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RIOK1 includes two alternatively spliced transcript variants, which encode different isoforms. Additionally we are shipping RIO Kinase 1 Antibodies (53) and RIO Kinase 1 Proteins (8) and many more products for this protein.
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The RIO kinase fold generates a versatile ATPase enzyme, which in the case of Rio1 is activated following the Rio2 step to regulate one of the final 40S maturation events, at which time the 60S subunit is recruited for final quality control check.
These results imply that, in glioblastoma cells, constitutive Akt (show AKT1 ELISA Kits) signaling drives RIO kinase overexpression, which creates a feedforward loop that promotes and maintains oncogenic Akt (show AKT1 ELISA Kits) activity through stimulation of mTor (show FRAP1 ELISA Kits) signaling.
RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln fo (show PRMT5 ELISA Kits)r binding and modulates PRMT5 complex composit (show NCL ELISA Kits)ion and substrate specificity.
Describes a function for human RIOK1 as a component of the protein arginine methyltransferase 5 (show PRMT5 ELISA Kits) complex, conferring specificity for nucleolin (show NCL ELISA Kits) as a methylation substrate.
This gene includes two alternatively spliced transcript variants, which encode different isoforms. The function of this gene has not been determined.
serine/threonine-protein kinase RIO1