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human homolog is a GTPase and member of the RAS oncogene family [RGD, Feb 2006].. Additionally we are shipping RAP2A Antibodies (29) and RAP2A Proteins (7) and many more products for this protein.
The small GTPase (show RACGAP1 ELISA Kits) Ras-related protein (show RASD1 ELISA Kits) 2 (Rap2) was found to bind ArrB1 (show ARRB1 ELISA Kits) under resting conditions but dissociated upon formyl-Met-Leu-Phe stimulation.
Nedd4-1 (show NEDD4 ELISA Kits) inhibited Rap2a activity, and promoted the migration and invasion of glioma cells.
present review mainly focused on recent studies on the functional and physical interactions between Rap2 and its effectors. We also speculated on the relevance of these pathways to tumorigenesis
Single nucleotide polymorphism in RAP2A gene is associated with Peripheral Arterial Disease.
the role of Rap2a in carcinogenesis
The ectopic expression of Rap2a enhances the migration and invasive ability of cancer cells and increases activities of matrix metalloproteinase MMP2 (show MMP2 ELISA Kits) and MMP9 (show MMP9 ELISA Kits).
Phosphorylation of synaptic GTPase-activating protein (show RASA1 ELISA Kits) (synGAP (show SYNGAP1 ELISA Kits)) by Ca2+/calmodulin-dependent protein kinase II (CaMKII (show CAMK2 ELISA Kits)) and cyclin-dependent kinase 5 (CDK5 (show CDK5 ELISA Kits)) alters the ratio of its GAP activity toward Ras and Rap (show LRPAP1 ELISA Kits) GTPases.
downregulation of Rap2a promoted glioma migration and invasion, and raised the phosphorylation level of AKT (show AKT1 ELISA Kits)
endothelial barrier resistance is determined by the combined antagonistic actions of Rap1 (show RABGEF1 ELISA Kits) and Rap2
Rap2A and TNIK (show TNIK ELISA Kits) control brush border formation by apical recruitment of MST4 and the subsequent phosphorylation of Ezrin (show EZR ELISA Kits)
BCR (show BCR ELISA Kits)-induced phosphorylation of Akt (show AKT1 ELISA Kits) on critical activating sites was increased 2- to 3-fold when Rap1 (show TERF2IP ELISA Kits) and Rap2 activation was blocked
Rap2 has a role in regulation of integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 (show PTK2B ELISA Kits) tyrosine phosphorylation in B lymphocytes
human homolog is a GTPase and member of the RAS oncogene family
ras-related protein Rap-2a
, RAS related protein 2a inverted question mark
, rap2A-like protein
, RAP2A, member of RAS oncogene family
, Rap2A GTPase
, RAP2, member of RAS oncogene family (K-rev)
, RAP2B member of RAS oncogene family
, Ras-related protein Rap-2a