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Two types of spliceosomes catalyze splicing of pre-mRNAs. Additionally we are shipping RNP Proteins (5) and many more products for this protein.
Showing 10 out of 22 products:
Cow (Bovine) Polyclonal RNP Primary Antibody for WB - ABIN2779114
Benecke, Lührmann, Will: The U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11-59K protein. in The EMBO journal 2005
Recessive lethal point mutation leads to formation of aberrant U11- and U12-containing small nuclear ribonucleoproteins that impair the efficiency of U12-type splicing.
Exome analysis of one proband revealed missense (c.1320C>A, p.P474T) and nonsense (c.1504C>T, p.R502X) mutations in the RNPC3 gene.
U11/U12-65K contribute to di-snRNP (show LSM2 Antibodies) formation and intron bridging in the minor prespliceosome
Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.
RNA-binding region (RNP1, RRM) containing 3
, RNA-binding protein 40
, RNA recognition protein
, RNA-binding motif protein 40
, RNA-binding region-containing protein 3
, U11/U12 small nuclear ribonucleoprotein 65 kDa protein
, U11/U12 snRNP 65 kDa protein
, U11/U12 snRNP 65K