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RAN Binding Protein 1 (RANBP1) ELISA Kits

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. Additionally we are shipping RANBP1 Antibodies (47) and RANBP1 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human RANBP1 RANBP1 5902 P43487
Anti-Mouse RANBP1 RANBP1 19385 P34022
Anti-Rat RANBP1 RANBP1 360739  
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More ELISA Kits for RANBP1 Interaction Partners

Xenopus laevis RAN Binding Protein 1 (RANBP1) interaction partners

  1. findings reveal an important mitotic role for RanBP1, controlling the spatial distribution and magnitude of mitotic Ran-GTP (show AK3 ELISA Kits) production and thereby ensuring accurate execution of Ran-dependent mitotic events

Human RAN Binding Protein 1 (RANBP1) interaction partners

  1. Sgk1 (show SGK1 ELISA Kits)-dependent regulation of RANBP1 has functional consequences on both mitotic microtubule activity and taxol sensitivity of cancer cells.

  2. in vitro and in vivo phosphorylation of RanBP1 by Plk1 (show PLK1 ELISA Kits) as well as the importance of phosphorylation of RanBP1 in the interaction between Plk1 (show PLK1 ELISA Kits) and Ran during early mitosis, is demonstrated.

  3. RANBP1 on 22q11.21 locus might be causally related to the smooth pursuit eye movement abnormality rather than the development of schizophrenia.

  4. Downregulation of the Ran GTPase (show RAN ELISA Kits) effector RanBP1 is required for nuclear reorganisation.

  5. structure of the Ran-RanBP1-RanGAP complex

  6. Phosphorylated wild type RanGAP1 (show RANGAP1 ELISA Kits), but not a mutant harboring a mutation at the phosphorylation site 358S, efficiently formed a stable ternary complex with Ran and RanBP1 in vivo, suggesting that the 358S phosphorylation of RanGAP1 (show RANGAP1 ELISA Kits) affects the Ran system.

  7. These data indicate that RANBP1 activity is required for the proper localization of specific factors that regulate microtubule function; loss of this activity contributes to the generation of aneuploidy in a microtubule-dependent manner.

  8. RanBP1-interfered cells show an increased apoptotic response to taxol compared to their counterpart with normal or high RanBP1 levels, and this response is caspase-3 (show CASP3 ELISA Kits) dependent.

  9. Generation of Ran-GTP (show AK3 ELISA Kits) from Ran-GDP by importin-beta (show KPNB1 ELISA Kits) is activated by Ran-binding protein-1 (RanBP1) that forms a trimeric complex with Ran-GDP and importin-beta (show KPNB1 ELISA Kits).

Mouse (Murine) RAN Binding Protein 1 (RANBP1) interaction partners

  1. Ranbp1 emerges as a microcephaly gene within the 22q11.2 deleted region that may contribute to altered cortical precursor proliferation and neurogenesis associated with broader 22q11.2 deletion.

  2. Data suggest Ran activation by RanBP1 in macrophages promotes Legionella phagosome formation and phagocytosis; LegG1 functions as bacterial Ran activator, localizes to phagosomes, and promotes microtubule stabilization, phagocytosis, and replication.

  3. The dramatic decrease in "RanBP" activity impairs germ cell viability and affects spermatogenesis decisively in RanBP1-knockout mice.

  4. Downregulation of the Ran GTPase (show RAN ELISA Kits) effector RanBP1 is required for nuclear reorganisation.

  5. expressed in the frontonasal processes, branchial arches, aortic arches, and limb buds. At these sites, RanBP1 apparently coincides with neural crest-derived mesenchymal cells. In addition, RanBP1 is expressed in the forebrain

  6. RanBP1 interferes with crucial factor(s) that control structural and dynamic features of centrosomes during mitosis

  7. Tax (show CNTN2 ELISA Kits) directly binds Ran and Ran-binding protein-1, locates to centrosomes/spindle poles, and causes supernumerary centrosomes

RANBP1 Antigen Profile

Antigen Summary

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

Gene names and symbols associated with RANBP1

  • RAN binding protein 1 (ranbp1) antibody
  • Ran binding protein 1 (LOC397932) antibody
  • ran binding protein 1 (PVX_090070) antibody
  • RAN binding protein 1 (GL50803_16969) antibody
  • RAN binding protein 1 (LOC100343953) antibody
  • RAN binding protein 1 (RANBP1) antibody
  • RAN binding protein 1 (Ranbp1) antibody
  • hm:zeh1094 antibody
  • Htf9a antibody
  • MGC64314 antibody
  • wu:fa96a09 antibody
  • wu:fj39g07 antibody
  • zeh1094 antibody
  • zgc:85649 antibody

Protein level used designations for RANBP1

RAN binding protein 1 , Ran binding protein 1 , ran binding protein 1 , ran-specific GTPase-activating protein , HpaII tiny fragments locus 9A , Htf9-a/RanBP1 , hpaII tiny fragments locus 9a protein , ran-binding protein 1

379454 Xenopus laevis
397932 Xenopus laevis
5474397 Plasmodium vivax Sal-1
5701654 Giardia lamblia ATCC 50803
100343953 Oryctolagus cuniculus
337046 Danio rerio
5902 Homo sapiens
19385 Mus musculus
360739 Rattus norvegicus
533251 Bos taurus
416787 Gallus gallus
477563 Canis lupus familiaris
100151896 Sus scrofa
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