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RBMS3 encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. Additionally we are shipping RBMS3 Antibodies (24) and many more products for this protein.
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binding of Rbms3 to the 3'UTR of Ptf1a (show PTF1A Proteins) regulates the production of the Ptf1a (show PTF1A Proteins) protein
one interacting gene pair (RBMS3 versus ZNF516) which, even after Bonferroni correction for multiple testing, showed consistently significant effects on hip bone mineral density.
RBMS3 is a novel tumor suppressor gene in lung squamous cell carcinoma
RBMS3 at 3p24 inhibits nasopharyngeal carcinoma development via inhibiting cell proliferation, angiogenesis, and inducing apoptosis
genetic susceptibility plays a role in the pathophysiology of Bisphosphonate-related osteonecrosis of the jaw (BRONJ), with RBMS3 having a significant effect in the risk.
a tumor suppression function for the human RBMS3 gene in esophageal squamous cell carcinoma, acting through c-Myc (show MYC Proteins) downregulation, with genetic loss of this gene contributing to poor outcomes in disease
These results suggest that RBMS3, by binding Prx1 (show PRDX1 Proteins) mRNA in a sequence-specific manner, controls Prx1 (show PRDX1 Proteins) expression and indirectly collagen synthesis.
This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
RNA binding motif, single stranded interacting protein
, RNA binding motif, single stranded interacting protein 3
, RNA-binding motif, single-stranded-interacting protein 3
, RNA-binding protein RBMS3
, RNA-binding protein