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The protein encoded by REM1 is a GTPase and member of the RAS-like GTP-binding protein family. Additionally we are shipping RAS (RAD and GEM)-Like GTP-Binding 1 Antibodies (31) and RAS (RAD and GEM)-Like GTP-Binding 1 Proteins (5) and many more products for this protein.
These results reveal that similar molecular determinants on Rem are repurposed to initiate 2 independent mechanisms of CaV1.2 (show CACNA1C ELISA Kits) inhibition.
Rad, Gem (show GEM ELISA Kits) and Rem all reduce depolarization-dependent Ca2 (show CA2 ELISA Kits)+ entry in developing myotubes.
amino-termini of Rad and Rem as the structural elements dictating the specific modes of inhibition of CaV1.1 (show CACNA1S ELISA Kits)
Loss of an REM1 protein increased L-type calcium current density in vivo in cardiac myocytes.
both Rem and Rad bind directly to Ca2 (show CA2 ELISA Kits)+ channel beta-subunits (CaV (show CA5A ELISA Kits) beta) in vivo
We conclude that Rem is capable of regulating L-type current, that release of Rem block is modulated by cellular kinase pathways, and that the Ca(V)1.2 (show CACNA1C ELISA Kits) COOH terminus contributes to Rem-dependent channel inhibition.
Rem-dependent Ca2 (show CA2 ELISA Kits)+ channel modulation involves formation of a Rem x CaVbeta x alpha-interaction domain regulatory complex without the need to disrupt CaValpha1 x CaVbeta association or alter CaValpha1 expression at the plasma membrane.
Nuclear localization of RGK proteins (Rad, Rem, and Rem2 (show REM2 ELISA Kits)) contributes to the suppression of RGK-mediated cell shape remodeling.
a role for the Rem C terminus in plasma membrane localization through association with phosphatidylinositol lipids.
The protein encoded by this gene is a GTPase and member of the RAS-like GTP-binding protein family. The encoded protein is expressed in endothelial cells, where it promotes reorganization of the actin cytoskeleton and morphological changes in the cells.
GTP-binding protein REM 1
, RAS-like GTP binding protein Rem
, rad and Gem-like GTP-binding protein 1
, GTPase-regulating endothelial cell sprouting
, rad and gem related GTP binding protein 1