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RAR-Related Orphan Receptor alpha Proteins (RORA)

The protein encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. Additionally we are shipping RORA Antibodies (2) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RORA 6095 P35398
Mouse RORA RORA 19883 P51448
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Top RORA Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$753.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$936.27
Details

RORA Proteins by Origin and Source

Origin Expressed in Conjugate
Human

More Proteins for RAR-Related Orphan Receptor alpha (RORA) Interaction Partners

Human RAR-Related Orphan Receptor alpha (RORA) interaction partners

  1. The RORA intronic SNP rs11632098 was associated with greater odds of reporting depressive symptoms in older adults.

  2. A common SNP in the RORA gene (rs2899663) was associated with a 21% reduced odds of placental abruption.

  3. In a Han Chinese population, an association between RORA gene variation and depression personality trait was found.

  4. associations between NR1D1 (show NR1D1 Proteins), RORA and RORB (show RORB Proteins) genes and bipolar disorder.(

  5. the data presented in this report are that RORA is linked in important ways to molecules that could be playing important roles in the AD etiology.

  6. Retinoic acid receptor-related orphan receptor-alpha (RORalpha) may be a potential risk gene for chronic obstructive pulmonary disease (COPD (show ARCN1 Proteins)).

  7. RORA variants were associated with dyslipidemia and obesity in Mexicans.

  8. RORA rs12912233 alone might be a possible risk variant for epilepsy in Malaysian Chinese, but that, together with RORA rs880626 and SCN1A (show SCN1A Proteins) rs3812718, this polymorphism may have a synergistic effect in the epilepsy risk in Malaysians.

  9. A cluster of RORA SNPs around rs2083074 showed an effect on psychic adverse drug reactions in the bipolar disorder.

  10. RORalpha mediates reprogramming of glucose metabolism in hepatoma cells in response to glutamine deficiency.

Mouse (Murine) RAR-Related Orphan Receptor alpha (RORA) interaction partners

  1. RORalpha regulates pathologic retinal angiogenesis by modulating SOCS3 (show SOCS3 Proteins)-dependent inflammation

  2. This study showed that spontaneous Rora mutations causing cerebellar pathology are impaired in motor functions during the neonatal period.

  3. the inhibition of NF-kappaB (show NFKB1 Proteins) by melatonin, but not that of NLRP3 (show NLRP3 Proteins), was blunted in RORalpha (sg/sg) mice, indicating that functional RORalpha transcription factor is necessary for the initiation of the innate immune response against inflammation.

  4. Rora induces the mRNA level of antioxidant enzymes, superoxide dismutase 2 (show SOD2 Proteins) and glutathione peroxidase 1 (show GPX1 Proteins), through the Rora response elements located in the upstream promoters of Sod2 (show SOD2 Proteins) and Gpx1 (show GPX1 Proteins).

  5. The nuclear receptors retinoic acid receptor (show RARA Proteins)-related orphan receptors-alpha and gammat (RORalpha and RORgammat) play critical roles in the development of TH17 cells.

  6. RORalpha is a transcriptional activator of insulin (show INS Proteins).

  7. Corl2/Skor2 has a role in regulating cerebellar Purkinje cell differentiation in a pathway involving RORalpha

  8. RORalpha is a key regulator of diurnal rhythm and fasting induction of CYP8B1 (show CYP8B1 Proteins), which regulates bile acid composition and serum and liver cholesterol levels.

  9. This study suggests an autocrine Wnt5a (show WNT5A Proteins)-Ror signaling pathway that directs sympathetic axon branching during target innervation.

  10. Disruption of Roralpha1 and cholesterol 25-hydroxylase (show CH25H Proteins) expression attenuates phagocytosis in male Roralphasg/sg mice.

RORA Protein Profile

Protein Summary

The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with RORA

  • RAR-related orphan receptor A (RORA)
  • RAR-related orphan receptor alpha (Rora)
  • 9530021D13Rik protein
  • nmf267 protein
  • Nr1f1 protein
  • ROR1 protein
  • ROR2 protein
  • ROR3 protein
  • RZR-ALPHA protein
  • RZRA protein
  • sg protein
  • staggerer protein
  • tmgc26 protein

Protein level used designations for RORA

ROR-alpha , nuclear receptor ROR-alpha , nuclear receptor RZR-alpha , nuclear receptor subfamily 1 group F member 1 , retinoic acid receptor-related orphan receptor alpha , retinoid-related orphan receptor alpha , thyroid hormone nuclear receptor alpha variant 4 , transcription factor RZR-alpha , retinoid-related orphan receptor-alpha

GENE ID SPECIES
6095 Homo sapiens
19883 Mus musculus
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