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Required for the fusion of plasma membranes and early endosomes (By similarity).. Additionally we are shipping RAB5 Proteins (22) and RAB5 Kits (13) and many more products for this protein.
Showing 10 out of 205 products:
Cow (Bovine) Polyclonal RAB5 Primary Antibody for ICC, IF - ABIN266020
Sönnichsen, De Renzis, Nielsen, Rietdorf, Zerial: Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11. in The Journal of cell biology 2000
Show all 8 references for ABIN266020
Cow (Bovine) Polyclonal RAB5 Primary Antibody for ICC, IF - ABIN361846
Ali, Wasmeier, Lamoreux, Strom, Seabra: Multiple regions contribute to membrane targeting of Rab GTPases. in Journal of cell science 2004
Show all 7 references for ABIN361846
Human Monoclonal RAB5 Primary Antibody for IF, IP - ABIN967881
Huang, Imamura, Olefsky: Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein. in Proceedings of the National Academy of Sciences of the United States of America 2001
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Dog (Canine) Monoclonal RAB5 Primary Antibody for IF, IHC - ABIN968138
Li, Stahl: Structure-function relationship of the small GTPase rab5. in The Journal of biological chemistry 1993
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Human Monoclonal RAB5 Primary Antibody for EIA, WB - ABIN317558
Yao-Borengasser, Varma, Bodles, Rasouli, Phanavanh, Lee, Starks, Kern, Spencer, Rashidi, McGehee, Fried, Kern: Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone. in The Journal of clinical endocrinology and metabolism 2007
Show all 2 references for ABIN317558
Mouse (Murine) Polyclonal RAB5 Primary Antibody for ICC, IF - ABIN447323
Ramakrishnan, Tyurin, Tuyrin, Veglia, Condamine, Amoscato, Mohammadyani, Johnson, Zhang, Klein-Seetharaman, Celis, Kagan, Gabrilovich: Oxidized lipids block antigen cross-presentation by dendritic cells in cancer. in Journal of immunology (Baltimore, Md. : 1950) 2014
Dog (Canine) Polyclonal RAB5 Primary Antibody for IHC, WB - ABIN2786773
Coyne, Shen, Turner, Bergelson: Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5. in Cell host & microbe 2007
Human Polyclonal RAB5 Primary Antibody for FACS, IF - ABIN390962
Farnsworth, Seabra, Ericsson, Gelb, Glomset: Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A. in Proceedings of the National Academy of Sciences of the United States of America 1995
results suggest a new mechanism in which Rab5 induces a change in flexibility of EEA1 (show EEA1 Antibodies), generating an entropic collapse force that pulls the captured vesicle towards the target membrane to initiate docking and membrane fusion
structural differences may provide an opportunity to selectively target one Rab5 state and lead to new approaches in the development of Rab5-specific therapies
Data show that rab5 GTP-Binding Protein (Rab5a) is overexpressed in human hepatocellular carcinoma (HCC (show FAM126A Antibodies)) and contributes to cancer cell proliferation and invasion through regulation of FAK (show PTK2 Antibodies) and AKT (show AKT1 Antibodies) signaling.
TTBK2 (show TTBK2 Antibodies) down-regulates GluK2 (show GRIK2 Antibodies) activity by decreasing the receptor protein abundance in the cell membrane via RAB5-dependent endocytosis.
Results indicate that persistent rab5 overactivation through beta-cleaved carboxy-terminal fragment of APP (show APP Antibodies)-APPL1 (show APPL1 Antibodies) interactions constitutes a novel APP (show APP Antibodies)-dependent pathogenic pathway in Alzheimer's disease
Results demonstrate that DRG2 (show DRG2 Antibodies) is an endosomal protein and a key regulator of Rab5 deactivation and Tfn (show Tf Antibodies) recycling.
Rab5a is involved in critical events not only at the beginning of the autophagy process with endosomal formation (initiation), but also later on, being important for autophagosome sealing and fusion with lysosomes through an interplay with Beclin 1 (show BECN1 Antibodies).
Findings indicate the role of CMTM7 (show CMTM7 Antibodies) protein in the regulation of epidermal growth factor receptor (EGFR (show EGFR Antibodies))-AKT (show AKT1 Antibodies) proto-oncogene (show RAB1A Antibodies) protein signaling in tumor cells, and as a molecule related to Rab5 GTP-binding protein activation.
Low expression of RAB5A is associated with metastasis in prostate cancer.
PLD1 recovers the decrease in epidermal growth factor receptor (EGFR (show EGFR Antibodies)) endocytosis induced by HIF-1alpha (show HIF1A Antibodies) independent of lipase (show LIPG Antibodies) activity via the Rab5-mediated endosome fusion pathway.
These data highlight a requirement of Rab5 and the endosomal system for the regulation of gluconeogenic gene expression that has important implications for metabolic diseases.
Inpp5e (show INPP5E Antibodies), through functional interactions with Rab20 (show RAB20 Antibodies) on the phagosome, activates Rab5, which, in turn, increases PtdIns3P and delays phagosome acidification.
FGF21 (show FGF21 Antibodies) has a role in promoting endothelial cell angiogenesis through a dynamin-2 (show DNM2 Antibodies) and Rab5 dependent pathway
In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin (show NCDN Antibodies) palmitoylation in its targeting to Rab5-positive endosomes.
In mammalian cells, p110beta acts as a molecular sensor for growth factor availability and induces autophagy by activating a Rab5-mediated signaling cascade.
Data show that Rinl is closely associated with the cytoskeleton and thus contributes to the spatial control of Rab5a and Rab22 signaling at actin-positive compartments.
Data reveal the affinity of Rabex-5 (show RABGEF1 Antibodies)/Rabaptin-5 (show RABEP1 Antibodies)/Rab5-GTP (show AK3 Antibodies) interaction in the cell, which is quantitatively related to the Rabex-5 (show RABGEF1 Antibodies) concentration for the onset of the indirect
Rab5 regulates and coordinates different endocytic mechanisms through its effector Rabankyrin-5 (show ANKFY1 Antibodies)
Using retroviral expression and siRNA Rab5a silencing, data demonstrate that Rab5a is essential for the large endosome phenotype and for localization of mannose receptor.
the recruitment of Gapex-5 (show GAPVD1 Antibodies) to phagosomes through the microtubule network induces transient Rab5 activation
Dominant-negative mutant rab5 inhibits FMDV infection of IBRS-2 cells.
Required for the fusion of plasma membranes and early endosomes (By similarity).
, Rab5a, GTPase
, hypothetical protein
, Ras-related protein Rab-5A
, ras-related protein rab-5a
, RAB5A, member RAS oncogene family
, ras-related protein Rab-5A
, RAS-associated protein RAB5A
, small GTP-binding protein rab5
, GTP-binding protein (rab5)