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RIOK3 was identified by the similarity of its product to the Aspergillus nidulans SUDD protein, an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a restrictive temperature. Additionally we are shipping RRIO Kinase 3 Proteins (6) and RRIO Kinase 3 Kits (3) and many more products for this protein.
Showing 10 out of 49 products:
Human Monoclonal RIOK3 Primary Antibody for IP, ELISA - ABIN563783
Kimmelman, Hezel, Aguirre, Zheng, Paik, Ying, Chu, Zhang, Sahin, Yeo, Ponugoti, Nabioullin, Deroo, Yang, Wang, McGrath, Protopopova, Ivanova, Zhang, Feng, Tsao, Redston, Protopopov, Xiao, Futreal et al.: Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer. ... in Proceedings of the National Academy of Sciences of the United States of America 2008
Show all 2 Pubmed References
Cow (Bovine) Polyclonal RIOK3 Primary Antibody for WB - ABIN2775269
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007
the ectopic expression of RIOK3 or a phosphomimetic MDA5 (show IFIH1 Antibodies)-S828D mutation attenuated MDA5 (show IFIH1 Antibodies)-mediated signaling.
These findings demonstrate that RIOK3 is necessary for maintaining actin cytoskeletal organisation required for migration and invasion, biological processes that are necessary for hypoxia-driven metastasis.
Functionally, RIOK3 acts as a SUFU (show SUFUH Antibodies)-dependent positive regulator of Hedgehog (show SHH Antibodies) signaling.
Authors found that RIOK3 physically interacts with TBK1 (show TBK1 Antibodies) and IRF3 (show IRF3 Antibodies) and bridges the functions between TBK1 (show TBK1 Antibodies) and IRF3 (show IRF3 Antibodies) in the activation of type I interferon (show IFNA Antibodies) pathway.
RioK3 is a novel cytoplasmic component of pre-40S pre-ribosomal particle(s) in human cells, required for normal processing of the 21S pre-rRNA.
Like RIOK3, PAK4 (show PAK4 Antibodies) promotes pancreas ductal cell motility and invasion in pancreatic cancer
down-regulation of miR (show MLXIP Antibodies)-191 is essential for erythroid chromatin condensation and enucleation by allowing up-regulation of Riok3 and Mxi1 (show MXI1 Antibodies)
This gene was identified by the similarity of its product to the Aspergillus nidulans SUDD protein, an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a restrictive temperature. The specific function of this gene has not yet been determined.
homolog of the Aspergillus nidulans sudD gene product
, serine/threonine-protein kinase RIO3
, sudD (suppressor of bimD6, Aspergillus nidulans) homolog
, sudD homolog
, sudD suppressor of Aspergillus nidulans bimD6 homolog
, sudD suppressor of bimD6 homolog
, sudD, suppressor of bimD6 homolog
, RIO kinase 3