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anti-RAP1 GTPase Activating Protein (RAP1GAP) Antibodies

RAP1GAP encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. Additionally we are shipping RAP1 GTPase Activating Protein Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RAP1GAP 5909 P47736
RAP1GAP 110351  
RAP1GAP 313644  
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Top anti-RAP1 GTPase Activating Protein Antibodies at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RAP1GAP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate WB Suggested Anti-RAP1GAP  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control:.93T cell lysate  RAP1GAP is supported by BioGPS gene expression data to be expressed in HEK293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-RAP1GAP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Transfected 293T WB Suggested Anti-RAP1GAP  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of RAP1GAP staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of RAP1GAP expression in Jurkat (A), HeLa (B), mouse brain (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat pancreas labeled with Anti-RAP1GAP Polyclonal Antibody, Unconjugated (ABIN681673) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged RAP1GA1 is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB RAP1GAP antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IHC   100 μL Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated IHC   100 μL Log in to see 8 to 10 Days
$375.83
Details

RAP1GAP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
,
,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-RAP1 GTPase Activating Protein Antibodies

  1. Cow (Bovine) Polyclonal RAP1GAP Primary Antibody for WB - ABIN2786745 : Mitra, Goto, Lee, Maldonado, Taylor, Pan, Carey, Bradford, Prince, Cordell, Kirkwood, DSilva: Rap1GAP promotes invasion via induction of matrix metalloproteinase 9 secretion, which is associated with poor survival in low N-stage squamous cell carcinoma. in Cancer research 2008 (PubMed)

More Antibodies against RAP1 GTPase Activating Protein Interaction Partners

Zebrafish RAP1 GTPase Activating Protein (RAP1GAP) interaction partners

  1. a proper level of Rap1 is crucial for heart morphogenesis and function.

  2. the direct interaction between Rap1 and KRIT1 is required for KRIT1 (show TERF2IP Antibodies)function in (show KRIT1 Antibodies) cardiovascular development

Human RAP1 GTPase Activating Protein (RAP1GAP) interaction partners

  1. Rap1GAP is ubiquitinated and degraded through proteasome pathway in mitosis. Rap1GAP interacts with PLK1 (show PLK1 Antibodies) in vivo.

  2. this study demonstrates that USP48 (show USP48 Antibodies) controls the Ubiquitin/proteasome-system-dependent turnover of activated NF-kappaB (show NFKB1 Antibodies)/RelA (show NFkBP65 Antibodies) in the nucleus.

  3. Northern blot analysis revealed a single USP31 (show USP31 Antibodies) transcript of approximately 4 kb, which was primarily expressed in the testis and lung.

  4. The Overexpression of USP31 (show USP31 Antibodies) in HEK (show EPHA3 Antibodies) 293T cells inhibited TNFalpha (show TNF Antibodies), CD40 (show CD40 Antibodies), LMP1 (show PDLIM7 Antibodies), TRAF2 (show TRAF2 Antibodies), TRAF6 (show TRAF6 Antibodies) and IKKbeta (show IKBKB Antibodies)-mediated NF-kappaB (show NFKB1 Antibodies) activation, but did not inhibit Smad (show SMAD1 Antibodies)-mediated transcription activation.

  5. kidney biopsies from glomerulosclerosis patients exhibited increased RAP1GAP, resulting in diminished glomerular RAP1 activation

  6. data demonstrate a crucial role for the dynamic interaction between D3R and USP48 (show USP48 Antibodies) in the regulation of NHE3 (show SLC9A3 Antibodies) expression and function

  7. findings identify Rap1GAP as a critical regulator of aggressive tumor cell behavior and suggest that the level of Rap1GAP expression influences the migratory mechanisms that are operative in tumor cells.

  8. Results demonstrated that Rap1GAP promoted leukemia cell differentiation and apoptosis, but increased leukemia cell invasion in vitro.

  9. Downregulation of RAP1GAP in thyroid tumors enhances SRC (show SRC Antibodies)-dependent signals that regulate cellular architecture and motility.

  10. Over-expression of Rap1GAP attenuated levels of both cadherins and integrins that are known to regulate the cancer cells invasion in renal cel carcinoma.

Mouse (Murine) RAP1 GTPase Activating Protein (RAP1GAP) interaction partners

  1. increased podocyte expression of RAP1GAP contributes directly to podocyte dysfunction by a mechanism that involves loss of RAP1-mediated activation of beta1 integrin

  2. Plexins are GTPase (show RACGAP1 Antibodies)-activating proteins for Rap (show LRPAP1 Antibodies) and are activated by induced dimerization

  3. Ca2 (show CA2 Antibodies)+-dependent monomer and dimer formation switches CAPRI (show RASA4 Antibodies) Protein between Ras GTPase-activating protein (show RASA1 Antibodies) (GAP) and RapGAP activities

  4. ERK activation by cAMP does not require RAP1

  5. evidence of differential Krit1 (show KRIT1 Antibodies) and Rap1A (show RAP1A Antibodies) expression during mouse ontogenesis and suggest a more widespread functional significance of Krit1 (show KRIT1 Antibodies), not restricted to vascular endothelial cells.

  6. Rap1 (show TERF2IP Antibodies) couples cAMP signaling to a distinct pool of p42 (show EPB42 Antibodies)/44MAPK regulating excitability, synaptic plasticity, learning, and memory.

  7. Expression studies show that mr-gef (show RAPGEF5 Antibodies) is expressed by young neurons of the developing rodent CNS but not by progenitor cells in the ventricular zone (VZ).

  8. down-regulation of Rap1 (show TERF2IP Antibodies) expression following somatostatin (show SST Antibodies) treatment is closely related to the diminished LFA-1 (show ITGAL Antibodies) expression

  9. forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling

  10. EGF (show EGF Antibodies)-induced activation of GTPase (show RACGAP1 Antibodies) Rap1 (show TERF2IP Antibodies) was sensitized in NIH3T3/EGFR (show EGFR Antibodies)-e3B1 (show ABI1 Antibodies) cells.

RAP1 GTPase Activating Protein (RAP1GAP) Antigen Profile

Protein Summary

This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with RAP1GAP

  • RAP1 GTPase activating protein (LOC395647) antibody
  • Rap1 GTPase-activating protein 1 (Tsp_09520) antibody
  • RAP1 GTPase activating protein (rap1gap) antibody
  • RAP1 GTPase activating protein (RAP1GAP) antibody
  • Rap1 GTPase-activating protein (Rap1gap) antibody
  • ubiquitin specific peptidase 48 (USP48) antibody
  • 1300019I11Rik antibody
  • 2310004O14Rik antibody
  • AI427470 antibody
  • DKFZp459A114 antibody
  • RAP1 antibody
  • Rap1ga1 antibody
  • RAP1GAP antibody
  • rap1gap1 antibody
  • rap1gapii antibody
  • rapgap antibody
  • USP31 antibody
  • zgc:175180 antibody

Protein level used designations for RAP1GAP

GTPase activating protein 1 , GTPase activating protein Rap1-GAP , RAP1, GTPase activating protein 1 , Rap1 GTPase-activating protein 1 , rap1 GTPase-activating protein 1 , Rap1, GTPase-activating protein 1 , deubiquitinating enzyme 48 , ubiquitin carboxyl-terminal hydrolase 48 , ubiquitin specific protease 31 , ubiquitin specific protease 48 , ubiquitin thioesterase 48 , ubiquitin thiolesterase 48 , ubiquitin-specific-processing protease 48

GENE ID SPECIES
395647 Gallus gallus
10902864 Trichinella spiralis
100144557 Danio rerio
100172787 Pongo abelii
5909 Homo sapiens
100538309 Danio rerio
494835 Xenopus laevis
532839 Bos taurus
110351 Mus musculus
313644 Rattus norvegicus
84196 Homo sapiens
Selected quality suppliers for anti-RAP1 GTPase Activating Protein (RAP1GAP) Antibodies
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