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This intronless gene belongs to a family of RAS-related genes. Additionally we are shipping RAP2B Proteins (8) and many more products for this protein.
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Western blot analysis uncovered that elevated Rap2B leads to increased phosphorylation levels of FAK (show PTK2 Antibodies), suggesting that FAK (show PTK2 Antibodies)-dependent pathway might be responsible for the effect of Rap2B on PCa (show FLVCR1 Antibodies) cells migration and invasion.
Expression and DNA methylation (show HELLS Antibodies) status of the Rap2B gene in human bronchial epithelial cells treated by cigarette smoke condensate
Our collective findings provide preliminary evidence that miR (show MLXIP Antibodies)-342-3p acts as a tumor suppressor in small cell lung cancer through repression of RAP2B.
Rap2B itself is not necessary for p53 (show TP53 Antibodies)-dependent cell cycle arrest.
Data indicate that rap (show LRPAP1 Antibodies) GTP-binding protein Rap2B expression is significantly increased in suprarenal epithelioma and Rap2B can promote the cell migration and invasion abilities, suggesting a target for the treatment of suprarenal epithelioma.
Rap2b mediates the pro-survival function of p53 (show TP53 Antibodies) upon DNA damage.
Stimulation of phospholipase C-epsilon (show PLCL1 Antibodies) by the M3 muscarinic acetylcholine receptor (show CHRM3 Antibodies) mediated by cyclic AMP (show APRT Antibodies) and the GTPase (show RACGAP1 Antibodies) Rap2B
the small GTPase (show RACGAP1 Antibodies) Rap2B is involved in platelet activation
A cDNA library consisting of 220 upregulated genes in tumour tissue was established and named as LSCC. Differential expression was confirmed in five of these genes, including IGFBP5 (show IGFBP5 Antibodies), SQLE (show SQLE Antibodies), RAP2B, CLDN1 (show CLDN1 Antibodies), and TBL1XR1 (show TBL1XR1 Antibodies).
These results demonstrate that Rap2b, but not the more abundant Rap1b (show RAP1B Antibodies), is associated to lipid rafts in human platelets.
Taken together, these findings shed light on Rap2B as a therapeutic target for breast cancer.
the putative Rap2 (show RAP2A Antibodies) binding site of the RPIPx (show RUFY3 Antibodies) RUN domain interacts with the extended segment in a segment-swapping manner
This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated.
RAP2B, member of RAS oncogene family
, ras-related protein Rap-2b
, ras-dva small GTPase
, ras-like small GTPase
, small GTP binding protein