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RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) Proteins (RASGRP3)

Members of the RAS (see HRAS\; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Additionally we are shipping RASGRP3 Antibodies (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RASGRP3 25780 Q8IV61
Rat RASGRP3 RASGRP3 313874  
Mouse RASGRP3 RASGRP3 240168  
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Top RASGRP3 Proteins at antibodies-online.com

Showing 3 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RASGRP3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3) Interaction Partners

Human RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3) interaction partners

  1. Knockdown of RasGRP3 inhibited proliferation in prostate neoplasms.

  2. Ras activator RasGRP3 may have a role in the pathological behavior of breast cancer cells and may constitute a therapeutic target for human breast cancer.

  3. The identification of the role of RasGRP3 in melanoma highlights its importance, as a Ras activator, in the phosphoinositide signaling pathway in human melanoma.

  4. Significant associations were found for the single nucleotide polymorphism rs13385731 of RasGRP3 with malar rash, discoid rash, and antinuclear antibody in patients with systemic lupus erythematosus

  5. RasGRP3 contributes to the malignant phenotype of prostate cancer cells and may constitute a novel therapeutic target for human prostate cancer.

  6. A vascular gene trap screen defines RASGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters.

  7. studies support the hypothesis that RasGRP phosphorylation by PKC is a mechanism that integrates DAG signaling systems in T and B cells

  8. dynein light chain 1 represents a novel anchoring protein for RasGRP3 that may regulate subcellular localization of the exchange factor

Mouse (Murine) RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3) interaction partners

  1. RasGRP3 limits inflammatory response by activating Rap1 on low-intensity pathogen infection, setting a threshold for preventing excessive inflammatory response.

  2. RasGRP1 (show RASGRP1 Proteins), but not RasGRP3, is required for thymocyte positive selection and invariant natural killer T cell selection.

  3. Expressed in developing blood vessels, Rasgrp3 contributes to the incidence of cardiovascular defects found in embryos from diabetic mothers.

RASGRP3 Protein Profile

Protein Summary

Members of the RAS (see HRAS\; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000

Gene names and symbols associated with RASGRP3

  • RAS guanyl releasing protein 3 (calcium and DAG-regulated) (RASGRP3)
  • RAS guanyl releasing protein 3 (calcium and DAG-regulated) (rasgrp3)
  • RAS guanyl releasing protein 3 (calcium and DAG-regulated) (LOC100229237)
  • RAS guanyl releasing protein 3 (calcium and DAG-regulated) (Rasgrp3)
  • RAS, guanyl releasing protein 3 (Rasgrp3)
  • BC066069 protein
  • Gm327 protein
  • GRP3 protein
  • RASGRP3 protein
  • zgc:162151 protein

Protein level used designations for RASGRP3

RAS guanyl releasing protein 3 (calcium and DAG-regulated) , ras guanyl-releasing protein 3 , ras guanyl-releasing protein 3-like , calcium and DAG-regulated guanine nucleotide exchange factor III , guanine nucleotide exchange factor for Rap1 , RAS, guanyl releasing protein 3

GENE ID SPECIES
470348 Pan troglodytes
523745 Bos taurus
563441 Danio rerio
611329 Canis lupus familiaris
707225 Macaca mulatta
100070505 Equus caballus
100171706 Pongo abelii
100229237 Taeniopygia guttata
100487452 Xenopus (Silurana) tropicalis
100539029 Meleagris gallopavo
100560305 Anolis carolinensis
100603635 Nomascus leucogenys
25780 Homo sapiens
313874 Rattus norvegicus
240168 Mus musculus
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