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anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) Antibodies

RASSF1 encodes a protein similar to the RAS effector proteins. Additionally we are shipping Ras Association (RalGDS/AF-6) Domain Family Member 1 Proteins (6) and Ras Association (RalGDS/AF-6) Domain Family Member 1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RASSF1 11186 Q9NS23
RASSF1 56289 Q99MK9
RASSF1 363140  
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Top anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 Antibodies at antibodies-online.com

Showing 10 out of 138 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-RASSF1A Polyclonal Antibody, Unconjugated (ABIN673764) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin-embedded human oral squamous cell labeled with Anti-RASSF1A Polyclonal Antibody, Unconjugated (ABIN673764) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, PE conjugated used at 1:200 dilution for 40 minutes at 37°C. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated EIA, IF, WB Western blot analysis The extracts of HeLa (H) cells , mouse brain (MB), mouse liver (ML) and mouse kidney (MK) tissues (each 20 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human RASSF1A (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a ECL detection system. Arrows indicate RASSF1A protein (about 40kDain HeLa cells, and 43kDa in other tissues). Agathanggelou A. et al 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-RASSF1 AntibodyTitration: 1.0 µg/mL  Positive Control: Fetal Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC213525 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-RASSF1 antibody (ABIN2454291), and then analyzed by flow cytometry. Anti-RASSF1 mouse monoclonal antibody (ABIN2454291) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RASSF1 (RC213525). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-RASSF1 mouse monoclonal antibody (ABIN2454275) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RASSF1 (RC213525). Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-RASSF1 mouse monoclonal antibody. (ABIN2454275) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Mouse Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Mouse Un-conjugated ICC, ELISA, WB 100 μL Log in to see 7 to 8 Days
$374.00
Details
Human Mouse Un-conjugated IF, WB Anti-RASSF1 mouse monoclonal antibody (ABIN2454271) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RASSF1 (RC213525). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RASSF1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-RASSF1. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC213525 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-RASSF1 antibody (ABIN2454272), and then analyzed by flow cytometry. Anti-RASSF1 mouse monoclonal antibody (ABIN2454272) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RASSF1 (RC213525). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-RASSF1 mouse monoclonal antibody (ABIN2454254) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RASSF1 (RC213525). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RASSF1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-RASSF1. 100 μL Log in to see 2 to 3 Days
$482.90
Details

RASSF1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 Antibodies

  1. Human Monoclonal RASSF1 Primary Antibody for ICC, ELISA - ABIN165456 : Agathanggelou, Cooper, Latif: Role of the Ras-association domain family 1 tumor suppressor gene in human cancers. in Cancer research 2005 (PubMed)
    Show all 4 references for ABIN165456

  2. Human Monoclonal RASSF1 Primary Antibody for EIA, IF - ABIN121164 : Dammann, Schagdarsurengin, Seidel, Strunnikova, Rastetter, Baier, Pfeifer: The tumor suppressor RASSF1A in human carcinogenesis: an update. in Histology and histopathology 2005 (PubMed)
    Show all 4 references for ABIN121164

  3. Mouse (Murine) Polyclonal RASSF1 Primary Antibody for ELISA, WB - ABIN190784 : Yan, Venkataramu, Ibrahim, Liu, Shen, Diaz, Centeno, Weber, Leu, Shapiro, Eng, Yeatman, Huang: Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue. in Clinical cancer research : an official journal of the American Association for Cancer Research 2006 (PubMed)

  4. Human Polyclonal RASSF1 Primary Antibody for IF (p), IHC (p) - ABIN673764 : Liu, Ao, Zhou, Cui, Zhou, Yuan, Xiang, Cao, Liu: CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine. in Biochemical and biophysical research communications 2010 (PubMed)

More Antibodies against Ras Association (RalGDS/AF-6) Domain Family Member 1 Interaction Partners

Human Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) interaction partners

  1. Different genetic mechanisms seem to contribute to RASSF1 deregulation in this setting, but RASSF1 methylation does not seem to substantially affect RASSF1 isoforms expression.

  2. RASSF1C gene is not involved in Clear-cell renal cell carcinoma (show MOK Antibodies) (ccRCC)progression and we propose that the measurements of RASSF1A mRNA levels in paired tumor-normal kidney tissue could serve as a new prognostic factor in ccRCC

  3. Distinct RASSF1 isoforms have opposing functions, which provide a biomarker for YAP1 (show YAP1 Antibodies) activation and explain correlations of RASSF1 methylation with advanced invasive disease in humans.

  4. Results indicate that hypermethylation of tumor suppressor protein (show TP53 Antibodies) RASSF1A and docking protein 1 (DOK1 (show DOK1 Antibodies)) contributes to hepatocarcinogenesis and is associated to clinicopathological characteristics.

  5. RASSF1 acts to restrict EMT (show ITK Antibodies) and invasion by indirectly controlling YAP (show YAP1 Antibodies) nuclear shuttling.

  6. Data indicate tumor suppressors TP73 (show TP73 Antibodies), RASSF1A, MLH1 (show MLH1 Antibodies) and BRCA1 as possible biomarkers to distinguish Pleomorphic invasive lobular cancer (pleomorphic ILC (show CCL27 Antibodies)} from classic ILC (show CCL27 Antibodies) and infiltrative ductal cancer (IDC (show LMNA Antibodies)).

  7. Interaction between HPV infection and RASSF1A promoter methylation is associated with the development of cervical cancers.

  8. Hypermethylation of RASSF1A gene promoter is associated with esophageal squamous cell carcinoma.

  9. RASSF1A promotes the translocation of cytosolic PRMT5 (show PRMT5 Antibodies) to microtubules.PRMT5 co-localizes with RASSF1A on stabilized microtubules.

  10. Tumor-adjacent tissues showed higher methylation status of RASSF1A, HIN-1 (show OTUD4 Antibodies) and MGMT (show MGMT Antibodies) promoters.

Mouse (Murine) Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) interaction partners

  1. essential role of RASSF1A in regulating TNF-alpha (show TNF Antibodies) signalling in cardiomyocytes, with RASSF1A being key in the formation of the TNFR (show TNFRSF1A Antibodies) complex and in signal transmission to the downstream targets

  2. RASSF1A may function to interfere and restrict TLR-driven activation of NF-kappaB (show NFKB1 Antibodies) and is essential for protection against inflammation-induced injury.

  3. nickel-smelting fumes upregulated the expression of RASSF1A. This suggest that nickel-smelting fumes could be toxic to cells, inducing cell apoptosis and necrosis.

  4. Loss of RASSF1A synergizes with deregulated RUNX2 (show RUNX2 Antibodies) signaling in tumorigenesis.

  5. Concomitant with the loss of Rassf1a, the loss of p53 (show TP53 Antibodies) (which causes unrestrained propagation of tetraploids into aneuploid cells) further undermines genomic stability and accelerates tumorigenesis.

  6. Data show that methylation of CCND-2 (show CCND2 Antibodies), p16 (show CDKN2A Antibodies), RAR-beta (show RARB Antibodies) and RASSF-1a was significantly more prevalent in tumor than in normal tissue specimens.

  7. Rassf1A acts as a tumor suppressor gene.

  8. cooperation between inactivation of Rassf1a and Apc (show APC Antibodies) resulting in accelerated intestinal tumourigenesis.

  9. RASSF1A mediates p21Cip1/Waf1 (show CDKN1A Antibodies)-dependent cell cycle arrest and senescence through modulation of the Raf (show RAF1 Antibodies)-MEK (show MDK Antibodies)-ERK (show EPHB2 Antibodies) pathway and inhibition of Akt (show AKT1 Antibodies).

  10. data establish RASSF1A as a novel inhibitor of cardiac hypertrophy by modulating the extracellular regulated kinase 1/2 pathway.

Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) Antigen Profile

Protein Summary

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene names and symbols associated with RASSF1

  • nitrogen permease regulator-like 2 (S. cerevisiae) (NPRL2) antibody
  • Ras association (RalGDS/AF-6) domain family 1 (rassf1) antibody
  • Ras association (RalGDS/AF-6) domain family member 1 (RASSF1) antibody
  • rassf1 (Smp_157340) antibody
  • Ras association (RalGDS/AF-6) domain family member 1 (rassf1) antibody
  • Ras association (RalGDS/AF-6) domain family member 1 (Rassf1) antibody
  • 123F2 antibody
  • AA536941 antibody
  • AU044980 antibody
  • NORE2A antibody
  • RASSF1 antibody
  • Rassf1A antibody
  • Rassf1B antibody
  • Rassf1C antibody
  • RDA32 antibody
  • REH3P21 antibody
  • wu:fc17f02 antibody
  • zgc:92505 antibody
  • zgc:112224 antibody

Protein level used designations for RASSF1

Ras association (RalGDS/AF-6) domain family 1 , Ras association (RalGDS/AF-6) domain family member 1 , ras association domain-containing protein 1 , Ras association domain family 1 , rassf1 , WUGSC:H_LUCA12.5 , cardiac-specific ras association domain family 1 protein , pancreas-specific ras association domain family 1 protein , tumor suppressor protein RDA32 , 123F protein , RASSF1A tumor suppressor , protein 123F2

GENE ID SPECIES
425132 Gallus gallus
447811 Danio rerio
702385 Macaca mulatta
744944 Pan troglodytes
8344706 Schistosoma mansoni
100036863 Xenopus laevis
100302080 Ovis aries
11186 Homo sapiens
56289 Mus musculus
363140 Rattus norvegicus
607929 Canis lupus familiaris
510276 Bos taurus
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