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RNA Binding Motif Protein 5 Proteins (RBM5)

RBM5 is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. Additionally we are shipping RNA Binding Motif Protein 5 Antibodies (74) and RNA Binding Motif Protein 5 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RBM5 10181 P52756
RBM5 83486 Q91YE7
Rat RBM5 RBM5 300996 B2GV05
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Top RNA Binding Motif Protein 5 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RBM5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for RNA Binding Motif Protein 5 (RBM5) Interaction Partners

Human RNA Binding Motif Protein 5 (RBM5) interaction partners

  1. ICG-001 had no apparent effect on the RBM5 levels.

  2. RBM5 knockdown in human neuronal cells decreases caspase activation by staurosporine.

  3. Antagonizes the effects of RBM5, RBM6 (show RBM6 Proteins), and RBM10 (show RBM10 Proteins) in cell colony formation.

  4. Loss of RBM5 expression is associated with lung adenocarcinoma.

  5. expression of RBM5 protein was significantly decreased in cancerous prostatic tissues compared to the normal tissues

  6. RBM5 can inhibit the growth of lung cancer cells and induce apoptosis both in vitro and in vivo.

  7. Expression of RBM5 mRNA and protein was negatively correlated with expression of EGFR and KRAS mRNA and protein in NSCLC tissues.

  8. RBM5 promotes exon 4 skipping of AID pre-mRNA by competing with the binding of U2AF65 (show U2AF59 Proteins) to the polypyrimidine tract.

  9. RBM5 may serve as a biomarker with the ability to predict a response to cisplatin

  10. The results suggest that RBM5 expression is not directly regulated by EGFR (show EGFR Proteins) in non-smoker related lung adenocarinomas.

Mouse (Murine) RNA Binding Motif Protein 5 (RBM5) interaction partners

  1. Expression of Rbm5 and Rbm10 (show RBM10 Proteins) RNA remained constant during C2C12 myogenesis, but protein levels significantly decreased.

  2. The RBM5/10 staining was higher 48 to 72 hours after traumatic brain injury and appeared to be increased in neuronal nuclei (show RBFOX3 Proteins) of the hippocampus.

  3. Our findings also suggest that the second RRM of RBM5 is pivotal for appropriate pre-mRNA splicing.

RNA Binding Motif Protein 5 (RBM5) Protein Profile

Protein Summary

This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.

Gene names and symbols associated with RBM5

  • RNA binding motif protein 5 (rbm5)
  • RNA binding motif protein 5 (rbm5-b)
  • RNA binding motif protein 5 (RBM5)
  • RNA binding motif protein 5 (rbm5-a)
  • RNA binding motif protein 5 (Rbm5)
  • D030069N10Rik protein
  • G15 protein
  • h37 protein
  • LUCA15 protein
  • RBM5 protein
  • RMB5 protein
  • wu:fc25a08 protein
  • wu:fe06f12 protein

Protein level used designations for RBM5

RNA binding motif protein 5 , RNA-binding motif protein 5-B , RNA-binding protein 5-B , RNA-binding motif protein 5 , RNA-binding protein 5 , RNA-binding protein 5-like , RNA-binding motif protein 5-A , RNA-binding protein 5-A , putative tumor suppressor LUCA15 , renal carcinoma antigen NY-REN-9 , G15 protein , tumor suppressor LUCA15

GENE ID SPECIES
324302 Danio rerio
446596 Xenopus laevis
550032 Xenopus (Silurana) tropicalis
704114 Macaca mulatta
744612 Pan troglodytes
100402537 Callithrix jacchus
100587459 Nomascus leucogenys
779346 Xenopus laevis
10181 Homo sapiens
476618 Canis lupus familiaris
534216 Bos taurus
83486 Mus musculus
300996 Rattus norvegicus
100515237 Sus scrofa
415947 Gallus gallus
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