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This intronless gene belongs to a family of RAS-related genes. Additionally we are shipping RAP2B Antibodies (89) and many more products for this protein.
Showing 8 out of 8 products:
Human RAP2B Protein expressed in Escherichia coli (E. coli) - ABIN1098540
Béranger, Tavitian, de Gunzburg: Post-translational processing and subcellular localization of the Ras-related Rap2 protein. in Oncogene 1991
Show all 2 references for ABIN1098540
our results suggested that Rap2b may be a potential therapeutic target for lung cancer.
knockdown of Rap2B inhibits the proliferation and invasion in HCC (show FAM126A Proteins) cells. These findings reveal that Rap2B plays an important role in the regulation of HCC (show FAM126A Proteins) progression.
miR (show MLXIP Proteins)-194 is inversely correlated with RAP2B.
Western blot analysis uncovered that elevated Rap2B leads to increased phosphorylation levels of FAK (show PTK2 Proteins), suggesting that FAK (show PTK2 Proteins)-dependent pathway might be responsible for the effect of Rap2B on PCa (show FLVCR1 Proteins) cells migration and invasion.
Expression and DNA methylation (show HELLS Proteins) status of the Rap2B gene in human bronchial epithelial cells treated by cigarette smoke condensate
Our collective findings provide preliminary evidence that miR (show MLXIP Proteins)-342-3p acts as a tumor suppressor in small cell lung cancer through repression of RAP2B.
Rap2B itself is not necessary for p53 (show TP53 Proteins)-dependent cell cycle arrest.
Data indicate that rap (show LRPAP1 Proteins) GTP-binding protein Rap2B expression is significantly increased in suprarenal epithelioma and Rap2B can promote the cell migration and invasion abilities, suggesting a target for the treatment of suprarenal epithelioma.
Rap2b mediates the pro-survival function of p53 (show TP53 Proteins) upon DNA damage.
Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor (show CHRM3 Proteins) mediated by cyclic AMP (show APRT Proteins) and the GTPase (show RACGAP1 Proteins) Rap2B
Taken together, these findings shed light on Rap2B as a therapeutic target for breast cancer.
the putative Rap2 (show RAP2A Proteins) binding site of the RPIPx (show RUFY3 Proteins) RUN domain interacts with the extended segment in a segment-swapping manner
This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated.
RAP2B, member of RAS oncogene family
, ras-related protein Rap-2b
, ras-dva small GTPase
, ras-like small GTPase
, small GTP binding protein