RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1) ELISA Kits

The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).[supplied by OMIM, Feb 2010].. Additionally we are shipping RAP1GDS1 Antibodies (54) and RAP1GDS1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat RAP1GDS1 RAP1GDS1 310909  
RAP1GDS1 5910 P52306
Anti-Mouse RAP1GDS1 RAP1GDS1 229877  
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Top RAP1GDS1 ELISA Kits at antibodies-online.com

Showing 3 out of 6 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.095 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 2 to 3 Days
$812.90
Details
Human 0.188 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 13 to 16 Days
$475.20
Details
Cow
96 Tests Log in to see 15 to 18 Days
$1,029.60
Details

More ELISA Kits for RAP1GDS1 Interaction Partners

Human RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1) interaction partners

  1. Data suggest that SmgGDS-558 splice variant exhibits a fold containing tandem copies of armadillo (show PKP1 ELISA Kits)-repeat motifs not present in other guanine nucleotide exchange factors (GEFs); SmgGDS harbors distinct positively and negatively charged regions, both of which play critical roles in binding to RhoA (show RHOA ELISA Kits) and in GEF activity. (SmgGDS = smg (show SNRPG ELISA Kits) p21 (show CDKN1A ELISA Kits) stimulatory GDP exchange protein; RhoA (show RHOA ELISA Kits) = ras homolog gene family, member A (show CXCL14 ELISA Kits))

  2. Unlike Rap1B (show RAP1B ELISA Kits), phosphorylation in the polybasic region of Rap1A (show RAP1A ELISA Kits) does not detectably inhibit its prenylation or its binding to SmgGDS-607.

  3. In addition, a PINK1 mutant, which induced mitochondrial enlargement and had been considered as a Drosophila model of Parkinson's disease (PD), caused fly muscle defects, and the loss of vimar could rescue these defects. Furthermore, we found that the mammalian homolog of Vimar, RAP1GDS1, played a similar role in regulating mitochondrial morphology, suggesting a functional conservation of this GEF member.

  4. results indicate that statins selectively up-regulate SmgGDS in endothelial cells, for which the beta1-integrin/Akt1 (show AKT1 ELISA Kits) pathway may be involved, demonstrating the novel aspects of the pleiotropic effects of statins

  5. DiRas1 (show DIRAS1 ELISA Kits) expression inhibits malignant features of cancers in part by nonproductively binding to SmgGDS and inhibiting the binding of other small GTPases to SmgGDS

  6. SmgGDS promotes cell cycle progression in multiple types of cancer, making SmgGDS a valuable target for cancer therapeutics.

  7. TG2 (show TGM2 ELISA Kits) contributes to apoptosis induction in Jurkat T cells by modulating Ca2 (show CA2 ELISA Kits)+ homeostasis via cross-linking RAP1GDS1.

  8. findings identify SmgGDS-558 as an activator of RhoA (show RHOA ELISA Kits) and NF-kB in breast cancer, and demonstrate a functional role for SmgGDS-558 in the proliferation of breast cancer cells and tumorigenesis.

  9. this study provides evidence that SmgGDS-607 associates with GTPases through recognition of the last amino acid in the CAAX motif.

  10. These results indicate that statins exert their pleiotropic effects through SmgGDS upregulation with a resultant Rac1 degradation and reduced oxidative stress in animals and humans.

Cow (Bovine) RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1) interaction partners

  1. These results identify SmgGDS as a novel regulator of myosin organization and contraction in vascular smooth muscle cells.

Mouse (Murine) RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1) interaction partners

  1. results indicate that statins selectively up-regulate SmgGDS in endothelial cells, for which the beta1-integrin/Akt1 (show AKT1 ELISA Kits) pathway may be involved, demonstrating the novel aspects of the pleiotropic effects of statins

  2. These results indicate that statins exert their pleiotropic effects through SmgGDS upregulation with a resultant Rac1 degradation and reduced oxidative stress in animals and humans.

RAP1GDS1 Antigen Profile

Antigen Summary

The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993

Gene names and symbols associated with RAP1GDS1

  • RAP1, GTP-GDP dissociation stimulator 1 (Rap1gds1) antibody
  • RAP1, GTP-GDP dissociation stimulator 1 (LOC100217715) antibody
  • RAP1, GTP-GDP dissociation stimulator 1 (RAP1GDS1) antibody
  • RAP1, GTP-GDP dissociation stimulator 1 (rap1gds1-a) antibody
  • BC011279 antibody
  • gds1 antibody
  • rap1gds1 antibody
  • smgGDS antibody
  • XsmgGDS antibody

Protein level used designations for RAP1GDS1

rap1 GTPase-GDP dissociation stimulator 1 , RAP1, GTP-GDP dissociation stimulator 1 , SMG GDS protein , SMG P21 stimulatory GDP/GTP exchange protein , exchange factor smgGDS , ralB-binding protein A , rap1 GTPase-GDP dissociation stimulator 1-A , smgGDS-A , xsmgGDS-A

GENE ID SPECIES
310909 Rattus norvegicus
100217715 Taeniopygia guttata
5910 Homo sapiens
282516 Bos taurus
229877 Mus musculus
394369 Xenopus laevis
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