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RAD1 Homolog (S. Pombe) (RAD1) ELISA Kits

RAD1 encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. Additionally we are shipping RAD1 Antibodies (82) and RAD1 Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat RAD1 RAD1 294800  
Anti-Human RAD1 RAD1 5810 O60671
Anti-Mouse RAD1 RAD1 19355 Q9QWZ1
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More ELISA Kits for RAD1 Interaction Partners

Human RAD1 Homolog (S. Pombe) (RAD1) interaction partners

  1. Intramolecular binding of the rad9 (show RAD9A ELISA Kits) C-terminus in the checkpoint clamp (show PDZK1 ELISA Kits) Rad9 (show RAD9A ELISA Kits)-Hus1 (show HUS1 ELISA Kits)-Rad1 (show ERCC4 ELISA Kits) is closely linked with its DNA binding.

  2. Data show models for the ternary PCNA (show PCNA ELISA Kits)/FEN1 (show FEN1 ELISA Kits)/DNA and Rad9 (show RAD9A ELISA Kits)-Rad1 (show ERCC4 ELISA Kits)-Hus1 (show HUS1 ELISA Kits) (9-1-1 complex)/FEN1 (show FEN1 ELISA Kits)/DNA assemblies.

  3. The RAD1 (show ERCC4 ELISA Kits) is loaded to damaged sites where it serves as a platform for the selective recruitment of checkpoint and repair proteins.

  4. CK2 (show CSNK2A1 ELISA Kits) plays a crucial role in the ATR (show ANTXR1 ELISA Kits)-dependent checkpoint pathway through its ability to phosphorylate Ser (show SIGLEC1 ELISA Kits)-341 and Ser (show SIGLEC1 ELISA Kits)-387 of the Rad9 (show RAD9A ELISA Kits) subunit of the Rad9 (show RAD9A ELISA Kits)-Hus1 (show HUS1 ELISA Kits)-Rad1 (show ERCC4 ELISA Kits) complex

  5. Rad9 (show RAD9A ELISA Kits)-Rad1 (show ERCC4 ELISA Kits)-Hus1 (show HUS1 ELISA Kits) complex enhances in vitro activity of 8-oxoguanine DNA glycosylase (show OGG1 ELISA Kits).

  6. Rad9 (show RAD9A ELISA Kits), Hus1 (show HUS1 ELISA Kits), and Rad1 (show ERCC4 ELISA Kits) heterotrimeric complex chromatin binding is a proximal event in the checkpoint signaling cascade

  7. RAD1 (show ERCC4 ELISA Kits) is a potential intrinsic chaperone in the stabilization of HUS1 (show HUS1 ELISA Kits) for the heterotrimeric (RAD9 (show RAD9A ELISA Kits)-RAD1 (show ERCC4 ELISA Kits)-HUS1 (show HUS1 ELISA Kits)) checkpoint complex formation.

  8. The human Rad9 (show RAD9A ELISA Kits)/Rad1 (show ERCC4 ELISA Kits)/Hus1 (show HUS1 ELISA Kits) complex interacts with and stimulates DNA polymerase beta (show POLB ELISA Kits) activity.

  9. complex with rad9 (show RAD9A ELISA Kits) and hus1 (show HUS1 ELISA Kits) is a damage-specific activator of flap endonuclease 1 (show FEN1 ELISA Kits)

  10. The long-patch base excision machinery is an important target of the Rad9 (show RAD9A ELISA Kits)-Rad1 (show ERCC4 ELISA Kits)-Hus1 (show HUS1 ELISA Kits) complex, thus enhancing the quality control of DNA.

Mouse (Murine) RAD1 Homolog (S. Pombe) (RAD1) interaction partners

  1. HUS1 (show HUS1 ELISA Kits) acts as a component of the canonical 9-1-1 complex during meiotic prophase I to promote DSB repair and further propose that RAD1 and TOPBP1 (show TOPBP1 ELISA Kits) respond to unsynapsed chromatin through an alternative mechanism that does not require RAD9 (show RAD9A ELISA Kits) or HUS1 (show HUS1 ELISA Kits).

  2. The rad1 protein is required for repairing DNA lesions induced by UV-light, HU and gamma rays, and for mediating G(2)/M and S/M checkpoint controls.

  3. data indicate that Rad1(K185) is not a functional counterpart of PCNA (show PCNA ELISA Kits)(K164).

  4. data suggest that Mrad1 is important for preventing tumor development.

RAD1 Antigen Profile

Antigen Summary

This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.

Gene names and symbols associated with RAD1

  • RAD1 homolog (S. pombe) (Rad1) antibody
  • RAD1 homolog (S. pombe) (rad1) antibody
  • RAD1 homolog (S. pombe) (RAD1) antibody
  • RAD1 homolog (rad1) antibody
  • RAD1 homolog (RAD1) antibody
  • DKFZp459H1127 antibody
  • HRAD1 antibody
  • RAD1 antibody
  • REC1 antibody
  • xrad1 antibody
  • zgc:56502 antibody
  • zgc:77779 antibody

Protein level used designations for RAD1

cell cycle checkpoint protein RAD1 , RAD1 homolog (S. pombe) , RAD1 homolog , Cell cycle checkpoint protein RAD1 , cell cycle checkpoint protein rad1 , DNA repair exonuclease REC1 , DNA repair exonuclease rad1 homolog , cell cycle checkpoint protein Hrad1 , checkpoint control protein HRAD1 , exonuclease homolog RAD1 , rad1-like DNA damage checkpoint protein , mRAD1

GENE ID SPECIES
294800 Rattus norvegicus
393872 Danio rerio
427432 Gallus gallus
461928 Pan troglodytes
479366 Canis lupus familiaris
518502 Bos taurus
548799 Xenopus (Silurana) tropicalis
100173217 Pongo abelii
100528686 Ictalurus punctatus
740886 Pan troglodytes
5810 Homo sapiens
19355 Mus musculus
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