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RNA Binding Motif Protein 38 Proteins (RBM38)

RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. Additionally we are shipping RNA Binding Motif Protein 38 Antibodies (27) and RNA Binding Motif Protein 38 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RBM38 55544 Q9H0Z9
RBM38 56190 Q62176
Rat RBM38 RBM38 366262  
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Top RNA Binding Motif Protein 38 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,530.00
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,531.83
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RBM38 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for RNA Binding Motif Protein 38 (RBM38) Interaction Partners

Xenopus laevis RNA Binding Motif Protein 38 (RBM38) interaction partners

  1. The data suggested that XSeb4R is a novel player in gene expression regulation, acting at the posttranscriptional level during ectoderm specification in Xenopus.

  2. Ablation of XSeb4R activity results in impairment of endoderm and mesoderm formation, while ectopic expression of XSeb4R in ectodermal cells induces endodermal and mesodermal gene expression.

Human RNA Binding Motif Protein 38 (RBM38) interaction partners

  1. RBM38 and DND1 (show DND1 Proteins) are repressed in primary acute myeloid leukemia (show BCL11A Proteins), neutrophil differentiation is dependent on increased expression of both proteins, and they have a role in regulating p21(CIP1 (show CDKN1A Proteins)) expression during acute promyelocytic leukemia (show PML Proteins) differentiation

  2. RNPC1 was found to be expressed in bladder, blood, brain, breast, colorectal, eye, head and neck, lung, ovarian, skin and soft tissue cancer. In 14 of the 94 tests, an association between RNPC1 gene expression and cancer prognosis was observed.

  3. our data suggest that RBM38 is a novel translational regulator of HIF1alpha (show HIF1A Proteins) under a hypoxic condition.

  4. Suggest that RNPC1 had a potential function to play a tumor-suppressor role which may be a potential marker in the therapeutic and prognostic of breast cancer.

  5. Data indicate that long non-coding RNA HOTAIR is functionally related to RNA binding motif protein 38 (RBM38).

  6. RBM38 as novel transcriptional target of E2F1 (show E2F1 Proteins) restricts E2F1 (show E2F1 Proteins)-induced proliferation. Furthermore, this negative feedback loop seems to restrict tumor aggressiveness, thereby promoting survival of patients with cancer.

  7. A role for RBM38 in regulating alternative splicing during erythroid differentiation.

  8. Data suggest that RNPC1 is a critical regulator of Mdm2 (show MDM2 Proteins).

  9. GSK3 promotes p53 (show TP53 Proteins) mRNA translation through phosphorylation of RNPC1

  10. knockdown of MIC-1 (show C18orf8 Proteins) can decrease RNPC1-induced cell growth suppression.

Mouse (Murine) RNA Binding Motif Protein 38 (RBM38) interaction partners

  1. Rbm38 deficiency markedly decreases the tumor penetrance in mice heterozygous for p53 (show TP53 Proteins) via enhanced p53 (show TP53 Proteins) expression.

  2. knockdown of MIC-1 (show GDF15 Proteins) can decrease RNPC1-induced cell growth suppression.

  3. knockdown of p73 (show ARHGAP24 Proteins) or p21, another target of RNPC1, attenuates the inhibitory effect of RNPC1 on cell proliferation and premature senescence, whereas combined knockdown of p73 (show ARHGAP24 Proteins) and p21 completely abolishes it

  4. a novel mechanism by which HuR (show ELAVL1 Proteins) is regulated by RNPC1 via mRNA stability and HuR (show ELAVL1 Proteins) is a mediator of RNPC1-induced growth suppression.

  5. loss of RNPC1 in mouse embryonic fibroblasts increased the level of p53 (show TP53 Proteins) protein, leading to enhanced premature senescence in a p53 (show TP53 Proteins)-dependent manner

RNA Binding Motif Protein 38 (RBM38) Protein Profile

Protein Summary

RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell- specific isoform of FGFR2 (By similarity). Plays a role in myogenic differentiation.

Gene names and symbols associated with RBM38

  • RNA binding motif protein 38 (rbm38)
  • RNA binding motif protein 38 (RBM38)
  • RNA binding motif protein 38 (Rbm38)
  • dJ800J21.2 protein
  • fi25e12 protein
  • HSRNASEB protein
  • MGC89204 protein
  • Rnpc1 protein
  • Seb4 protein
  • SEB4B protein
  • SEB4D protein
  • Seb4l protein
  • wu:fi25e12 protein
  • xseb4r protein
  • YF-55 protein
  • zgc:92336 protein

Protein level used designations for RBM38

RNA binding motif protein 38 , RNA-binding protein 38 , RNA-binding motif protein 38 , RNA-binding region (RNP1, RRM) containing 1 , RNA-binding region containing 1 , RNA-binding protein XSeb4R , RRM-type RNA-binding protein XSEB4R , hypothetical protein , CLL-associated antigen KW-5 , RNA-binding region-containing protein 1 , ssDNA-binding protein SEB4 , seb4 mRNA

GENE ID SPECIES
448763 Xenopus (Silurana) tropicalis
333991 Danio rerio
398603 Xenopus laevis
768866 Gallus gallus
55544 Homo sapiens
611796 Canis lupus familiaris
100125973 Sus scrofa
533516 Bos taurus
56190 Mus musculus
366262 Rattus norvegicus
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