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RASEF is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. Additionally we are shipping RASEF Proteins (4) and many more products for this protein.
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Near-genomewide RNAi screening for regulators of BRAF (show BRAF Antibodies)(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma.
overexpression of RAB45 increased the phosphorylation levels of p38, resulting in the induction of apoptosis and inhibition of proliferation of CML progenitor cells
Homozygosity, in combination with methylation, appears to be the mechanism targeting RASEF in uveal melanoma, and allelic imbalance at this locus supports a TSG (show TWSG1 Antibodies) role for RASEF.
Results show elevated RASEF promoted cell growth via enhanced ERK (show EPHB2 Antibodies) signaling and is associated with poor prognosis of non-small cell lung carcinoma (NSCLC)
This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene.
ras and EF-hand domain-containing protein
, ras-related protein Rab-45
, ras and EF-hand domain-containing protein homolog