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RRN3 RNA Polymerase I Transcription Factor Homolog (S. Cerevisiae) Proteins (RRN3)

Required for efficient transcription initiation by RNA polymerase I. Additionally we are shipping RRN3 RNA Polymerase I Transcription Factor Homolog (S. Cerevisiae) Antibodies (49) and RRN3 RNA Polymerase I Transcription Factor Homolog (S. Cerevisiae) Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RRN3 54700 Q9NYV6
Rat RRN3 RRN3 304714  
RRN3 106298 B2RS91
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Top RRN3 RNA Polymerase I Transcription Factor Homolog (S. Cerevisiae) Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

RRN3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for RRN3 RNA Polymerase I Transcription Factor Homolog (S. Cerevisiae) (RRN3) Interaction Partners

Fruit Fly (Drosophila melanogaster) RRN3 RNA Polymerase I Transcription Factor Homolog (S. Cerevisiae) (RRN3) interaction partners

  1. muscle ribosome synthesis functions as a nutrient-dependent checkpoint for overall body growth: in nutrient rich conditions, TOR is required to maintain levels of TIF-IA and ribosome synthesis to promote high levels of systemic insulin (show INS Proteins)

Human RRN3 RNA Polymerase I Transcription Factor Homolog (S. Cerevisiae) (RRN3) interaction partners

  1. These data support a model in which activated Akt (show AKT1 Proteins) enhances rRNA synthesis both by preventing TIF-IA degradation and phosphorylating CK2alpha, which in turn phosphorylates TIF-IA.

  2. DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription

  3. reveals the molecular basis of Rrn3-regulated Pol I initiation and cell growth

  4. Data show that nutrient starvation, density arrest and protein synthesis inhibitors inactivate transcription initiation factor-IA and impair its association with RNA polymerase I (show POLR1C Proteins).

  5. ERK (show EPHB2 Proteins)-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I (show POLR1C Proteins) transcription and cell growth.

  6. Phosphorylation of S44 activates and S199 inactivates TIF-IA.

  7. The definition of the Alu element within the TIF-IA gene as an exon is restricted to certain types of cancers; the element is not exonized in normal human cells.

  8. CK2 phosphorylates the transcription initiation factor TIF-IA at serines 170 and 172 (Ser170/172), and this phosphorylation triggers the release of TIF-IA from Pol I after transcription initiation.

Mouse (Murine) RRN3 RNA Polymerase I Transcription Factor Homolog (S. Cerevisiae) (RRN3) interaction partners

  1. These data support a model in which activated Akt (show AKT1 Proteins) enhances rRNA synthesis both by preventing TIF-IA degradation and phosphorylating CK2alpha, which in turn phosphorylates TIF-IA.

  2. DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription

  3. Ablation of TIF-IA leads to impaired nucleolar activity and results in increased levels of the proapoptotic transcription factor p53 (show TP53 Proteins) in both neural progenitors and hippocampal neurons but induces rapid apoptosis only in neural progenitors.

  4. Rrn3 regulates rDNA transcription by determining the steady-state concentration of the Rrn3.RNA polymerase I (show POLR1C Proteins) complex within the nucleolus. (RRN3)

  5. ERK (show EPHB2 Proteins)-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I (show POLR1C Proteins) transcription and cell growth.

  6. Genetic inactivation of Tif1a (show TRIM24 Proteins) leads to nucleolar disruption, cell cycle arrest, and p53 (show TP53 Proteins)-mediated apoptosis.

RRN3 RNA Polymerase I Transcription Factor Homolog (S. Cerevisiae) (RRN3) Protein Profile

Protein Summary

Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction.

Gene names and symbols associated with RRN3

  • RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) (RRN3)
  • RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) (rrn3)
  • CG3278 gene product from transcript CG3278-RA (Tif-IA)
  • DyakGE12956-PA (DyakTif-IA)
  • RRN3 RNA polymerase I transcription factor homolog (rrn3)
  • RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) (Rrn3)
  • RRN3 RNA polymerase I transcription factor homolog (yeast) (Rrn3)
  • A-270G1.2 protein
  • AL023001 protein
  • CG3278 protein
  • CG5951 protein
  • CG16938 protein
  • DKFZp459B073 protein
  • Dmel\\CG3278 protein
  • dTIF-IA protein
  • DyakGE12956 protein
  • dyak_GLEANR_13182 protein
  • E130302O19Rik protein
  • GE12956 protein
  • R75565 protein
  • RGD1305001 protein
  • RRN3 protein
  • Tif-1A protein
  • Tif-IA protein
  • Tif1a protein
  • TIFIA protein

Protein level used designations for RRN3

RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) , RRN3 RNA polymerase I transcription factor homolog , RNA polymerase I-specific transcription initiation factor RRN3 , RNA polymerase I-specific transcription initiation factor RRN3-like , CG3278-PA , CG3278-PC , Tif-IA-PA , Tif-IA-PC , DyakGE12956-PA , DyakTif-IA-PA , GE12956-PA , Tif-IA , TIF-IA , transcription initiation factor IA , transcription initiation factor TIF-IA

GENE ID SPECIES
713500 Macaca mulatta
741314 Pan troglodytes
100023594 Monodelphis domestica
100054032 Equus caballus
100089040 Ornithorhynchus anatinus
100173945 Pongo abelii
100346876 Oryctolagus cuniculus
100391144 Callithrix jacchus
100469324 Ailuropoda melanoleuca
100497648 Xenopus (Silurana) tropicalis
100541012 Meleagris gallopavo
100600176 Nomascus leucogenys
100624003 Sus scrofa
35454 Drosophila melanogaster
6532176 Drosophila yakuba
443681 Xenopus laevis
416414 Gallus gallus
54700 Homo sapiens
479838 Canis lupus familiaris
515964 Bos taurus
304714 Rattus norvegicus
106298 Mus musculus
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