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RGM Domain Family, Member A Proteins (RGMA)

RGMA encodes a member of the repulsive guidance molecule family. Additionally we are shipping RGMA Antibodies (44) and RGMA Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RGMA 56963 Q96B86
RGMA 244058 Q6PCX7
Rat RGMA RGMA 308739  
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Top RGMA Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,656.50
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,663.83
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$313.50
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RGMA Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

Top referenced RGMA Proteins

  1. Human RGMA Protein expressed in Human Cells - ABIN2005035 : Monnier, Sierra, Macchi, Deitinghoff, Andersen, Mann, Flad, Hornberger, Stahl, Bonhoeffer, Mueller: RGM is a repulsive guidance molecule for retinal axons. in Nature 2002 (PubMed)
    Show all 3 references for ABIN2005035

More Proteins for RGM Domain Family, Member A (RGMA) Interaction Partners

Human RGM Domain Family, Member A (RGMA) interaction partners

  1. Thus, we conclude that RGMa inhibits angiogenesis in vitro and in vivo suggesting that its manipulation would be an efficient therapeutic strategy for pro-angiogenic conditions.

  2. RGMa expression and promoter methylation status are closely related to colorectal cancer genesis and progression.

  3. identification of neogenin (show NEO1 Proteins)-binding site on the repulsive guidance molecule A

  4. The expression of RGMA, RGMB (show RGMB Proteins) and RGMC (show HFE2 Proteins) was evident in most examined prostate cancer cell lines, and also in the prostate cancer tissues

  5. Reduced expression of RGMA in breast cancer was associated with breast cancer.

  6. The full-length signal peptides of RGMa is functional and furthermore that the C-domains are sufficient and essential for ER targeting, whereas the N-domains are dispensable. Thus, the N-domains are available for additional functions.

  7. RGM-A is a unique endogenous inhibitor of leukocyte chemotaxis that limits inflammatory leukocyte traffic

  8. Following central nervous system injury, RGM, a novel, potent axonal growth inhibitor, is present in axonal growth impediments: the mature myelin, choroid plexus, and components of the developing scar.

  9. RGMa facilitates the use of ActRIIA by endogenous BMP2 and BMP4 ligands that otherwise prefer signaling via BMPRII and increased utilization of ActRIIA leads to generation of an enhanced BMP signal

  10. detected a homozygous deletion of chromosomal region 15q26.2 in the cell line HDLM2 encompasing RGMA and CHD2

Mouse (Murine) RGM Domain Family, Member A (RGMA) interaction partners

  1. RGMa is involved in Th17-cell-mediated neurodegeneration.

  2. repulsive RGMa-Neogenin (show NEO1 Proteins) interactions drive interneurons into the migratory corridor

  3. Postnatal spiral ganglion neurons retain capacity to send out processes that respond to signals for synaptogenesis, but postnatal RGMa expression appears to be detrimental to regeneration of afferent hair cell innervation and antagonizes synaptogenesis

  4. RGMa inhibits axon growth by phosphorylating CRMP-2 via both Rho-kinase and GSK-3beta signaling pathways.

  5. Strong expression of RGMa, RGMb (show RGMB Proteins) and Neogenin (show NEO1 Proteins) protein was found on several major axon tracts such as the primary olfactory projections, anterior commissure and fasciculus retroflexus.

  6. RGMa enhances CD4 (show CD4 Proteins)+ T cell activation facilitating central nervous system intervention in an animal model of multiple sclerosis presented in this review.

  7. Loss-of-function analysis in mice revealed that RGMa may play a more important role in neural tube morphogenesis.

  8. identification of neogenin (show NEO1 Proteins)-binding site on the repulsive guidance molecule A

  9. activated microglia play a major role in inhibiting axon regeneration via RGMa

  10. RGM-A is a unique endogenous inhibitor of leukocyte chemotaxis that limits inflammatory leukocyte traffic

RGMA Protein Profile

Protein Summary

This gene encodes a member of the repulsive guidance molecule family. The encoded protein is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. This protein may also function as a tumor suppressor in some cancers. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with RGMA

  • RGM domain family, member A (RGMA)
  • RGM domain family, member A (Rgma)
  • BC059072 protein
  • C230063O06 protein
  • RGM protein

Protein level used designations for RGMA

repulsive guidance molecule A

GENE ID SPECIES
56963 Homo sapiens
244058 Mus musculus
308739 Rattus norvegicus
395214 Gallus gallus
100156429 Sus scrofa
518756 Bos taurus
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