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RBAK encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. Additionally we are shipping RBAK Antibodies (41) and many more products for this protein.
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Studies indicate that data on the regulatory functions of the KRAB-ZFP (show ZNF167 Proteins) in embryonic development and tumorgenesis will benefit the understanding of biological roles of KRAB-ZFP (show ZNF167 Proteins) in different physiological and pathological states.
Novel transcription factors identified in human CD34 antigen (show CD34 Proteins)-positive hematopoietic stem cells.
RBaK interacts with the androgen receptor (show AR Proteins) and increases its transcriptional activity.
study found no evidence of mutations in the coding sequence and splice sites of RBaK in association with familial hyperaldosteronism type II
The role of RBaK, PMS2, and GNA12 in the inheritance of familial hyperaldosteronism type II were studied.
This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus.
RB-associated KRAB repressor
, RB-associated KRAB zinc finger protein
, zinc finger protein 769