigenicity and self-renewal of glioma cells.
Data indicate that exocytic stimuli promote ADP ribosylation factor 6 (ARF6 (show ARF6 Antibodies)) activation, which accomplishes exocytosis by stimulating Rab3A GTP-Binding Protein.
Five compounds which possess good inhibitory activity and may act as potential high affinity inhibitors against Rab3A active site were identified
alpha-Synuclein (show SNCA Antibodies) membrane association is regulated by the Rab3a recycling machinery and presynaptic activity
Rab27 (show RAB27A Antibodies) and Rab3 sequentially regulate human sperm dense-core granule exocytosis.
Myo5a (show MYO5A Antibodies) and Rab3A are direct binding partners and interact on synaptic vesicles and the Myo5a (show MYO5A Antibodies)/Rab3A complex is involved in transport of neuronal vesicles
Mutation screening of the RAB3A gene in 47 individuals with autism provided no evidence that DNA variants in this gene are associated with autism.
Cholesterol content regulates acrosomal exocytosis by enhancing Rab3A plasma membrane association.
In conclusion, we have found no evidence for RAB3A conferring susceptibility on mental retardation in the Han Chinese population.
Initiates exocytosis in acrosome when prenylated and activated with guanosine triphosphate (GTP (show AK3 Antibodies)).
Rab3a deficiency promotes constitutive secretion and underlies selective impairment of Ca(2 (show CA2 Antibodies))-dependent release of alpha-MSH
Rab3a deletion restores excitatory/inhibitory imbalance in synapsin II (show SYN2 Antibodies)(-) hippocampal slices.
betaARs couple to a cAMP/Epac (show RAPGEF3 Antibodies)/PLC (show HSPG2 Antibodies)/Munc13-1 (show UNC13A Antibodies)/Rab3a/RIM1a (show RIMS1 Antibodies)-dependent pathway to enhance glutamate (show GRIN1 Antibodies) release at cerebrocortical nerve terminals.
key role of Rab3a proteins control the balance between secretory vesicle biogenesis and degradation, and suggest that the ablation of this protein probably changes the nature of the reservoir of secretory vesicles available for regulated exocytosis.
Data show diminished actin plasticity in the cell processes of Rab3A knockout (KO) podocytes.
these findings suggest a crucial role of Rab3A in delivering vesicles to Ca2 (show CA2 Antibodies)+ -dependent release sites at ribbon synapses.
We conclude that Rab3A is involved in a novel presynaptic mechanism to homeostatically regulate the amount of transmitter in a quantum.
Rab3A in the GTP (show AK3 Antibodies) bound conformation prevents activity-dependent facilitation of exocytosis in bovine adrenal chromaffin cells
Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
ras-related protein Rab-3C
, RAB3D, member RAS oncogene family
, RAB3A, member RAS oncogene family
, ras-related protein Rab-3A
, RAS-associated protein RAB3A
, Ras-related small GTP binding protein 3A
, SMG P25A