anti-RAD18 Homolog (S. Cerevisiae) (RAD18) Antibodies

The protein encoded by RAD18 is highly similar to S. Additionally we are shipping RAD18 Proteins (9) and RAD18 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RAD18 56852 Q9NS91
RAD18 58186 Q9QXK2
RAD18 362412  
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Top anti-RAD18 Antibodies at antibodies-online.com

Showing 10 out of 101 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RAD18 Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate WB Suggested Anti-RAD18  Antibody Titration: 0.2-1 µg/mL  Positive Control:.21_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to RAD18 on HeLa cell (antibody concentration 25 µg/mL). Western blot analysis of RAD18 over-expressed 293 cell line, cotransfected with RAD18 Validated Chimera RNAi used as specificity and loading control. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated WB The anti-Rad18 mAb (Imgenex Cat#ABIN252484) was diluted at 2 ug/ml and tested against 20 ug of HL-60 cell lysate. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Mouse Un-conjugated WB RAD18 monoclonal antibody (M03), clone 2B9. Western Blot analysis of RAD18 expression in Hela NE. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RAD18 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: COLO205 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IP Western Blot: RAD18 Antibody [ABIN253201] - Detection of Human RAD18 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-RAD18 antibody ABIN253201 used for IP at 3 mcg/mg lysate. RAD18 was also immunoprecipitated by rabbit anti- RAD18 antibody ABIN253202, which recognizes a downstream epitope.  Detection: Chemiluminescence with an exposure time of 3 seconds. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated IP, PLA, WB Western Blot and Immunoprecipitation: RAD18 Antibody [ABIN253202] - Detection of Human RAD18 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and 293T (T, 50 mcg) cells. Antibodies: Affinity purified rabbit anti- RAD18 antibody ABIN253202 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. RAD18 was also immunoprecipitated by rabbit anti-RAD18 antibody ABIN253201, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 30 seconds Proximity Ligation Assay: RAD18 Antibody [ABIN2532023] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human ATM (ABIN253202) and rabbit anti-human RAD18 (ABIN2532023). Image merged from DAPI (2ms) and Texas Red (200ms) exposures, 40X magnification. 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated IF, IHC (p), RNAi, ELISA, WB RAD18 monoclonal antibody (M01), clone 3H7 Western Blot analysis of RAD18 expression in Hela S3 NE . Immunofluorescence of monoclonal antibody to RAD18 on HeLa cell. [antibody concentration 25 ug/ml] 100 μg Log in to see 11 to 12 Days
$430.00
Details
Mouse Rabbit Un-conjugated IF, IP, IHC, WB 100 μg Log in to see 9 to 11 Days
$434.50
Details

RAD18 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine)


Rat (Rattus)
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Top referenced anti-RAD18 Antibodies

  1. Human Monoclonal RAD18 Primary Antibody for IF, IHC (p) - ABIN566046 : Hicks, Chute, Paulsen, Ragland, Howlett, Guéranger, Glover, Canman: Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links. in Molecular and cellular biology 2010 (PubMed)
    Show all 7 references for 566046

  2. Human Monoclonal RAD18 Primary Antibody for WB - ABIN393575 : Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: A Large-scale genetic association study of esophageal adenocarcinoma risk. in Carcinogenesis 2010 (PubMed)
    Show all 5 references for 393575

  3. Human Monoclonal RAD18 Primary Antibody for IF, WB - ABIN393742 : Yang, Moldovan, DAndrea: RAD18-dependent recruitment of SNM1A to DNA repair complexes by a ubiquitin-binding zinc finger. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for 393742

  4. Mouse (Murine) Polyclonal RAD18 Primary Antibody for IF, IP - ABIN2452085 : Sun, Yomogida, Sakao, Yamamoto, Yoshida, Watanabe, Morita, Araki, Yamamura, Tateishi: Rad18 is required for long-term maintenance of spermatogenesis in mouse testes. in Mechanisms of development 2009 (PubMed)
    Show all 4 references for 2452085

  5. Human Monoclonal RAD18 Primary Antibody for WB - ABIN252484 : Lyakhovich, Shekhar: Supramolecular complex formation between Rad6 and proteins of the p53 pathway during DNA damage-induced response. in Molecular and cellular biology 2003 (PubMed)
    Show all 2 references for 252484

  6. Human Polyclonal RAD18 Primary Antibody for IP, PLA - ABIN253202 : Williams, Longerich, Sung, Vaziri, Kupfer: The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI. in Blood 2011 (PubMed)
    Show all 2 references for 253202

  7. Human Polyclonal RAD18 Primary Antibody for ELISA, WB - ABIN1451241 : Zody, Garber, Sharpe, Young, Rowen, ONeill, Whittaker, Kamal, Chang, Cuomo, Dewar, FitzGerald, Kodira, Madan, Qin, Yang, Abbasi, Abouelleil, Arachchi, Baradarani, Birditt, Bloom, Bloom, Borowsky et al.: Analysis of the DNA sequence and duplication history of human chromosome 15. ... in Nature 2006 (PubMed)

  8. Cow (Bovine) Polyclonal RAD18 Primary Antibody for WB - ABIN2774765 : Tsuji, Watanabe, Araki, Shinohara, Yamagata, Tsurimoto, Hanaoka, Yamamura, Yamaizumi, Tateishi: Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks. in Genes to cells : devoted to molecular & cellular mechanisms 2008 (PubMed)

  9. Human Polyclonal RAD18 Primary Antibody for IP - ABIN253201 : Wagner, Karnitz: Cisplatin-induced DNA damage activates replication checkpoint signaling components that differentially affect tumor cell survival. in Molecular pharmacology 2009 (PubMed)

More Antibodies against RAD18 Interaction Partners

Human RAD18 Homolog (S. Cerevisiae) (RAD18) interaction partners

  1. Ubiquitin ligases RNF168 (show RNF168 Antibodies), RNF169 (show RNF169 Antibodies), and RAD18 specifically bind histone H2A Lys13/15-ubiquitylated nucleosomes. 53BP1 (show TP53BP1 Antibodies) chromatin recruitment may be activated by RNF168 (show RNF168 Antibodies) and blocked by RNF169 (show RNF169 Antibodies) and RAD18.

  2. WRNIP1 (show WRNIP1 Antibodies) connects PCNA (show PCNA Antibodies) monoubiquitination with ATMIN (show ATMIN Antibodies)/ATM (show ATM Antibodies) to activate ATM (show ATM Antibodies) signalling in response to replication stress and contribute to the maintenance of genomic stability.

  3. RAD18 polymorphisms are correlated with the side effects of platinum-chemotherapy in Chinese patients with advanced NSCLC.

  4. REV1 (show REV1 Antibodies) can promote (show PCNA Antibodies)PCNA monoubiquitylation after UV radiation through interacting with ubiquitylated RAD18.

  5. USP7 (show USP7 Antibodies)-mediated de-ubiquitylation protects Rad18 from proteasomal degradation and is necessary for the integrity of the specialized translesion synthesis pathway

  6. RAD18 can function as a mediator for DNA damage response signals to activate the G2/M checkpoint in order to maintain genome integrity and cell survival after IR exposure.

  7. Significantly restored tolerance of RAD18-/- and RNF8 (show RNF8 Antibodies)-/- cells to camptothecin and olaparib without affecting Rad51 (show RAD51 Antibodies) focus formation.

  8. these results suggest that miR (show MLXIP Antibodies)-145 can act as an RAD18 inhibitor and contribute as an important factor in reversing drug resistance after chemotherapy.

  9. We obtained a molecular envelope for Rad18 UBZ-ELRM:linear Ub2 polyubiquitin (show UBB Antibodies) chains by small-angle X-ray scattering and derived a structural model for the complex.

  10. Rad18 protein ubiquitin-binding zinc fingers domain has alpha-helix and strand beta1 conformation.

Mouse (Murine) RAD18 Homolog (S. Cerevisiae) (RAD18) interaction partners

  1. Somatic hypermutation of immunoglobulin genes (SHM (show CNTNAP1 Antibodies)) in Rad18 KO mice was similar to wild-type mice, suggesting that Rad18 is dispensable for SHM (show CNTNAP1 Antibodies).

  2. Rad18 confers DNA damage tolerance and tumor-suppression in a physiological setting.

  3. REV1 promote PCNA (show PCNA Antibodies) monoubiquitylation after UV radiation through interacting with ubiquitylated RAD18.

  4. RAD18 can function as a mediator for DNA damage response signals to activate the G2/M checkpoint in order to maintain genome integrity and cell survival after IR exposure.

  5. RAD18 contributes to maintenance of genomic stability through postreplication repair

  6. Rad18Sc localizes to the XY body and to other chromosomal regions that are unpaired and transcriptionally silenced during male meiotic prophase

  7. Rad18 suppresses viral infection in a non-specific fashion, probably by targeting incoming DNA.

  8. RAD18 is intrinsically required for the long-term maintenance of spermatogenesis.

RAD18 Antigen Profile

Protein Summary

The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.

Gene names and symbols associated with RAD18

  • RAD18 homolog (S. cerevisiae) (rad18) antibody
  • RAD18 homolog (S. cerevisiae) (RAD18) antibody
  • similar to postreplication repair protein hRAD18p (RAD18) antibody
  • E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair (RAD18) antibody
  • similar to S. cerevisiae RAD18 (YCR066W) ubiquitin conjugating enzyme involved in DNA repair, Zn finger protein; same as cosmid orf Ca20C1.14c (RAD18) antibody
  • DNA repair protein and ATPase (RAD18) antibody
  • C3HC4-type zinc finger-containing protein (rad18) antibody
  • RAD18 homolog (S. cerevisiae) (Rad18) antibody
  • 2810024C04Rik antibody
  • DDBDRAFT_0218120 antibody
  • DDBDRAFT_0304878 antibody
  • DDB_0218120 antibody
  • DDB_0304878 antibody
  • DKFZp469H0810 antibody
  • RAD18 antibody
  • Rad18sc antibody
  • RNF73 antibody
  • zgc:55577 antibody

Protein level used designations for RAD18

E3 ubiquitin-protein ligase RAD18 , RAD18 homolog (S. cerevisiae) , postreplication repair protein hRAD18p , similar to postreplication repair protein hRAD18p , E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair , Rad18p , hypothetical protein , DNA repair protein and ATPase , SAP DNA-binding domain-containing protein , RAD18 homolog , E3 ubiquitin-protein ligase RAD18-like , e3 ubiquitin-protein ligase RAD18-like , RAD18, S. cerevisiae, homolog , RING finger protein 73 , hHR18 , hRAD18 , postreplication repair protein RAD18 , RAD18-like protein , mRAD18Sc , post-replication repair protein RAD18SC

GENE ID SPECIES
393106 Danio rerio
460144 Pan troglodytes
704708 Macaca mulatta
850430 Saccharomyces cerevisiae S288c
3641637 Candida albicans SC5314
3641662 Candida albicans SC5314
4839641 Scheffersomyces stipitis CBS 6054
8621702 Dictyostelium discoideum AX4
100052645 Equus caballus
100172537 Pongo abelii
100395032 Callithrix jacchus
100473633 Ailuropoda melanoleuca
100591424 Nomascus leucogenys
56852 Homo sapiens
416114 Gallus gallus
476544 Canis lupus familiaris
100217383 Sus scrofa
514440 Bos taurus
58186 Mus musculus
362412 Rattus norvegicus
Selected quality suppliers for anti-RAD18 (RAD18) Antibodies
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