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RAD1 Homolog (S. Pombe) Proteins (RAD1)

RAD1 encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. Additionally we are shipping RAD1 Antibodies (82) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat RAD1 RAD1 294800  
RAD1 5810 O60671
RAD1 19355 Q9QWZ1
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Top RAD1 Proteins at antibodies-online.com

Showing 8 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$467.86
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$5,769.50
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated   2 μg Log in to see 6 Days
$168.54
Details

RAD1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced RAD1 Proteins

  1. Human RAD1 Protein expressed in Escherichia coli (E. coli) - ABIN667802 : Liu, Fang, Shao, Lindsey-Boltz, Sancar, Modrich: Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway. in The Journal of biological chemistry 2010 (PubMed)
    Show all 2 references for ABIN667802

More Proteins for RAD1 Homolog (S. Pombe) (RAD1) Interaction Partners

Human RAD1 Homolog (S. Pombe) (RAD1) interaction partners

  1. Intramolecular binding of the rad9 (show RAD9A Proteins) C-terminus in the checkpoint clamp (show PDZK1 Proteins) Rad9 (show RAD9A Proteins)-Hus1 (show HUS1 Proteins)-Rad1 is closely linked with its DNA binding.

  2. Data show models for the ternary PCNA (show PCNA Proteins)/FEN1 (show FEN1 Proteins)/DNA and Rad9 (show RAD9A Proteins)-Rad1-Hus1 (show HUS1 Proteins) (9-1-1 complex)/FEN1 (show FEN1 Proteins)/DNA assemblies.

  3. The RAD1 is loaded to damaged sites where it serves as a platform for the selective recruitment of checkpoint and repair proteins.

  4. CK2 (show CSNK2A1 Proteins) plays a crucial role in the ATR (show ANTXR1 Proteins)-dependent checkpoint pathway through its ability to phosphorylate Ser (show SIGLEC1 Proteins)-341 and Ser (show SIGLEC1 Proteins)-387 of the Rad9 (show RAD9A Proteins) subunit of the Rad9 (show RAD9A Proteins)-Hus1 (show HUS1 Proteins)-Rad1 complex

  5. Rad9 (show RAD9A Proteins)-Rad1-Hus1 (show HUS1 Proteins) complex enhances in vitro activity of 8-oxoguanine DNA glycosylase (show OGG1 Proteins).

  6. Rad9 (show RAD9A Proteins), Hus1 (show HUS1 Proteins), and Rad1 heterotrimeric complex chromatin binding is a proximal event in the checkpoint signaling cascade

  7. RAD1 is a potential intrinsic chaperone in the stabilization of HUS1 (show HUS1 Proteins) for the heterotrimeric (RAD9 (show RAD9A Proteins)-RAD1-HUS1 (show HUS1 Proteins)) checkpoint complex formation.

  8. The human Rad9 (show RAD9A Proteins)/Rad1/Hus1 (show HUS1 Proteins) complex interacts with and stimulates DNA polymerase beta (show POLB Proteins) activity.

  9. complex with rad9 (show RAD9A Proteins) and hus1 (show HUS1 Proteins) is a damage-specific activator of flap endonuclease 1 (show FEN1 Proteins)

  10. The long-patch base excision machinery is an important target of the Rad9 (show RAD9A Proteins)-Rad1-Hus1 (show HUS1 Proteins) complex, thus enhancing the quality control of DNA.

Mouse (Murine) RAD1 Homolog (S. Pombe) (RAD1) interaction partners

  1. HUS1 (show HUS1 Proteins) acts as a component of the canonical 9-1-1 complex during meiotic prophase I to promote DSB repair and further propose that RAD1 and TOPBP1 (show TOPBP1 Proteins) respond to unsynapsed chromatin through an alternative mechanism that does not require RAD9 (show RAD9A Proteins) or HUS1 (show HUS1 Proteins).

  2. The rad1 protein is required for repairing DNA lesions induced by UV-light, HU and gamma rays, and for mediating G(2)/M and S/M checkpoint controls.

  3. data indicate that Rad1(K185) is not a functional counterpart of PCNA (show PCNA Proteins)(K164).

  4. data suggest that Mrad1 is important for preventing tumor development.

RAD1 Protein Profile

Protein Summary

This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.

Gene names and symbols associated with RAD1 Homolog (S. Pombe) Proteins (RAD1)

  • RAD1 homolog (S. pombe) (Rad1)
  • RAD1 homolog (S. pombe) (rad1)
  • RAD1 homolog (S. pombe) (RAD1)
  • RAD1 homolog (rad1)
  • RAD1 homolog (RAD1)
  • DKFZp459H1127 protein
  • HRAD1 protein
  • RAD1 protein
  • REC1 protein
  • xrad1 protein
  • zgc:56502 protein
  • zgc:77779 protein

Protein level used designations for RAD1 Homolog (S. Pombe) Proteins (RAD1)

cell cycle checkpoint protein RAD1 , RAD1 homolog (S. pombe) , RAD1 homolog , Cell cycle checkpoint protein RAD1 , cell cycle checkpoint protein rad1 , DNA repair exonuclease REC1 , DNA repair exonuclease rad1 homolog , cell cycle checkpoint protein Hrad1 , checkpoint control protein HRAD1 , exonuclease homolog RAD1 , rad1-like DNA damage checkpoint protein , mRAD1

GENE ID SPECIES
294800 Rattus norvegicus
393872 Danio rerio
427432 Gallus gallus
461928 Pan troglodytes
479366 Canis lupus familiaris
518502 Bos taurus
548799 Xenopus (Silurana) tropicalis
100173217 Pongo abelii
100528686 Ictalurus punctatus
740886 Pan troglodytes
5810 Homo sapiens
19355 Mus musculus
Selected quality suppliers for RAD1 Proteins (RAD1)
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