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Possible involved in germ cell RNA processing and meiosis (By similarity). Additionally we are shipping RBM7 Antibodies (27) and many more products for this protein.
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Knock-down of rbm7, exosc8 (show EXOSC8 Proteins) and exosc3 (show EXOSC3 Proteins) in zebrafish showed a common pattern of defects in motor neurons and cerebellum. Our data indicate that impaired RNA metabolism may underlie the clinical phenotype by fine tuning gene expression which is essential for correct neuronal differentiation
RBM8 (show RBM8A Proteins) and CBP20 (show NCBP2 Proteins) RRM-domain crystal structures were used to successfully determine the RBM7 structure by molecular replacement. The structure reveals a ring-shaped pentameric assembly, which is most likely a consequence of crystal packing
Phosphorylation of RBM7 by the p38(MAPK (show MAPK14 Proteins))/MK2 (show KCNA2 Proteins) axis increases nuclear ncRNA stability by blocking their RBM7-binding and subsequent RNA exosome targeting to allow stress-dependent modulations of the noncoding transcriptome.
Possible involved in germ cell RNA processing and meiosis (By similarity).
RNA binding motif protein 7
, RNA-binding motif protein 7
, RNA-binding protein 7