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Ras Association (RalGDS/AF-6) Domain Family Member 5 Proteins (RASSF5)

RASSF5 is a member of the Ras association domain family. Additionally we are shipping RASSF5 Antibodies (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RASSF5 83593 Q8WWW0
RASSF5 54354 Q5EBH1
RASSF5 54355 O35141
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Top RASSF5 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,147.83
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RASSF5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5) Interaction Partners

Human Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5) interaction partners

  1. Ras induces the formation of a complex between NORE1A and the phosphatase PP1A (show PPP1CA Proteins), promoting the activation of the Rb tumor suppressor by dephosphorylation

  2. RASSF5 expression is negatively correlated with distant metastasis of osteosarcoma, and RASSF5 may function as a tumor suppressor in OS cells through activation of the MST1/LATS1 pathway.

  3. NORE1A allows Ras to qualitatively modify p53 (show TP53 Proteins) function to promote senescence.

  4. NORE1A has a role in Ras regulation of SCF (show KITLG Proteins)(beta-TrCP (show BTRC Proteins)) protein activity and specificity

  5. RASSF5 can act as an inhibitor or a potential positive regulator of Mst2 (show STK3 Proteins), depending on whether it binds to Mst2 (show STK3 Proteins) before or after activation-loop phosphorylation.

  6. Ubiquitin ligase Itch is a unique negative regulator of RASSF5.

  7. The RASSF gene family members RASSF5, RASSF6 (show RASSF6 Proteins) and RASSF7 show frequent DNA methylation (show HELLS Proteins) in neuroblastoma (show ARHGEF16 Proteins).

  8. crystal of NORE1 diffracted to 2.7 A resolution and belonged to space group P6(1)22, with unit-cell parameters a = b = 73.041, c = 66.092 A, alpha = beta = 90, gamma = 120 degrees

  9. These findings indicate that the control of HIPK1 (show HIPK1 Proteins) stability by Mdm2 (show MDM2 Proteins)-NORE1 has a major effect on cell behaviour, and epigenetic inactivation of NORE1 enables adenocarcinoma formation in vivo through HIPK1 (show HIPK1 Proteins) stabilization.

  10. N-terminal myr-tagged SKAP1 (show SKAP1 Proteins) for membrane binding facilitated constitutive RapL membrane and Rap1 (show RABGEF1 Proteins) binding and effectively substituted for PI3K (show PIK3CA Proteins) and TCR ligation in the activation of LFA-1 (show ITGAL Proteins) in T cells.

Mouse (Murine) Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5) interaction partners

  1. Rassf5 and Ndr1 (show STK38 Proteins) or Ndr2 (show STK38L Proteins) kinases regulate neuronal polarity through Par3 (show F2RL2 Proteins) phosphorylation.

  2. These findings indicate that the control of HIPK1 (show HIPK1 Proteins) stability by Mdm2 (show MDM2 Proteins)-NORE1 has a major effect on cell behaviour, and epigenetic inactivation of NORE1 enables adenocarcinoma formation in vivo through HIPK1 (show HIPK1 Proteins) stabilization.

  3. a direct role for RASSF5 in death receptor ligand-mediated apoptosis and provide further evidence for RASSF5 as a tumor suppressor.

  4. a novel regulatory network composed of the tumor suppressor NORE1A, the mitotic kinase Aurora A, the small GTPase Ras, and the microtubule cytoskeleton.

  5. findings define a T cell receptor "inside-out" pathway via N-SKAP1 (show SKAP1 Proteins)-C-RapL that regulates T cell adhesion, motility, and arrest times with dendritic cells in lymph nodes.

  6. findings reveal the several critical steps of Rap1 (show TERF2IP Proteins), which are RAPL-dependent and -independent, in lymphocyte trafficking

  7. mapping to chromosome 1 and sequence variation of the murine Ras effector gene Nore1

  8. Nore1 is a member of a family of Ras effector/tumor suppressors that includes RASSF1 (show RASSF1 Proteins)

  9. RAPL is a crucial immune cell trafficking regulator essential for immunosurveillance.

  10. RAPL and Mst1 localized to vesicular compartments and dynamically translocated with LFA-1 to the leading edge upon Rap1 activation.

RASSF5 Protein Profile

Protein Summary

This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RASSF5

  • Ras association (RalGDS/AF-6) domain family member 5 (RASSF5)
  • Ras association (RalGDS/AF-6) domain family member 5 (Rassf5)
  • 1300019G20Rik protein
  • AU042887 protein
  • Maxp1 protein
  • Nore1 protein
  • Nore1A protein
  • Nore1B protein
  • Rapl protein
  • RASSF3 protein

Protein level used designations for RASSF5

Rap1-binding protein , Ras association (RalGDS/AF-6) domain family 5 , Ras effector-like protein , new ras effector 1 , novel Ras effector 1 , ras association domain-containing protein 5 , regulator for cell adhesion and polarization enriched in lymphoid tissue , tumor suppressor RASSF3 , novel ras effector 1 , regulator for cell adhesion and polarization enriched in lymphoid tissues , protein interacting with guanine nucleotide exchange factor

GENE ID SPECIES
83593 Homo sapiens
54354 Mus musculus
54355 Rattus norvegicus
607454 Canis lupus familiaris
539767 Bos taurus
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