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RAP1 GTPase Activating Protein (RAP1GAP) ELISA Kits

RAP1GAP encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. Additionally we are shipping RAP1 GTPase Activating Protein Antibodies (28) and RAP1 GTPase Activating Protein Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human RAP1GAP RAP1GAP 5909 P47736
Anti-Mouse RAP1GAP RAP1GAP 110351  
Anti-Rat RAP1GAP RAP1GAP 313644  
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More ELISA Kits for RAP1 GTPase Activating Protein Interaction Partners

Zebrafish RAP1 GTPase Activating Protein (RAP1GAP) interaction partners

  1. a proper level of Rap1 is crucial for heart morphogenesis and function.

  2. the direct interaction between Rap1 and KRIT1 is required for KRIT1 (show TERF2IP ELISA Kits)function in (show KRIT1 ELISA Kits) cardiovascular development

Human RAP1 GTPase Activating Protein (RAP1GAP) interaction partners

  1. Rap1GAP is ubiquitinated and degraded through proteasome pathway in mitosis. Rap1GAP interacts with PLK1 (show PLK1 ELISA Kits) in vivo.

  2. this study demonstrates that USP48 (show USP48 ELISA Kits) controls the Ubiquitin/proteasome-system-dependent turnover of activated NF-kappaB (show NFKB1 ELISA Kits)/RelA (show NFkBP65 ELISA Kits) in the nucleus.

  3. Northern blot analysis revealed a single USP31 transcript of approximately 4 kb, which was primarily expressed in the testis and lung.

  4. The Overexpression of USP31 in HEK (show EPHA3 ELISA Kits) 293T cells inhibited TNFalpha (show TNF ELISA Kits), CD40 (show CD40 ELISA Kits), LMP1 (show PDLIM7 ELISA Kits), TRAF2 (show TRAF2 ELISA Kits), TRAF6 (show TRAF6 ELISA Kits) and IKKbeta (show IKBKB ELISA Kits)-mediated NF-kappaB (show NFKB1 ELISA Kits) activation, but did not inhibit Smad (show SMAD1 ELISA Kits)-mediated transcription activation.

  5. kidney biopsies from glomerulosclerosis patients exhibited increased RAP1GAP, resulting in diminished glomerular RAP1 activation

  6. data demonstrate a crucial role for the dynamic interaction between D3R and USP48 (show USP48 ELISA Kits) in the regulation of NHE3 (show SLC9A3 ELISA Kits) expression and function

  7. findings identify Rap1GAP as a critical regulator of aggressive tumor cell behavior and suggest that the level of Rap1GAP expression influences the migratory mechanisms that are operative in tumor cells.

  8. Results demonstrated that Rap1GAP promoted leukemia cell differentiation and apoptosis, but increased leukemia cell invasion in vitro.

  9. Downregulation of RAP1GAP in thyroid tumors enhances SRC (show SRC ELISA Kits)-dependent signals that regulate cellular architecture and motility.

  10. Over-expression of Rap1GAP attenuated levels of both cadherins and integrins that are known to regulate the cancer cells invasion in renal cel carcinoma.

Mouse (Murine) RAP1 GTPase Activating Protein (RAP1GAP) interaction partners

  1. increased podocyte expression of RAP1GAP contributes directly to podocyte dysfunction by a mechanism that involves loss of RAP1-mediated activation of beta1 integrin

  2. Plexins are GTPase (show RACGAP1 ELISA Kits)-activating proteins for Rap (show LRPAP1 ELISA Kits) and are activated by induced dimerization

  3. Ca2 (show CA2 ELISA Kits)+-dependent monomer and dimer formation switches CAPRI (show RASA4 ELISA Kits) Protein between Ras GTPase-activating protein (show RASA1 ELISA Kits) (GAP) and RapGAP activities

  4. ERK activation by cAMP does not require RAP1

  5. evidence of differential Krit1 (show KRIT1 ELISA Kits) and Rap1A (show RAP1A ELISA Kits) expression during mouse ontogenesis and suggest a more widespread functional significance of Krit1 (show KRIT1 ELISA Kits), not restricted to vascular endothelial cells.

  6. Rap1 (show TERF2IP ELISA Kits) couples cAMP signaling to a distinct pool of p42 (show EPB42 ELISA Kits)/44MAPK regulating excitability, synaptic plasticity, learning, and memory.

  7. Expression studies show that mr-gef (show RAPGEF5 ELISA Kits) is expressed by young neurons of the developing rodent CNS but not by progenitor cells in the ventricular zone (VZ).

  8. down-regulation of Rap1 (show TERF2IP ELISA Kits) expression following somatostatin (show SST ELISA Kits) treatment is closely related to the diminished LFA-1 (show ITGAL ELISA Kits) expression

  9. forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB (show CREB ELISA Kits)) and Epac1 (show RAPGEF3 ELISA Kits)-Rap1 (show TERF2IP ELISA Kits) signaling

  10. EGF (show EGF ELISA Kits)-induced activation of GTPase (show RACGAP1 ELISA Kits) Rap1 (show TERF2IP ELISA Kits) was sensitized in NIH3T3/EGFR (show EGFR ELISA Kits)-e3B1 (show ABI1 ELISA Kits) cells.

RAP1 GTPase Activating Protein (RAP1GAP) Antigen Profile

Antigen Summary

This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with RAP1GAP

  • RAP1 GTPase activating protein (LOC395647) antibody
  • Rap1 GTPase-activating protein 1 (Tsp_09520) antibody
  • RAP1 GTPase activating protein (rap1gap) antibody
  • RAP1 GTPase activating protein (RAP1GAP) antibody
  • Rap1 GTPase-activating protein (Rap1gap) antibody
  • ubiquitin specific peptidase 48 (USP48) antibody
  • 1300019I11Rik antibody
  • 2310004O14Rik antibody
  • AI427470 antibody
  • DKFZp459A114 antibody
  • RAP1 antibody
  • Rap1ga1 antibody
  • RAP1GAP antibody
  • rap1gap1 antibody
  • rap1gapii antibody
  • rapgap antibody
  • USP31 antibody
  • zgc:175180 antibody

Protein level used designations for RAP1GAP

GTPase activating protein 1 , GTPase activating protein Rap1-GAP , RAP1, GTPase activating protein 1 , Rap1 GTPase-activating protein 1 , rap1 GTPase-activating protein 1 , Rap1, GTPase-activating protein 1 , deubiquitinating enzyme 48 , ubiquitin carboxyl-terminal hydrolase 48 , ubiquitin specific protease 31 , ubiquitin specific protease 48 , ubiquitin thioesterase 48 , ubiquitin thiolesterase 48 , ubiquitin-specific-processing protease 48

395647 Gallus gallus
10902864 Trichinella spiralis
100144557 Danio rerio
100172787 Pongo abelii
5909 Homo sapiens
100538309 Danio rerio
494835 Xenopus laevis
532839 Bos taurus
110351 Mus musculus
313644 Rattus norvegicus
84196 Homo sapiens
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