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RBM5 is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. Additionally we are shipping RNA Binding Motif Protein 5 Proteins (5) and RNA Binding Motif Protein 5 Kits (1) and many more products for this protein.
Showing 10 out of 78 products:
Human Polyclonal RBM5 Primary Antibody for WB - ABIN658821
Sugliani, Brambilla, Clerkx, Koornneef, Soppe: The conserved splicing factor SUA controls alternative splicing of the developmental regulator ABI3 in Arabidopsis. in The Plant cell 2010
Show all 5 references for ABIN658821
Human Polyclonal RBM5 Primary Antibody for EIA, WB - ABIN954485
Rintala-Maki, Sutherland: Identification and characterisation of a novel antisense non-coding RNA from the RBM5 gene locus. in Gene 2009
Show all 4 references for ABIN954485
Chicken Polyclonal RBM5 Primary Antibody for WB - ABIN2780715
Oh, Boctor, Jimenez, Lopez, Koegel, Taschereau, Phan, Jacobsen, Slamon: Promoter methylation study of the H37/RBM5 tumor suppressor gene from the 3p21.3 human lung cancer tumor suppressor locus. in Human genetics 2008
Human Polyclonal RBM5 Primary Antibody for ICC, IF - ABIN4349633
Jackson, Du, Janesko-Feldman, Vagni, Dezfulian, Poloyac, Jackson, Clark, Kochanek: The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2015
Human Polyclonal RBM5 Primary Antibody for IHC, ELISA - ABIN1533772
Timmer, Terpstra, van den Berg, Veldhuis, Ter Elst, van der Veen, Kok, Naylor, Buys: An evolutionary rearrangement of the Xp11.3-11.23 region in 3p21.3, a region frequently deleted in a variety of cancers. in Genomics 1999
Results show that RBM5 is downregulated in smoke induced tumor; its overexpression inhibits tumor growth through cell cycle arrest and induction of apoptosis suggesting the importance of RBM5 in the pathogenesis of smoking-related cancer.
ICG-001 had no apparent effect on the RBM5 levels.
RBM5 knockdown in human neuronal cells decreases caspase activation by staurosporine.
Antagonizes the effects of RBM5, RBM6 (show RBM6 Antibodies), and RBM10 (show RBM10 Antibodies) in cell colony formation.
Loss of RBM5 expression is associated with lung adenocarcinoma.
expression of RBM5 protein was significantly decreased in cancerous prostatic tissues compared to the normal tissues
RBM5 can inhibit the growth of lung cancer cells and induce apoptosis both in vitro and in vivo.
Expression of RBM5 mRNA and protein was negatively correlated with expression of EGFR and KRAS mRNA and protein in NSCLC tissues.
RBM5 promotes exon 4 skipping of AID pre-mRNA by competing with the binding of U2AF65 (show U2AF59 Antibodies) to the polypyrimidine tract.
RBM5 may serve as a biomarker with the ability to predict a response to cisplatin
Expression of Rbm5 and Rbm10 (show RBM10 Antibodies) RNA remained constant during C2C12 myogenesis, but protein levels significantly decreased.
The RBM5/10 staining was higher 48 to 72 hours after traumatic brain injury and appeared to be increased in neuronal nuclei (show RBFOX3 Antibodies) of the hippocampus.
Our findings also suggest that the second RRM of RBM5 is pivotal for appropriate pre-mRNA splicing.
This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.
RNA binding motif protein 5
, RNA-binding motif protein 5-B
, RNA-binding protein 5-B
, RNA-binding motif protein 5
, RNA-binding protein 5
, RNA-binding protein 5-like
, RNA-binding motif protein 5-A
, RNA-binding protein 5-A
, putative tumor suppressor LUCA15
, renal carcinoma antigen NY-REN-9
, G15 protein
, tumor suppressor LUCA15